Areas of Focus
- Organometallic Chemistry
- Medicinal Chemistry
Work Experience
- 2013-12 to 2016-10 - The Scripps Research Institute - Research Assistant
- 2013-08 to 2013-10 - Heidelberg University - Research Assistant
- 2010-09 to 2013-08 - Heidelberg University - PhD
- 2007-08 to 2010-07 - Dalian University of Technology - Master's
- 2003-09 to 2007-07 - Liaoning University of Science and Technology - Bachelor's
Academic Background & Achievements
- 2010-09 to 2013-08 PhD: Heidelberg University
- 2007-08 to 2010-07 Master's: Dalian University of Technology
- 2003-09 to 2007-07 Bachelor's: Liaoning University of Science and Technology
Publications
- Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance, Yang Weibo, 2023
- Multicomponent coupling and macrocyclization enabled by Rh(III)-catalyzed dual C-H activation: Macrocyclic oxime inhibitor of influenza H1N1, Yang Weibo, 2023
- Rhodium(III)-Catalyzed C-H/O-2 Dual Activation and Macrocyclization: Synthesis and Evaluation of Pyrido2,1-aisoindole Grafted Macrocyclic Inhibitors for Influenza H1N1, Yang Weibo, 2023
- A selective PPM1A inhibitor activates autophagy to restrict the survival of Mycobacterium tuberculosis, Yang Weibo, 2022
- Natural scaffolds-inspired synthesis of CF_(3)-substituted macrolides enabled by Rh-catalyzed C–H alkylation macrocyclization, Yang Weibo, 2022
- Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp(3))-H olefination mediated by donor/donor carbenes, Yang Weibo, 2021
- Rh-Catalyzed cascade C-H activation/C-C cleavage/cyclization of carboxylic acids with cyclopropanols, Yang Weibo, 2021
- Rh-Catalyzed C-H alkylation enabling modular synthesis of CF3-substituted benzannulated macrocyclic inhibitors of B cell responses, Yang Weibo, 2021
- Pd-Catalyzed Decarboxylative Olefination: Stereoselective Synthesis of Polysubstituted Butadienes and Macrocyclic P-glycoprotein Inhibitors, Yang Weibo, 2020
- Manipulating the Click Reactivity of Dibenzoazacyclooctynes: From Azide Click Component to Caged Acylation Reagent by Silver Catalysis, Yang Weibo, 2020
- A modular biomimetic strategy for the synthesis of macrolide P-glycoprotein inhibitors via Rh-catalyzed C-H activation, Yang Weibo, 2020
- Vinylethylene Carbonates as alpha,beta-Unsaturated Aldehyde Surrogates for Regioselective 3+3 Cycloaddition, Yang Weibo, 2019
- Diversity-Orientated Stereoselective Synthesis through Pd-Catalyzed Switchable Decarboxylative C-N/C-S Bond Formation in Allylic Surrogates, Yang Weibo, 2018
- Divergent synthesis of N-heterocycles by Pd-catalyzed controllable cyclization of vinylethylene carbonates, Yang Weibo, 2018
- Pd-Catalyzed Three-Component Domino Reaction of Vinyl Benzoxazinanones for Regioselective and Stereoselective Synthesis of Allylic Sulfone-Containing Amino Acid Derivatives, Yang Weibo, 2018
- Orchestrated Triple C-H Activation Reactions Using Two Directing Groups: Rapid Assembly of Complex Pyrazoles, Yang Weibo, 2015
- Mechanistic insights into the gold chemistry of allenes, Yang Weibo, 2014
- Dehydrogenative Meyer-Schuster-Like Rearrangement: A Gold-Catalyzed Reaction Generating an Alkyne, Yang Weibo, 2014
- Gold-Catalyzed Formal 1,6-Acyloxy Migration Leading to 3,4-Disubstituted Pyrrolidin-2-ones, Yang Weibo, 2013
- In Situ Generation of Nucleophilic Allenes by the Gold-Catalyzed Rearrangement of Propargylic Esters for the Highly Diastereoselective Formation of Intermolecular C(sp(3))-C(sp(2)) Bonds, Yang Weibo, 2013
- Gold(I)-Catalyzed Formation of Benzobfurans from 3-Silyloxy-1,5-enynes, Yang Weibo, 2011
- Marine furanocembranoids-inspired macrocycles enabled by Pd-catalyzed unactivated C(sp3)-H olefination mediated by donor/donor carbenes, Yang Weibo
Awards
- 2023: Leading Goose Award, University of Chinese Academy of Sciences
- 2023: 18th West Lake Talent Program
- 2023: Outstanding Party Worker, Shanghai Institute of Materia Medica
- 2023: Outstanding Academic Leader, Shanghai
- 2023: Pearl Elite Talent, Pudong New Area
- 2023: Leading Project of the Oriental Talent Program (16th batch of Shanghai Leading Talents)
- 2019: Shanghai Youth Science and Technology Star
- 2018: Outstanding Mentor, Chinese Academy of Sciences
- 2017: Shanghai Youth Top Talent
- 2016: Thieme Chemistry Journals Award
