1998-09--2003-07 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
1994-09--1998-07 Bachelor: Nankai University
Achievement: Published over 60 papers in international academic journals
2012-08~Present - Chinese Academy of Sciences, Center for Excellence in Molecular Cell Science - Researcher, Research Group Leader, Doctoral Supervisor
2009-08~2012-08 - Harvard T.H. Chan School of Public Health - Yerby Fellow
2007-03~2009-07 - Harvard T.H. Chan School of Public Health - Research Assistant
2003-09~2007-02 - The Scripps Research Institute - Postdoctoral Researcher
National Distinguished Young Scientist Fund (2017): National Level
National High-Level Talent Program (Youth) (2013): National Level
National Excellent Young Scientist Fund (2013): National Level
Yerby Fellow, Harvard T.H. Chan School of Public Health (2009): Special
Julia Rowe Award, Leukemia & Lymphoma Society (2007): Special
Career Development Fellowship, Leukemia & Lymphoma Society (2006): Special
Di'ao Scholarship, Shanghai Institute of Biochemistry and Cell Biology (2002): Institute Level
Di'ao Scholarship, Shanghai Institute of Biochemistry and Cell Biology (2001): Institute Level
Research
Stem Cells and Bone Biology
TET enzymes regulate skeletal development through increasing chromatin accessibility of RUNX2 target genes, Wang L, You X, Ruan D, Shao R, Dai H, Shen W, Xu G, Liu W, Zou W, 2022
Discovery and application of postnatal nucleus pulposus progenitors essential for intervertebral disc homeostasis and degeneration, Gao B, Jiang B, Xing W, Xie Z, Luo Z, Zou W, 2022
The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPARγ signaling, Suo J, Zou S, Wang J, Han Y, Zhang L, Lv C, Jiang B, Ren Q, Chen L, Yang L, Ji P, Zheng X, Hu P, Zou W, 2022
Mechanical regulation of bone remodeling, Wang L, You X, Zhang L, Zhang C, Zou W, 2022
H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair, Shao R, Zhang Z, Xu Z, Ouyang H, Wang L, Ouyang H, Greenblatt M, Chen X, Zou W, 2021
Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification, Feng H, Xing W, Han W, Sun J, Kong M, Gao B, Yang Y, Yin Z, Chen X, Zhao Y, Bi Q, Zou W, 2020
Histone demethylase LSD1 is critical for endochondral ossification during bone fracture healing, Sun J, Feng H, Xing W, Han Y, Suo J, Yallowitz A, Qian N, Shi Y, Greenblatt M, Zou W, 2020
VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited RUNX2 transcription, Suo J, Feng X, Li J, Wang J, Wang Z, Zhang L, Zou W, 2020
Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk, Wang L, You X, Lotinun S, Zhang L, Wu N, Zou W, 2020
Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation, Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, Dai Q, Yang Y, Han A, Wei Z, Bi Q, Ji H, Kang T, Zou W, 2019
Targeted genetic screening in mice through haploid embryonic stem cells identifies critical genes in bone development, Bai M, Han Y, Wu Yu, Liao J, Li L, Wang L, Li Q, Xing W, Chen L, Zou W, Li J, 2019
H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells, Wang L, Niu N, Li L, Shao R, Ouyang H, Zou W, 2018
Paracrine and endocrine actions of bone-the functions of secretory proteins from osteoblasts, osteocytes, and osteoclasts, Han Y, You X, Xing W, Zhang Z, Zou W, 2018
Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts, Sun J, Ermann J, Niu N, Yan G, Yang Y, Shi Y, Zou W, 2018
mTOR/Raptor signaling is critical for skeletogenesis in mice through the regulation of Runx2 expression, Dai Q, Xu Z, Ma X, Niu N, Zhou S, Xie F, Jiang L, Wang J, Zou W, 2017
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts, Xu Z, Greenblatt M, Yan G, Feng H, Sun J, Lotinun S, Brady N, Baron R, Glimcher L, Zou W, 2017
Cdh1 regulates Craniofacial Development via APC-dependent Activation of Goosecoid, Shao R, Liu J, Yan G, Zhang J, Han Y, Guo J, Xu Z, Yuan Z, Liu J, Malumbres M, Wan L, Wei W, Zou W, 2016
Mediator MED23 cooperates with RUNX2 to drive osteoblast differentiation and bone development, Liu Z, Yao X, Yan G, Xu Y, Yan J, Zou W, Wang G, 2016
The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2, Zou W, Greenblatt M, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi S, Baron R, Glimcher L, Jones D, 2013
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through monoubiquitination of Goosecoid, Zou W, Chen X, Shim J, Huang Z, Brady N, Hu D, Drapp R, Sigrist K, Glimcher L, Jones D, 2011
MLK3 regulates bone development downstream of the Faciogenital Dysplasia protein FGD1, Zou W, Greenblatt M, Shim J, Kant S, Zhai B, Brady B, Hu D, Gygi S, Davis R, Jones D, Glimcher L, 2011
Cdh1 Regulates Osteoblast functions through an APC/C-independent modulation of Smurf1, Wan L, Zou W, Gao D, Inuzuka H, Drapp R, Shaik S, Eguren M, Hu D, Malumbres M, Glimcher L, Wei W, 2011