Professor | Songdong Meng | Asia Growth Partners

Name	Songdong Meng
Contact Information	mengsd@im.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Songdong Meng

Contact Information

mengsd@im.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	Graduate - Chinese Academy of Sciences, Shenyang Institute of Applied Ecology PhD 2002-2007 - UT Southwestern Medical Center at Dallas, USA

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

Graduate - Chinese Academy of Sciences, Shenyang Institute of Applied Ecology
PhD
2002-2007 - UT Southwestern Medical Center at Dallas, USA

Areas of Focus	Hepatitis B Virus Immunity Tumor Immunity Vaccines and Immunopreparations
Publications	Role of innate immunity in SARS-CoV-2 infection, Zihao Wang, Fang Cheng, Yuxiu Xu, Xin Li, Songdong Meng, 2023 GPC3 and PEG10 peptides associated with placental gp96 elicit specific T cell immunity against hepatocellular carcinoma, Songdong Meng, 2023 Cellular gp96 upregulates AFP expression by blockade of NR5A2 SUMOylation and ubiquitination in HCC, Songdong Meng, 2023 A Landscape Study on COVID-19 Immunity at the Single-Cell Level, Wei, Rongguo, Qin, Zheng, Huang, Qi, Liu, Lulu, Cheng, Fang, Meng, Songdong, Wang, Lin, 2022 PEG修饰有效提高热休克蛋白gp96抑制性多肽抗乳腺癌的功能, 刘璐璐, 高建伟, 李长菲, 武岳, 孟颂东, 2022 Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway, Xie, Xialin, Hu, Liuyi, Liu, Lulu, Wang, Jiuru, Liu, Yongai, Ma, Li, Sun, Guangying, Li, Changfei, Aisa, Haji Akber, Meng, Songdong, 2022 miR-146a Maintains Immune Tolerance of Kupffer Cells and Facilitates Hepatitis B Virus Persistence in Mice, Liu, Yongai, Qin, Lijuan, Wang, Jiuru, Xie, Xialin, Zhang, Yu, Li, Changfei, Guan, Zeliang, Qian, Liyuan, Chen, Lizhao, Hu, Jun, Meng, Songdong, 2022 Quantitative determination of the electron beam radiation dose for SARS-CoV-2 inactivation to decontaminate frozen food packaging, 孟颂东, 2022 Plasma gp96 is a Novel Predictive Biomarker for Severe COVID-19, Wei, Rongguo, Zhou, Biyan, Li, Shaohua, Zhong, Debin, Li, Boan, Qin, Jianqiu, Zhao, Liping, Qin, Lixian, Hu, Jun, Wang, Jiuru, Yang, Shixiong, Zhao, Jingming, Meng, Songdong, 2021 热休克蛋白gp96在恶性肿瘤中的研究进展, 钱丽媛, 李长菲, 罗云敬, 孟颂东, 2021 Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases, Xu, Yuxiu, Liu, Erlong, Xie, Xialin, Wang, Jiuru, Zheng, Huaguo, Ju, Ying, Chen, Lizhao, Li, Changfei, Zhou, Xuyu, Li, Zihai, Li, Xin, Meng, Songdong, 2021 甲胎蛋白在肝癌的诊断和治疗中研究进展, 钱丽媛, 李长菲, 罗云敬, 孟颂东, 2021 Correction for Zhang et al., 'Broadly Protective CD8 + T Cell Immunity to Highly Conserved Epitopes Elicited by Heat Shock Protein gp96-Adjuvanted Influenza Monovalent Split Vaccine', Han Zhang, Huaguo Zheng, Peng Guo, Liuyi Hu, Zihao Wang, Jiuru Wang, Ying Ju, Songdong Meng, 2021 N-糖基化修饰对热休克蛋白gp96免疫学功能的影响, 郭鹏, 李长菲, 鞠莹, 刘二龙, 张含, 胡俊, 孟颂东, 2021 Toll样受体通路调节Tregs功能的研究进展, 郭鹏, 张含, 李长菲, 孟颂东, 2020 双特异抗体的研究进展, 叶金统, 孟颂东, 朱晓东, 2020 Extracellular gp96 is a crucial mediator for driving immune hyperactivation and liver damage, Guan, Zeliang, Ding, Yun, Liu, Yongai, Zhang, Yu, Zhao, Jingmin, Li, Changfei, Li, Zihai, Meng, Songdong, 2020 海纳百川，励志前行-纪念田波院士, 孟颂东, 2020 PD-L1 upregulation by IFN-alpha/gamma-mediated Stat1 suppresses anti-HBV T cell response, Liu, LanLan, Hou, Junwei, Xu, Yuxiu, Qin, Lijuan, Liu, Weiwei, Zhang, Han, Li, Yang, Chen, Mi, Deng, Mengmeng, Zhao, Bao, Hu, Jun, Zheng, Huaguo, Li, Changfei, Meng, Songdong, 2020 PD-L1upregulation by IFN-a/r-mediated stat1 suppresses anti-HBV T cell response, Songdong Meng, 2020 A peptide-based inhibitor of