Professor | Kai-Xian Chen | Asia Growth Partners

Name	Kai-Xian Chen
Contact Information	kxchen@simm.ac.cn
Language ability	Chinese, English, French
Province	Shanghai

Name

Kai-Xian Chen

Contact Information

kxchen@simm.ac.cn

Language ability

Chinese, English, French

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1985-03 to 1988-06: Visiting Scholar at Institut de Biophysique et Chimie Biophysique, Paris, France 1978-09 to 1985-02: Master's and Ph.D. degrees from Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1962-09 to 1967-08: Bachelor's degree from Fudan University
Work Experience	2014-04 to Present: Director of the Degree Committee at Shanghai Institute of Materia Medica, Chinese Academy of Sciences 2014-03 to Present: Director of the Academic Committee at Shanghai University of Traditional Chinese Medicine 2005-03 to 2014-02: President of Shanghai University of Traditional Chinese Medicine 2005-01 to 2014-03: Director of the Academic Committee at Shanghai Institute of Materia Medica, Chinese Academy of Sciences 2004-08 to 2008-09: Party Secretary at Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 1999-10 to Present: Academician at Chinese Academy of Sciences 1996-04 to 2004-12: Director at Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1988-06 to 1996-04: Associate Researcher, Researcher, Doctoral Supervisor, and Deputy Director at Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1985-03 to 1988-06: Visiting Scholar at Institut de Biophysique et Chimie Biophysique, Paris, France 1978-09 to 1985-02: Master's and Ph.D. degrees from Shanghai Institute of Materia Medica, Chinese Academy of Sciences 1974-03 to 1978-08: Technician at Hunan Institute of Pharmaceutical Industry 1970-05 to 1974-03: Worker and Technician at Central South Pharmaceutical Factory (Hunan Shaoyang), Ministry of Chemical Industry 1968-10 to 1970-05: Squad Leader at Chengxi Lake Military Reclamation Farm, Huoqiu County, Anhui Province 1962-09 to 1967-08: Bachelor's degree from Fudan University
Awards	Zhangjiang 'Leading Talent in Science and Technology' Award (2009): City-level 973 Program Outstanding Research Team (2008): Special Pudong Leading Talent in Independent Innovation (2005): City-level Outstanding Talent in Pudong Development (2003): City-level Top Ten Best Principals (Directors) in Shanghai (2002): City-level Ho Leung Ho Lee Foundation Science and Technology Progress Award (2001): National-level Outstanding Contributor to the '863' Program (2000): National-level Shanghai Science and Technology Progress Award, Third Prize (1999): City-level Chinese Academy of Sciences Natural Science Award, Second Prize (1998): National-level Chinese Academy of Sciences Natural Science Award, Second Prize (1997): National-level Top Ten Science and Technology Elites in Shanghai (1997): City-level Outstanding Young and Middle-aged Expert with Outstanding Contributions, Chinese Academy of Sciences (1994): Institute-level Outstanding Chinese Ph.D. Degree Holder, State Council Academic Degrees Committee (1991): National-level Chinese Academy of Sciences Science and Technology Progress Award, Second Prize (1985): Institute-level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1985-03 to 1988-06: Visiting Scholar at Institut de Biophysique et Chimie Biophysique, Paris, France
1978-09 to 1985-02: Master's and Ph.D. degrees from Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1962-09 to 1967-08: Bachelor's degree from Fudan University

