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Xi Zhi Guo
Life Science
Shanghai Jiao Tong University
Shanghai
Language: English, Chinese
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Osteoblasts Osteoclasts Bone Remodeling Osteoporosis Arthritis Pathology Drug Targets Senescence Senolytics Foxp1 Gene Aging Diseases Cellular Basis Therapeutic Strategies Gene Regulation Aging Regulation Obesity Type 2 Diabetes Human Genome Lifestyle Changes Regulatory Effects
Areas of Focus
  • Bone development and metabolism
  • Aging regulation of mesenchymal stem cells
  • Fat metabolism and diabetes
Academic Background & Achievements
  • Bachelor: Wuhan University
  • PhD: Shanghai Institute of Plant Physiology and Ecology, Chinese Academy of Sciences
  • Postdoctoral Researcher: NIH Human Genome Research Institute, USA
Publications
  • Foxp2 regulates anatomical features that may be relevant for vocal behavior and bipedal locomotion, Xi Zhi Guo
  • Foxp1 controls cell fate commitment and senescence of mesenchymal stem cells during skeletal aging, Xi Zhi Guo
  • Bone marrow fibrosis with fibrocytic and immunoregulatory responses induced by β-catenin activation in osteoprogenitors, Xi Zhi Guo
  • Ablation of Wntless in endosteal niches impairs lymphopoiesis rather than HSC maintenance, Xi Zhi Guo
  • Foxp1/2/4 regulate endochondral ossification as a suppresser complex, Xi Zhi Guo
  • Ectodermal Wnt signaling regulates abdominal myogenesis during ventral body wall development, Xi Zhi Guo
  • Osteoblastic Wnts differentially regulate bone remodeling and the maintenance of bone marrow mesenchymal stem cells, Xi Zhi Guo
  • Wnts-mediated reciprocal regulation between cartilage and bone development during endochondral ossification, Xi Zhi Guo
  • Ndrg2 regulates vertebral specification in differentiating somites, Xi Zhi Guo
  • Wls-mediated Wnts differentially regulate distal limb patterning and tissue morphogenesis, Xi Zhi Guo
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