gp96 suppresses HBsAg expression and HBV replication by upregulation of p53, Qian, Liyuan, Fan, Hongxia, Ju, Ying, Chen, Lizhao, Li, Xin, Ye, Xin, Luo, Yunjing, Li, Changfei, Meng, Songdong, 2019 Dendritic cells pulsed with placental gp96 promote tumor-reactive immune responses, Zheng, Huaguo, Liu, Lanlan, Zhang, Han, Kan, Fangming, Wang, Shuo, Li, Yang, Tian, Huaqin, Meng, Songdong, 2019 Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer, Li, Xin, Xu, Yuxiu, Ding, Yun, Li, Changfei, Zhao, Hong, Wang, Jiandong, Meng, Songdong, 2018 CD8(+) T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress, Zhang, Yu, Wu, Yan, Deng, Mengmeng, Xu, Dongping, Li, Xiaodong, Xu, Zhihui, Hu, Jun, Zhang, Han, Liu, Kefang, Zhao, Yingze, Gao, Feng, Bi, Shengli, Gao, George F, Zhao, Jingmin, Liu, William J, Meng, Songdong, 2018 Disease Progress-Associated Evolution of Hepatitis B Virus Core Protein Driven By CD8(+) T-Cell Responses, Zhao, Jingmin, Zhang, Yu, Meng, Songdong, 2018 CD8+ T-Cell Responses-Associated Evolution of Hepatitis B Virus Core Protein in Disease Progress, Songdong Meng, 2018 Endogenous Cellular MicroRNAs Mediate Antiviral Defense against Influenza A Virus, Peng, Shanxin, Wang, Jing, Wei, Songtao, Li, Changfei, Zhou, Kai, Hu, Jun, Ye, Xin, Yan, Jinghua, Liu, Wenjun, Gao, George F, Fang, Min, Meng, Songdong, 2018 Hepatitis B core-related antigen (HBcrAg) correlated with HBV serum viral markers and intrahepatic indicators in treatment-naive patients with acute and chronic HBV, Zhang, Yu, Xu, Dongping, Meng, Songdong, Lu, Fengmin, Zhao, JingMin, 2017 Urokinase-type plasminogen activator receptor inhibits apoptosis in triple-negative breast cancer through miR-17/20a suppression of death receptors 4 and 5, Li, Xin, Wu, Bo, Chen, Lizhao, Ju, Ying, Li, Changfei, Meng, Songdong, 2017 Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8(+) T Cell Epitopes and Host MHC, Liu, William J, Lan, Jiaming, Liu, Kefang, Deng, Yao, Yao, Yanfeng, Wu, Shaolian, Chen, Hong, Bao, Lingling, Zhang, Haifeng, Zhao, Min, Wang, Qihui, Han, Lingxia, Chai, Yan, Qi, Jianxun, Zhao, Jincun, Meng, Songdong, Qin, Chuan, Gao, George F, Tan, Wenjie, 2017 Mapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90, Hong, Feng, Rachidi, Saleh Mohammad, Lundgren, Debbie, Han, David, Huang, Xiu, Zhao, Hongyu, Kimura, Yayoi, Hirano, Hisashi, Ohara, Osamu, Udono, Heichiiro, Meng, Songdong, Liu, Bei, Li, Zihai, 2017 CD133表位联合热休克蛋白佐剂疫苗引发抗白血病的免疫应答, 王硕, 范红霞, 李杨, 郑华国, 李鑫, 李长菲, 陈立钊, 鞠莹, 孟颂东, 2017 PTD-fused p53 as a potential antiviral agent directly suppresses HBV transcription and expression, Chu, Xiaoyu, Wu, Bo, Fan, Hongxia, Hou, Junwei, Hao, Junli, Hu, Jun, Wang, Baozhong, Liu, Guangze, Li, Changfei, Meng, Songdong, 2016 Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels, Li, Changfei, Deng, Mengmeng, Hu, Jun, Li, Xin, Chen, Lizhao, Ju, Ying, Hao, Junli, Meng, Songdong, 2016 Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response, Liu, Weiwei, Chen, Mi, Li, Xinghui, Zhao, Bao, Hou, Junwei, Zheng, Huaguo, Qiu, Lipeng, Li, Zihai, Meng, Songdong, 2016 Heat shock protein gp96 enhances T cell responses and protective potential to Bacillus Calmette-Guérin vaccine, Songdong Meng, 2016 热休克蛋白gp96 3′UTR作为ceRNA通过miR-642a调控DOHH的表达*, 盛春海, 孙璐, 初骁宇, 李长菲, 孟颂东, 2016 Hepatitis B virus mRNAs functionally sequester let-7a and enhance hepatocellular carcinoma, Deng, Mengmeng, Hou, Junwei, Hu, Jun, Wang, Shuo, Chen, Mi, Chen, Lizhao, Ju, Ying, Li, Changfei, Meng, Songdong

