Areas of Focus
- Drug Chemistry
- Organic Chemistry
Work Experience
- 2016-03~Present - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Researcher
- 2012-07~2016-02 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Associate Researcher
- 2009-12~2012-07 - Scripps Research Institute, USA - Research Assistant
- 2007-12~2009-12 - University of Texas, USA - Postdoctoral Researcher
Academic Background & Achievements
- 2004-09--2007-07 Ph.D.: Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences
- 2001-09--2004-07 Master's: Nankai University
- 1997-09--2001-07 Bachelor's: Nanchang University
Publications
- Palladium-Catalyzed Directed Carbon–Carbon Bond Activation of Aryl Nitriles for Cyano Transfer, Hui-Xiong Dai, 2024
- Palladium-Catalyzed Deuteration of Arylketone Oxime Ethers, Hui-Xiong Dai, 2024
- Construction of thiolated methylene oxindoles via decarbonylative carbocyclization of thioester tethered alkyne, Hui-Xiong Dai, 2024
- Total Synthesis of Syringin and Its Natural Analogues via C–C Bond Activation of Aryl Ketones, Hui-Xiong Dai, 2023
- Construction of Chalcogenated Methylene Chroman-3-ones via Palladium-Catalyzed Carbocyclization, Hui-Xiong Dai, 2023
- Construction of Indole-Fused Seven- and Eight-Membered Azaheterocycles via a Tandem Pd/NBE-Catalyzed Decarbonylation and Dual C–H Activation Sequence, Hui-Xiong Dai, 2023
- Dual ligands relay-promoted transformation of unstrained ketones to polyfluoroarenes and nitriles, Hui-Xiong Dai, 2023
- Construction of polysubstituted pentafulvenes via palladium-catalyzed deacetylation of enones, Hui-Xiong Dai, 2023
- Fused-ring β-pyrones from intramolecular C–H activation and their lipids-lowering activity associated with LXR-IDOL-LDLR axis regulation, Hui-Xiong Dai, 2022
- Construction of Aza-spiro4,5indole Scaffolds via Rhodium-Catalyzed Regioselective C(4)–H Activation of Indole, Hui-Xiong Dai, 2022
- Functionalized styrene synthesis via palladium-catalyzed C-C cleavage of aryl ketones, Hui-Xiong Dai, 2022
- Enones as Alkenyl Reagents via Ligand-Promoted C-C Bond Activation, Hui-Xiong Dai, 2022
- Rhodium-Catalyzed C-H Activation of Indoles for the Construction of Spiroindole Scaffolds, Hui-Xiong Dai, 2022
- Homologation of aryl ketones to long-chain ketones and aldehydes via C–C bond cleavage, Hui-Xiong Dai, 2022
- Palladium-Catalyzed Alkynylation of Enones with Alkynylsilanes via C-C Bond Activation, Hui-Xiong Dai, 2022
- Palladium-catalyzed diarylative dearomatization of indoles with aryl thioesters, Hui-Xiong Dai, 2021
- Construction of 2-alkynyl aza-spiro4,5indole scaffolds via sequential C-H activations for modular click chemistry libraries, Hui-Xiong Dai, 2021
- Copper-mediated ortho C-H primary amination of anilines, Hui-Xiong Dai, 2021
- C3-Arylation of indoles with aryl ketones via C-C/C-H activations, Hui-Xiong Dai, 2021
- Palladium/Norbornene-Catalyzed Decarbonylative Difunctionalization of Thioesters, Hui-Xiong Dai, 2021
- Pd-Catalyzed Asymmetric Dearomatization of Indoles via Decarbonylative Heck-Type Reaction of Thioesters, Hui-Xiong Dai, 2021
