Professor | Xin Fang | Asia Growth Partners

Name	Xin Fang
Contact Information	xinfang@mail.kib.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Xin Fang

Contact Information

xinfang@mail.kib.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2005-03--2009-01 PhD: Kunming Institute of Botany, Chinese Academy of Sciences 2001-09--2004-03 Master's Degree: College of Materials and Chemical Engineering, Zhejiang University 1992-09--1996-06 Bachelor's Degree: Department of Fiber Materials, Beijing Institute of Fashion Technology
Work Experience	2023-06~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher 2018-02~2023-05 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher 2017-01~2018-01 - Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Assistant Researcher 2014-01~2016-12 - Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Postdoctoral Researcher 2010-01~2013-12 - Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Postdoctoral Researcher
Awards	Research on Plant Chemical Defense Substances and New Pesticide Lead Compounds (2013): First Prize, Provincial Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2005-03--2009-01 PhD: Kunming Institute of Botany, Chinese Academy of Sciences
2001-09--2004-03 Master's Degree: College of Materials and Chemical Engineering, Zhejiang University
1992-09--1996-06 Bachelor's Degree: Department of Fiber Materials, Beijing Institute of Fashion Technology

Work Experience

2023-06~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
2018-02~2023-05 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
2017-01~2018-01 - Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Assistant Researcher
2014-01~2016-12 - Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Postdoctoral Researcher
2010-01~2013-12 - Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences - Postdoctoral Researcher

Awards

Research on Plant Chemical Defense Substances and New Pesticide Lead Compounds (2013): First Prize, Provincial Level

Areas of Focus	Discovery of highly active natural product small molecules Biosynthesis of important plant secondary metabolites Mechanism of key enzymes in metabolic pathways
Publications	Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds, Jia-Ling Lin, Xin Fang, Jian-Xu Li, Zhi-Wen Chen, Wen-Kai Wu, Xiao-Xiang Guo, Ning-Jing Liu, Jia-Fa Huang, Fang-Yan Chen, Ling-Jian Wang, Baofu Xu, Cathie Martin, Xiao-Ya Chen, Jin-Quan Huang, 2023 A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, Jiao-Jiao Song, Xin Fang, Chen-Yi Li, Yan Jiang, Jian-Xu Li, Sheng Wu, Juan Guo, Yan Liu, Hang Fan, Yan-Bo Huang, Yu-Kun Wei, Yu Kong, Qing Zhao, Jing-Jing Xu, Yong-Hong Hu, Xiao-Ya Chen, Lei Yang, 2022 Chemical constituents of Euphorbia peplus, Min, XiaoYan, Chen, YanNi, Li, DongMei, Mu, QiuYan, Zhang, ZunTing, Fang, Xin, 2021 1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, Huang, JinQuan, Li, DongMei, Li, JianXu, Lin, JiaLing, Tian, Xiu, Wang, LingJian, Chen, XiaoYa, Fang, Xin, 