Areas of Focus

Hepatitis B Virus Immunity
Tumor Immunity
Vaccines and Immunopreparations

Publications

Role of innate immunity in SARS-CoV-2 infection, Zihao Wang, Fang Cheng, Yuxiu Xu, Xin Li, Songdong Meng, 2023
GPC3 and PEG10 peptides associated with placental gp96 elicit specific T cell immunity against hepatocellular carcinoma, Songdong Meng, 2023
Cellular gp96 upregulates AFP expression by blockade of NR5A2 SUMOylation and ubiquitination in HCC, Songdong Meng, 2023
A Landscape Study on COVID-19 Immunity at the Single-Cell Level, Wei, Rongguo, Qin, Zheng, Huang, Qi, Liu, Lulu, Cheng, Fang, Meng, Songdong, Wang, Lin, 2022
PEG修饰有效提高热休克蛋白gp96抑制性多肽抗乳腺癌的功能, 刘璐璐, 高建伟, 李长菲, 武岳, 孟颂东, 2022
Punicalagin promotes autophagic degradation of human papillomavirus E6 and E7 proteins in cervical cancer through the ROS-JNK-BCL2 pathway, Xie, Xialin, Hu, Liuyi, Liu, Lulu, Wang, Jiuru, Liu, Yongai, Ma, Li, Sun, Guangying, Li, Changfei, Aisa, Haji Akber, Meng, Songdong, 2022
miR-146a Maintains Immune Tolerance of Kupffer Cells and Facilitates Hepatitis B Virus Persistence in Mice, Liu, Yongai, Qin, Lijuan, Wang, Jiuru, Xie, Xialin, Zhang, Yu, Li, Changfei, Guan, Zeliang, Qian, Liyuan, Chen, Lizhao, Hu, Jun, Meng, Songdong, 2022
Quantitative determination of the electron beam radiation dose for SARS-CoV-2 inactivation to decontaminate frozen food packaging, 孟颂东, 2022
Plasma gp96 is a Novel Predictive Biomarker for Severe COVID-19, Wei, Rongguo, Zhou, Biyan, Li, Shaohua, Zhong, Debin, Li, Boan, Qin, Jianqiu, Zhao, Liping, Qin, Lixian, Hu, Jun, Wang, Jiuru, Yang, Shixiong, Zhao, Jingming, Meng, Songdong, 2021
热休克蛋白gp96在恶性肿瘤中的研究进展, 钱丽媛, 李长菲, 罗云敬, 孟颂东, 2021
Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases, Xu, Yuxiu, Liu, Erlong, Xie, Xialin, Wang, Jiuru, Zheng, Huaguo, Ju, Ying, Chen, Lizhao, Li, Changfei, Zhou, Xuyu, Li, Zihai, Li, Xin, Meng, Songdong, 2021
甲胎蛋白在肝癌的诊断和治疗中研究进展, 钱丽媛, 李长菲, 罗云敬, 孟颂东, 2021
Correction for Zhang et al., 'Broadly Protective CD8 + T Cell Immunity to Highly Conserved Epitopes Elicited by Heat Shock Protein gp96-Adjuvanted Influenza Monovalent Split Vaccine', Han Zhang, Huaguo Zheng, Peng Guo, Liuyi Hu, Zihao Wang, Jiuru Wang, Ying Ju, Songdong Meng, 2021
N-糖基化修饰对热休克蛋白gp96免疫学功能的影响, 郭鹏, 李长菲, 鞠莹, 刘二龙, 张含, 胡俊, 孟颂东, 2021
Toll样受体通路调节Tregs功能的研究进展, 郭鹏, 张含, 李长菲, 孟颂东, 2020
双特异抗体的研究进展, 叶金统, 孟颂东, 朱晓东, 2020