- Mizoroki-Heck Reaction of Unstrained Aryl Ketones via Ligand-Promoted C-C Bond Olefination, Hui-Xiong Dai, 2021
- Ligand-Promoted Alkynylation of Aryl Ketones: A Practical Tool for Structural Diversity in Drugs and Natural Products, Hui-Xiong Dai, 2021
- Copper-Mediated ortho-C-H Amination Using DMF as the Amine Source, Hui-Xiong Dai, 2021
- Enones as Alkenyl Reagents via Ligand-Promoted C-C Bond Activation, Hui-Xiong Dai, 2021
- Arylketones as Aryl Donors in Palladium-Catalyzed Suzuki-Miyaura Couplings, Hui-Xiong Dai, 2021
- Pd-Catalyzed Asymmetric Acyl-Carbamoylation of an Alkene to Construct an alpha-Quaternary Chiral Cycloketone, Hui-Xiong Dai, 2021
- Copper-mediated CsbndH thiolation of (hetero)arenes using weakly coordinating directing group, Hui-Xiong Dai, 2020
- Palladium-catalyzed meta-C—H bond iodination of arenes with I2, Hui-Xiong Dai, 2020
- Palladium-catalyzed fluoroacylation of (Hetero)arylboronic acid with fluorothioacetates at ambient temperature, Hui-Xiong Dai, 2020
- Copper-Catalyzed Oxalamide-Directed ortho-C-H Amination of Anilines with Alkylamines, Hui-Xiong Dai, 2020
- Synthesis of Trifluoromethylarenes via Nickel-Mediated C-O Bond Activation of Phenol Derivatives, Hui-Xiong Dai, 2020
- Copper-mediated C-H thiolation of (hetero)arenes using weakly coordinating directing group, Hui-Xiong Dai, 2020
- Copper mediated C(sp(2))-H amination and hydroxylation of phosphinamides, Hui-Xiong Dai, 2020
- Palladium-catalyzed meta-CsbndH bond iodination of arenes with I2, Hui-Xiong Dai, 2020
- Cu(II) Mediated beta-C-H Alkynylation of Acrylamides with Terminal Alkynes, Hui-Xiong Dai, 2020
- Palladium-Catalyzed, Copper(I)-Promoted Methoxycarbonylation of Arylboronic Acids with O-Methyl S-Aryl Thiocarbonates, Hui-Xiong Dai, 2020
- Synthesis of Trifluoromethylarenes via Nickel-Mediated C-O Bond Activation of Phenol Derivatives, Hui-Xiong Dai, 2020
- Cu(II)-Mediated beta-C-H Alkynylation of Acrylamides with Terminal Alkynes, Hui-Xiong Dai, 2020
- Transformations of Aryl Ketones via Ligand-Promoted C-C Bond Activation, Hui-Xiong Dai, 2020
- Synthesis of Axially Chiral Olefin-Oxazoline Ligands via Pd-Catalyzed Multiple C-H Functionalization, Hui-Xiong Dai, 2020
- Remote Para-C-H Acetoxylation of Electron-Deficient Arenes, Hui-Xiong Dai, 2019
- Palladium-catalyzed intramolecular CsbndH acylation of indoles with thioester, Hui-Xiong Dai, 2019
- Copper-catalyzedα-selective C–H trifluoromethylation of acrylamides with TMSCF3, Hui-Xiong Dai, 2019
- Copper-catalyzed alpha-selective C-H trifluoromethylation of acrylamides with TMSCF3, Hui-Xiong Dai, 2019
- coppercatalyzedselectivechtrifluoromethylationofacrylamideswithtmscf3, Hui-Xiong Dai, 2019
- Palladium-Catalyzed Remote meta-C-H Bond
Awards
- Shanghai Outstanding Young Academic Leader (2019): City-level
- Shanghai Youth May Fourth Medal in Science and Technology System (2019): City-level
- Lu Jiaxi Young Talent Award, Chinese Academy of Sciences (2015): Institute-level
- Thieme Chemistry Journals Award (2015): Other
- Member of Youth Innovation Promotion Association, Chinese Academy of Sciences (2014): Institute-level
