Professor | Yongzhuo Huang | Asia Growth Partners

Name	Yongzhuo Huang
Contact Information	{'en': 'Email: yzhuangATmail.shcnc.ac.cn\\nPhone: 021-20231000-1401', 'zh': '电子邮件：yzhuangATmail.shcnc.ac.cn\\n联系电话：021-20231000-1401', 'de': 'E-Mail: yzhuangATmail.shcnc.ac.cn\\nTelefon: 021-20231000-1401'}
Language ability	English, Chinese
Province	Shanghai

Name

Yongzhuo Huang

Contact Information

{'en': 'Email: yzhuangATmail.shcnc.ac.cn\\nPhone: 021-20231000-1401', 'zh': '电子邮件：yzhuangATmail.shcnc.ac.cn\\n联系电话：021-20231000-1401', 'de': 'E-Mail: yzhuangATmail.shcnc.ac.cn\\nTelefon: 021-20231000-1401'}

Language ability

English, Chinese

Province

Shanghai

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	Zhejiang University - Graduate Zhejiang University - Doctorate 2008-2010 Senior Research Fellow, University of Michigan College of Pharmacy 2005-2008 Research Fellow, University of Michigan College of Pharmacy
Work Experience	2010 - Present - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Researcher, Group Leader

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

Zhejiang University - Graduate
Zhejiang University - Doctorate
2008-2010 Senior Research Fellow, University of Michigan College of Pharmacy
2005-2008 Research Fellow, University of Michigan College of Pharmacy

Work Experience

2010 - Present - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Researcher, Group Leader

Areas of Focus	Transdermal New Formulations and Technologies Biotechnology Drug Delivery Systems Environmentally Responsive Tumor Molecular Probes and Imaging
Publications	Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis, Tang, Yisi, Liang, Jianming, Wu, Aihua, Chen, Yingzhi, Zhao, Pengfei, Lin, Tingting, Zhang, Meng, Xu, Qin, Wang, Jianxin, Huang, Yongzhuo, 2020 Improved Protein Toxin Delivery Based on ATTEMPTS Systems, Chen, Yingzhi, Zhang, Meng, Min, Kyoung Ah, Wang, Huiyuan, Shin, Meong Cheol, Li, Feng, Yang, Victor C, Huang, Yongzhuo, 2018 Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites, Xu, Fan, Zhong, Huihai, Chang, Ya, Li, Dongdong, Jin, Hongyue, Zhang, Meng, Wang, Huiyuan, Jiang, Chen, Shen, Youqing, Huang, Yongzhuo, 2018 Dual-Targeting Biomimetic Delivery for Antiglioma via Remodeling Tumor Microenvironment and Directing Macrophage-Mediated Immunotherapy, Yongzhuo Huang, 2018 Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis, Kang, Xuejia, Zheng, Zenin, Liu, Zehua, Wang, Huiyuan, Zhao, Yuge, Zhang, Wenyuan, Shi, Mingjie, He, Yang, Cao, Yang, Xu, Qin, Peng, Chengyuan, Huang, Yongzhuo, 2018 Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation, Li, Dongdong, Zhang, Meng, Xu, Fan, Chen, Yingzhi, Chen, Binfan, Chang, Ya, Zhong, Huihai, Jin, Hongyue, Huang, Yongzhuo, 2018 Mannosylated Liposomal Codelivery of Dihydroartemisinin and Doxorubicin for Drug-Resistant Colon Cancer Therapy, Yongzhuo Huang, 2017 Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Li, Dongdong, Xu, Fan, Wu, Aihua, Wang, Jinyu, Huang, Yongzhuo, 2017 Microneedle-Assisted, DC-Targeted Codelivery of pTRP-2 and Adjuvant of Paclitaxel for Transcutaneous Immunotherapy, Xu, Jiaojiao, Xu, Beihua, Tao, Jin, Yang, Yunxu, Hu, Ying, Huang, Yongzhuo, 2017 Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat, Peng, Huige, Chen, Binfan, Huang, Wei, Tang, Yubo, Jiang, Yifan, Zhang, Wenyuan, Huang, Yongzhuo, 2017 Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy, Tan Jiao, Wang Huiyuan, Xu Fan, 2017 Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Tang, Yisi, Wu, Aihua, Huang, Yongzhuo, 2017 Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Tang, Yisi, Wang, Huiyuan, Xu, Qin, Li, Yaping, Li, Feng, Huang, Yongzhuo, 2017 Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy, Zhao, Pengfei, Yin, Weimin, Wu, Aihua, Tang, Yisi, Wang, Jinyu, Pan, Zhenzhen, Lin, Tingting, Zhang, Meng, Chen, Binfan, Duan, Yifei, Huang, Yongzhuo, 2017 Blood-Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy, Lin, Tingting, Zhao, Pengfei, Jiang, Yifan, Tang, Yisi, Jin, Hongyue, Pan, Zhenzhen, He, Huining, Yang, Victor C, Huang, Yongzhuo, 2016 Nuclear-targeting TAT-PEG-Asp8-Doxorubicin Polymeric Nanoassembly for Overcoming Drug-resistant Colon Cancer, Yongzhuo Huang, 2016 Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy, Cui, Yanna, Zhang, Meng, Zeng, Feng, Jin, Hongyue, Xu, Qin, Huang, Yongzhuo, 2016 Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization, Hu, Ying, Xu, Beihua, Xu, Jiaojiao, Shou, Dan, Liu, Ergang, Gao, Jianqing, Liang, Wenquan, Huang, Yongzhuo, 2015 A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging, Wang, Yaping, Lin, Tingting, Zhang, Wenyuan, Jiang, Yifan, Jin, Hongyue, He, Huining, Yang, Victor C, Chen, Yi, Huang, Yongzhuo, 2015 Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors, Wang, Huiyuan, Jiang, Yifan, Peng, Huige, Chen, Yingzhi, Zhu, Peizhi, Huang, Yongzhuo, 2015 Green synthesis of hyaluronic acid-based silver nanoparticles and their enhanced delivery to CD44(+) cancer cells, Liang, Jianming, Zeng, Feng, Zhang, Meng, Pan, Zhenzhen, Chen, Yingzhi, Zeng, Yuaner, Xu, Yong, Xu, Qin, Huang, Yongzhuo, 2015 Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer, Wang, Huixin, Zhao, Yongxing, Wang, Huiyuan, Gong, Junbo, He, Huining, Shin, Meong Cheol, Yang, Victor C, Huang, Yongzhuo, 2014 Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging, Jiang, Yifan, Lu, Junyan, Wang, Yaping, Zeng, Feng, Wang, Huiyuan, Peng, Huige, Huang, Min, Jiang, Hualiang, Luo, Cheng, Huang, Yongzhuo, 2014 Cell-Penetrating Peptide-Mediated Topical Delivery of Biomacromolecular Drugs, Tan, Jiao, Cheong, Heesun, Park, Yoon Shin, Kim, Hangun, Zhang, Meng, Moon, Cheol, Huang, Yongzhuo, 2014 CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery, Wang, Zhao, Chen, Yingzhi, Liu, Ergang, Gong, Junbo, Shin, Meong Cheol, Huang, Yongzhuo, 2014 Protease-Activatable Hybrid Nanoprobe for Tumor Imaging, Wang, Yaping, Jiang, Yifan, Zhang, Meng, Tan, Jiao, Liang, Jianming, Wang, Huixin, Li, Yaping, He, Huining, Yang, Victor C, Huang, Yongzhuo, 2014 Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer, Wang, Huiyuan, Li, Feng, Du, Chengan, Wang, Huixin, Mahato, Ram I, Huang, Yongzhuo, 2014 Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer, Wang, Huiyuan, Wang, Huixin, Liang, