Professor | Guoyuan Chen | Asia Growth Partners

Name	Guoyuan Chen
Contact Information	chenguoy@sibcb.ac.cn
Language ability	Chinese, English
Province	Shanghai

Name

Guoyuan Chen

Contact Information

chenguoy@sibcb.ac.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2002-09--2010-01 PhD: Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences 1996-09--2000-07 Bachelor's: Department of Biology, Zhejiang University
Work Experience	2012-07~2012-12 - Nanjing University Model Animal Research Institute National Mutant Mouse Resource Library - Visiting Scholar 2011-11~Present - Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Regional Manager/Deputy Director of Animal Experiment Technology Platform 2010-10~2011-11 - National Heart, Lung, and Blood Institute, NIH - Visiting Scholar
Awards	Excellent Paper in 'Experimental Animals and Comparative Medicine' (2022): First Prize, Special Excellent Reviewer in 'Experimental Animals and Comparative Medicine' (2020): First Prize, Special Excellent Paper in East China Experimental Animal Science Academic Annual Conference (2018): First Prize, Provincial

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2002-09--2010-01 PhD: Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
1996-09--2000-07 Bachelor's: Department of Biology, Zhejiang University

Work Experience

2012-07~2012-12 - Nanjing University Model Animal Research Institute National Mutant Mouse Resource Library - Visiting Scholar
2011-11~Present - Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Regional Manager/Deputy Director of Animal Experiment Technology Platform
2010-10~2011-11 - National Heart, Lung, and Blood Institute, NIH - Visiting Scholar

Awards

Excellent Paper in 'Experimental Animals and Comparative Medicine' (2022): First Prize, Special
Excellent Reviewer in 'Experimental Animals and Comparative Medicine' (2020): First Prize, Special
Excellent Paper in East China Experimental Animal Science Academic Annual Conference (2018): First Prize, Provincial

Areas of Focus	Animal Models and Small Animal Imaging
Publications	MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease, Lu Geng, Hexige Saiyin, Wenqing Gao, Yuanyuan Li, Guoyuan Chen, Jixi Li, 2023 《动物研究：体内实验报告》即ARRIVE 2.0指南的解释和阐述（二）, 陈国元, 卢晓, 白玉, 于灵芝, 乔颖, 王剑, 卢今, 刘晓宇, 卢选成, 高静, 李垚, 庞万勇, 2023 动物实验研究报告的国际指南ARRIVE 2.0介绍及期刊实施计划, 张俊彦, 刘晓宇, 李垚, 陈国元, 卢晓, 白玉, 卢选成, 庞万勇, 吴宝金, 2023 大鼠肠系膜淋巴液持续引流新方法的初步建立, 张笑瑞, 曹静, 吴倩倩, 康康, 陈国元, 吴宝金, 2022 不同剂型普罗布考对大鼠肠系膜淋巴转运及药代动力学的影响, 张笑瑞, 曹静, 吴倩倩, 刘季俊, 陈国元, 吴宝金, 2022 实验材料检测在SPF级实验小鼠质量控制中的应用, 陈国元, 康康, 李晓娴, 纪文韬, 张金梅, 冯延花, 田倩莹, 吴宝金, 2021 屏障动物房书虱爆发、处置与风险评估, 张金梅, 康康, 陈国元, 张笑瑞, 唐蔚, 朱怡琴, 吴宝金, 2019 Functional silencing of HSD17B2 in prostate cancer promotes disease progression, Xiaomei Gao, Charles Dai, Shengsong Huang, Jingjie Tang, Guoyuan Chen, Jianneng Li, Ziqi Zhu, Xuyou Zhu, Shuirong Zhou, Yuanyuan Gao, Zemin Hou, Zijun Fang, Chengdang Xu, Jianyang Wang, Denglong Wu, Nima Sharifi, Zhenfei Li, 2018 HIV-Tat-Mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenicity of Hepatoma Cells, Chen, Guangming, Da, Liang, Wang, Hongfei, Xu, Ying, Chen, Guoyuan, Sun, Chengfu, Wang, Leiming, Zhao, Jing, Zhang, Fang, Feng, Jian, Wang, Yifei, Tiollais, Pierre, Li, Tsaiping, Zhao, Mujun, 2011 C-terminal amino acids 290-328 of LPTS/PinX1 confer telomerase inhibition, Chen, Guoyuan, Da, Liang, Xu, Ying, Xu, Mafei, Song, Li, Li, Tsaiping, Zhao, Mujun, 2010 Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length, Song, H, Li, YL, Chen Guoyuan, Xing, Z, Zhao, J, Zhao, MJ, 2004