Extracellular gp96 is a crucial mediator for driving immune hyperactivation and liver damage, Guan, Zeliang, Ding, Yun, Liu, Yongai, Zhang, Yu, Zhao, Jingmin, Li, Changfei, Li, Zihai, Meng, Songdong, 2020
海纳百川，励志前行-纪念田波院士, 孟颂东, 2020
PD-L1 upregulation by IFN-alpha/gamma-mediated Stat1 suppresses anti-HBV T cell response, Liu, LanLan, Hou, Junwei, Xu, Yuxiu, Qin, Lijuan, Liu, Weiwei, Zhang, Han, Li, Yang, Chen, Mi, Deng, Mengmeng, Zhao, Bao, Hu, Jun, Zheng, Huaguo, Li, Changfei, Meng, Songdong, 2020
PD-L1upregulation by IFN-a/r-mediated stat1 suppresses anti-HBV T cell response, Songdong Meng, 2020
A peptide-based inhibitor of gp96 suppresses HBsAg expression and HBV replication by upregulation of p53, Qian, Liyuan, Fan, Hongxia, Ju, Ying, Chen, Lizhao, Li, Xin, Ye, Xin, Luo, Yunjing, Li, Changfei, Meng, Songdong, 2019
Dendritic cells pulsed with placental gp96 promote tumor-reactive immune responses, Zheng, Huaguo, Liu, Lanlan, Zhang, Han, Kan, Fangming, Wang, Shuo, Li, Yang, Tian, Huaqin, Meng, Songdong, 2019
Posttranscriptional upregulation of HER3 by HER2 mRNA induces trastuzumab resistance in breast cancer, Li, Xin, Xu, Yuxiu, Ding, Yun, Li, Changfei, Zhao, Hong, Wang, Jiandong, Meng, Songdong, 2018
CD8(+) T-Cell Response-Associated Evolution of Hepatitis B Virus Core Protein and Disease Progress, Zhang, Yu, Wu, Yan, Deng, Mengmeng, Xu, Dongping, Li, Xiaodong, Xu, Zhihui, Hu, Jun, Zhang, Han, Liu, Kefang, Zhao, Yingze, Gao, Feng, Bi, Shengli, Gao, George F, Zhao, Jingmin, Liu, William J, Meng, Songdong, 2018
Disease Progress-Associated Evolution of Hepatitis B Virus Core Protein Driven By CD8(+) T-Cell Responses, Zhao, Jingmin, Zhang, Yu, Meng, Songdong, 2018
CD8+ T-Cell Responses-Associated Evolution of Hepatitis B Virus Core Protein in Disease Progress, Songdong Meng, 2018
Endogenous Cellular MicroRNAs Mediate Antiviral Defense against Influenza A Virus, Peng, Shanxin, Wang, Jing, Wei, Songtao, Li, Changfei, Zhou, Kai, Hu, Jun, Ye, Xin, Yan, Jinghua, Liu, Wenjun, Gao, George F, Fang, Min, Meng, Songdong, 2018
Hepatitis B core-related antigen (HBcrAg) correlated with HBV serum viral markers and intrahepatic indicators in treatment-naive patients with acute and chronic HBV, Zhang, Yu, Xu, Dongping, Meng, Songdong, Lu, Fengmin, Zhao, JingMin, 2017
Urokinase-type plasminogen activator receptor inhibits apoptosis in triple-negative breast cancer through miR-17/20a suppression of death receptors 4 and 5, Li, Xin, Wu, Bo, Chen, Lizhao, Ju, Ying, Li, Changfei, Meng, Songdong, 2017
Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8(+) T Cell Epitopes and Host MHC, Liu, William J, Lan, Jiaming, Liu, Kefang, Deng, Yao, Yao, Yanfeng, Wu, Shaolian, Chen, Hong, Bao, Lingling, Zhang, Haifeng, Zhao, Min, Wang, Qihui, Han, Lingxia, Chai, Yan, Qi, Jianxun, Zhao, Jincun, Meng, Songdong, Qin, Chuan, Gao, George F, Tan, Wenjie, 2017
Mapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90, Hong, Feng, Rachidi, Saleh Mohammad, Lundgren, Debbie, Han, David, Huang, Xiu, Zhao, Hongyu, Kimura, Yayoi, Hirano, Hisashi, Ohara, Osamu, Udono, Heichiiro, Meng, Songdong, Liu, Bei, Li, Zihai, 2017
CD133表位联合热休克蛋白佐剂疫苗引发抗白血病的免疫应答, 王硕, 范红霞, 李杨, 郑华国, 李鑫, 李长菲, 陈立钊, 鞠莹, 孟颂东, 2017
PTD-fused p53 as a potential antiviral agent directly suppresses HBV transcription and expression, Chu, Xiaoyu, Wu, Bo, Fan, Hongxia, Hou, Junwei, Hao, Junli, Hu, Jun, Wang, Baozhong, Liu, Guangze, Li, Changfei, Meng, Songdong, 2016
Chronic inflammation contributes to the development of hepatocellular carcinoma by decreasing miR-122 levels, Li, Changfei, Deng, Mengmeng, Hu, Jun, Li, Xin, Chen, Lizhao, Ju, Ying, Hao, Junli, Meng, Songdong, 2016
Interaction of Toll-Like Receptors with the Molecular Chaperone Gp96 Is Essential for Its Activation of Cytotoxic T Lymphocyte Response, Liu, Weiwei, Chen, Mi, Li, Xinghui, Zhao, Bao, Hou, Junwei, Zheng, Huaguo, Qiu, Lipeng, Li, Zihai, Meng, Songdong, 2016
Heat shock protein gp96 enhances T cell responses and protective potential to Bacillus Calmette-Guérin vaccine, Songdong Meng, 2016
热休克蛋白gp96 3′UTR作为ceRNA通过miR-642a调控DOHH的表达*, 盛春海, 孙璐, 初骁宇, 李长菲, 孟颂东, 2016
Hepatitis B virus mRNAs functionally sequester let-7a and enhance hepatocellular carcinoma, Deng, Mengmeng, Hou, Junwei, Hu, Jun, Wang, Shuo, Chen, Mi, Chen, Lizhao, Ju, Ying, Li, Changfei, Meng, Songdong

Hepatitis B Virus Immunity Tumor Cancer Vaccine Immunopreparations Research Microbiology Biochemistry

Jin Tang Dong - Southern University of Science and Technology

Ning Jia - Southern University of Science and Technology

Junwei Song - Southern University of Science and Technology

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