2021 Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway, Chen, YanNi, Ding, Xiao, Li, DongMei, Sun, Mao, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2021 Side Products of Recombinant Amorpha-4,11-diene Synthase and Their Effect on Microbial Artemisinin Production, Huang, JinQuan, Li, DongMei, Tian, Xiu, Lin, JiaLing, Yang, Lei, Xu, JingJing, Fang, Xin, 2021 Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway, YanNi Chen, Xiao Ding, DongMei Li, QingYun Lu, Shuai Liu, YingYao Li, YingTong Di, Xin Fang, XiaoJiang Hao, 2021 Amorpha-4,11-diene synthase: a key enzyme in artemisinin biosynthesis and engineering, Xin Fang, 2021 Aromatization of natural products by a specialized detoxification enzyme, Huang, JinQuan, Fang, Xin, Tian, Xiu, Chen, Ping, Lin, JiaLing, Guo, XiaoXiang, Li, JianXu, Fan, Zhen, Song, WeiMeng, Chen, FangYan, Ahati, Ruzha, Wang, LingJian, Zhao, Qing, Martin, Cathie, Chen, XiaoYa, 2020 Three new diterpenoids form Euphorbia peplus, Xin Fang, 2020 Three new diterpenoids from Euphorbia peplus, Yang Lei, 2020 Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis, Chen, YanNi, Ding, Xiao, Lu, QingYun, Li, DongMei, Li, BoTing, Liu, Shuai, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2020 RES transformation for biosynthesis and detoxification, Huang, JinQuan, Lin, JiaLing, Guo, XiaoXiang, Tian, Xiu, Tian, Ye, Shangguan, XiaoXia, Wang, LingJian, Fang, Xin, Chen, XiaoYa, 2020 A gossypol biosynthetic intermediate disturbs plant defense response, Xin Fang, 2019 Characterization of gossypol biosynthetic pathway, Tian, Xiu, Ruan, JuXin, Huang, JinQuan, Yang, ChangQing, Fang, Xin, Chen, ZhiWen, Hong, Hui, Wang, LingJian, Mao, YingBo, Lu, Shan, Zhang, TianZhen, Chen, XiaoYa, 2018 Characterization of Arabidopsis thaliana hydroxyphenylpyruvate reductases in the tyrosine conversion metabolic pathway, Xin Fang, 2018 Engineering purple rice for human health, Fang, Xin, Mao, Yingbo, Chen, Xiaoya, 2018 A brief view of international conference on plant cell wall biology 2017, Fang, Xin, Sun, Juncong, Leng, Bing, Sheng, Guoan, Huang, Jirong, Qi, Xiaoquan, Chen, Xiaoya, Li, Laigeng, 2017 Branching Out, BIRMOSER ANDREAS, 2017 Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining, Fang, Xin, Li, ChenYi, Yang, Yue, Cui, MengYing, Chen, XiaoYa, Yang, Lei, 2017 Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance, Mao, YingBo, Liu, YaoQian, Chen, DianYang, Chen, FangYan, Fang, Xin, Hong, GaoJie, Wang, LingJian, Wang, JiaWei, Chen, XiaoYa, 2017 Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, Fang, Xin, Li, JianXu, Huang, JinQuan, Xiao, YouLi, Zhang, Peng, Chen, XiaoYa, 2017 Unprecedented Quassinoids with Promising Biological Activities from Harrisonia perforate, Xin Fang, 2015 Isolation and Asymmetric Total Synthesis of Perforanoid A, Shen Yuemao, 2015

Areas of Focus

Discovery of highly active natural product small molecules
Biosynthesis of important plant secondary metabolites
Mechanism of key enzymes in metabolic pathways

Publications

Dirigent gene editing of gossypol enantiomers for toxicity-depleted cotton seeds, Jia-Ling Lin, Xin Fang, Jian-Xu Li, Zhi-Wen Chen, Wen-Kai Wu, Xiao-Xiang Guo, Ning-Jing Liu, Jia-Fa Huang, Fang-Yan Chen, Ling-Jian Wang, Baofu Xu, Cathie Martin, Xiao-Ya Chen, Jin-Quan Huang, 2023
A 2-oxoglutarate-dependent dioxygenase converts dihydrofuran to furan in Salvia diterpenoids, Jiao-Jiao Song, Xin Fang, Chen-Yi Li, Yan Jiang, Jian-Xu Li, Sheng Wu, Juan Guo, Yan Liu, Hang Fan, Yan-Bo Huang, Yu-Kun Wei, Yu Kong, Qing Zhao, Jing-Jing Xu, Yong-Hong Hu, Xiao-Ya Chen, Lei Yang, 2022
Chemical constituents of Euphorbia peplus, Min, XiaoYan, Chen, YanNi, Li, DongMei, Mu, QiuYan, Zhang, ZunTing, Fang, Xin, 2021
1,10/1,11-Cyclization catalyzed by diverged plant sesquiterpene synthases is dependent on a single residue, Huang, JinQuan, Li, DongMei, Li, JianXu, Lin, JiaLing, Tian, Xiu, Wang, LingJian, Chen, XiaoYa, Fang, Xin, 2021
Diterpenoids with an unprecedented ring system from Euphorbia peplus and their activities in the lysosomal-autophagy pathway, Chen, YanNi, Ding, Xiao, Li, DongMei, Sun, Mao, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2021
Side Products of Recombinant Amorpha-4,11-diene Synthase and Their Effect on Microbial Artemisinin Production, Huang, JinQuan, Li, DongMei, Tian, Xiu, Lin, JiaLing, Yang, Lei, Xu, JingJing, Fang, Xin, 2021
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway, YanNi Chen, Xiao Ding, DongMei Li, QingYun Lu, Shuai Liu, YingYao Li, YingTong Di, Xin Fang, XiaoJiang Hao, 2021
Amorpha-4,11-diene synthase: a key enzyme in artemisinin biosynthesis and engineering, Xin Fang, 2021
Aromatization of natural products by a specialized detoxification enzyme, Huang, JinQuan, Fang, Xin, Tian, Xiu, Chen, Ping, Lin, JiaLing, Guo, XiaoXiang, Li, JianXu, Fan, Zhen, Song, WeiMeng, Chen, FangYan, Ahati, Ruzha, Wang, LingJian, Zhao, Qing, Martin, Cathie, Chen, XiaoYa, 2020
Three new diterpenoids form Euphorbia peplus, Xin Fang, 2020
Three new diterpenoids from Euphorbia peplus, Yang Lei, 2020
Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis, Chen, YanNi, Ding, Xiao, Lu, QingYun, Li, DongMei, Li, BoTing, Liu, Shuai, Yang, Lei, Zhang, Yu, Di, YingTong, Fang, Xin, Hao, XiaoJiang, 2020
RES transformation for biosynthesis and detoxification, Huang, JinQuan, Lin, JiaLing, Guo, XiaoXiang, Tian, Xiu, Tian, Ye, Shangguan, XiaoXia, Wang, LingJian, Fang, Xin, Chen, XiaoYa, 2020
A gossypol biosynthetic intermediate disturbs plant defense response, Xin Fang, 2019
Characterization of gossypol biosynthetic pathway, Tian, Xiu, Ruan, JuXin, Huang, JinQuan, Yang, ChangQing, Fang, Xin, Chen, ZhiWen, Hong, Hui, Wang, LingJian, Mao, YingBo, Lu, Shan, Zhang, TianZhen, Chen, XiaoYa, 2018
Characterization of Arabidopsis thaliana hydroxyphenylpyruvate reductases in the tyrosine conversion metabolic pathway, Xin Fang, 2018
Engineering purple rice for human health, Fang, Xin, Mao, Yingbo, Chen, Xiaoya, 2018
A brief view of international conference on plant cell wall biology 2017, Fang, Xin, Sun, Juncong, Leng, Bing, Sheng, Guoan, Huang, Jirong, Qi, Xiaoquan, Chen, Xiaoya, Li, Laigeng, 2017
Branching Out, BIRMOSER ANDREAS, 2017
Identification of a Novel (-)-5-Epieremophilene Synthase from Salvia miltiorrhiza via Transcriptome Mining, Fang, Xin, Li, ChenYi, Yang, Yue, Cui, MengYing, Chen, XiaoYa, Yang, Lei, 2017
Jasmonate response decay and defense metabolite accumulation contributes to age-regulated dynamics of plant insect resistance, Mao, YingBo, Liu, YaoQian, Chen, DianYang, Chen, FangYan, Fang, Xin, Hong, GaoJie, Wang, LingJian, Wang, JiaWei, Chen, XiaoYa, 2017
Systematic identification of functional residues of Artemisia annua amorpha-4,11-diene synthase, Fang, Xin, Li, JianXu, Huang, JinQuan, Xiao, YouLi, Zhang, Peng, Chen, XiaoYa, 2017
Unprecedented Quassinoids with Promising Biological Activities from Harrisonia perforate, Xin Fang, 2015
Isolation and Asymmetric Total Synthesis of Perforanoid A, Shen Yuemao, 2015

Natural Products Small Molecules Biosynthesis Secondary Metabolites Enzymes Metabolic Pathways Plant Chemistry Molecular Biology Biochemistry Genomics

Jin Tang Dong - Southern University of Science and Technology

Ning Jia - Southern University of Science and Technology

Ji Yang - Southern University of Science and Technology

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