Areas of Focus

Animal Models and Small Animal Imaging

Publications

MLKL deficiency alleviates neuroinflammation and motor deficits in the α-synuclein transgenic mouse model of Parkinson's disease, Lu Geng, Hexige Saiyin, Wenqing Gao, Yuanyuan Li, Guoyuan Chen, Jixi Li, 2023
《动物研究：体内实验报告》即ARRIVE 2.0指南的解释和阐述（二）, 陈国元, 卢晓, 白玉, 于灵芝, 乔颖, 王剑, 卢今, 刘晓宇, 卢选成, 高静, 李垚, 庞万勇, 2023
动物实验研究报告的国际指南ARRIVE 2.0介绍及期刊实施计划, 张俊彦, 刘晓宇, 李垚, 陈国元, 卢晓, 白玉, 卢选成, 庞万勇, 吴宝金, 2023
大鼠肠系膜淋巴液持续引流新方法的初步建立, 张笑瑞, 曹静, 吴倩倩, 康康, 陈国元, 吴宝金, 2022
不同剂型普罗布考对大鼠肠系膜淋巴转运及药代动力学的影响, 张笑瑞, 曹静, 吴倩倩, 刘季俊, 陈国元, 吴宝金, 2022
实验材料检测在SPF级实验小鼠质量控制中的应用, 陈国元, 康康, 李晓娴, 纪文韬, 张金梅, 冯延花, 田倩莹, 吴宝金, 2021
屏障动物房书虱爆发、处置与风险评估, 张金梅, 康康, 陈国元, 张笑瑞, 唐蔚, 朱怡琴, 吴宝金, 2019
Functional silencing of HSD17B2 in prostate cancer promotes disease progression, Xiaomei Gao, Charles Dai, Shengsong Huang, Jingjie Tang, Guoyuan Chen, Jianneng Li, Ziqi Zhu, Xuyou Zhu, Shuirong Zhou, Yuanyuan Gao, Zemin Hou, Zijun Fang, Chengdang Xu, Jianyang Wang, Denglong Wu, Nima Sharifi, Zhenfei Li, 2018
HIV-Tat-Mediated Delivery of an LPTS Functional Fragment Inhibits Telomerase Activity and Tumorigenicity of Hepatoma Cells, Chen, Guangming, Da, Liang, Wang, Hongfei, Xu, Ying, Chen, Guoyuan, Sun, Chengfu, Wang, Leiming, Zhao, Jing, Zhang, Fang, Feng, Jian, Wang, Yifei, Tiollais, Pierre, Li, Tsaiping, Zhao, Mujun, 2011
C-terminal amino acids 290-328 of LPTS/PinX1 confer telomerase inhibition, Chen, Guoyuan, Da, Liang, Xu, Ying, Xu, Mafei, Song, Li, Li, Tsaiping, Zhao, Mujun, 2010
Human MCRS2, a cell-cycle-dependent protein, associates with LPTS/PinX1 and reduces the telomere length, Song, H, Li, YL, Chen Guoyuan, Xing, Z, Zhao, J, Zhao, MJ, 2004

Animal Models Small Animal Imaging Biomedical Research Transgenic Mice Neuroinflammation Parkinson'S Disease Telomerase Inhibition Cancer Research Molecular Biology Cell Biology

Zhang Peng - Wuhan University

Song Wu - Wuhan University

Yajie Wang - Wuhan University

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