Work Experience

2014-04 to Present: Director of the Degree Committee at Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2014-03 to Present: Director of the Academic Committee at Shanghai University of Traditional Chinese Medicine
2005-03 to 2014-02: President of Shanghai University of Traditional Chinese Medicine
2005-01 to 2014-03: Director of the Academic Committee at Shanghai Institute of Materia Medica, Chinese Academy of Sciences
2004-08 to 2008-09: Party Secretary at Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
1999-10 to Present: Academician at Chinese Academy of Sciences
1996-04 to 2004-12: Director at Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1988-06 to 1996-04: Associate Researcher, Researcher, Doctoral Supervisor, and Deputy Director at Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1985-03 to 1988-06: Visiting Scholar at Institut de Biophysique et Chimie Biophysique, Paris, France
1978-09 to 1985-02: Master's and Ph.D. degrees from Shanghai Institute of Materia Medica, Chinese Academy of Sciences
1974-03 to 1978-08: Technician at Hunan Institute of Pharmaceutical Industry
1970-05 to 1974-03: Worker and Technician at Central South Pharmaceutical Factory (Hunan Shaoyang), Ministry of Chemical Industry
1968-10 to 1970-05: Squad Leader at Chengxi Lake Military Reclamation Farm, Huoqiu County, Anhui Province
1962-09 to 1967-08: Bachelor's degree from Fudan University

Awards

Zhangjiang 'Leading Talent in Science and Technology' Award (2009): City-level
973 Program Outstanding Research Team (2008): Special
Pudong Leading Talent in Independent Innovation (2005): City-level
Outstanding Talent in Pudong Development (2003): City-level
Top Ten Best Principals (Directors) in Shanghai (2002): City-level
Ho Leung Ho Lee Foundation Science and Technology Progress Award (2001): National-level
Outstanding Contributor to the '863' Program (2000): National-level
Shanghai Science and Technology Progress Award, Third Prize (1999): City-level
Chinese Academy of Sciences Natural Science Award, Second Prize (1998): National-level
Chinese Academy of Sciences Natural Science Award, Second Prize (1997): National-level
Top Ten Science and Technology Elites in Shanghai (1997): City-level
Outstanding Young and Middle-aged Expert with Outstanding Contributions, Chinese Academy of Sciences (1994): Institute-level
Outstanding Chinese Ph.D. Degree Holder, State Council Academic Degrees Committee (1991): National-level
Chinese Academy of Sciences Science and Technology Progress Award, Second Prize (1985): Institute-level

Areas of Focus	Computer-Aided Drug Design Traditional Chinese Medicine
Publications	In silico ADME/T modelling for rational drug design, Kai-Xian Chen, 2015 Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms., Kai-Xian Chen, 2015 In Silico target fishing: addressing a 'Big Data' problem by ligand-based similarity rankings with data fusion, Kai-Xian Chen, 2014 Estimation of acute oral toxicity in rat using local lazy learning, Kai-Xian Chen, 2014 In Silico Site of Metabolism (SOM) Prediction for Human UGT-Catalyzed Reactions., Kai-Xian Chen, 2014 Combinatorial pharmacophore modeling of organic cation transporter 2 (OCT2) inhibitors: insights into multiple inhibitory mechanisms., Kai-Xian Chen, 2013

Areas of Focus

Computer-Aided Drug Design
Traditional Chinese Medicine

Publications

In silico ADME/T modelling for rational drug design, Kai-Xian Chen, 2015
Combinatorial Pharmacophore Modeling of Multidrug and Toxin Extrusion Transporter 1 Inhibitors: a Theoretical Perspective for Understanding Multiple Inhibitory Mechanisms., Kai-Xian Chen, 2015
In Silico target fishing: addressing a 'Big Data' problem by ligand-based similarity rankings with data fusion, Kai-Xian Chen, 2014
Estimation of acute oral toxicity in rat using local lazy learning, Kai-Xian Chen, 2014
In Silico Site of Metabolism (SOM) Prediction for Human UGT-Catalyzed Reactions., Kai-Xian Chen, 2014
Combinatorial pharmacophore modeling of organic cation transporter 2 (OCT2) inhibitors: insights into multiple inhibitory mechanisms., Kai-Xian Chen, 2013

Drug Design Computational Chemistry Pharmacophore Molecular Modeling Adme/T Toxicity Prediction Target Fishing Big Data Ligand-Based Data Fusion

Wei Jiao - University of Chinese Academy of Sciences

Qiang Shao - University of Chinese Academy of Sciences

Kunqian Yu - University of Chinese Academy of Sciences

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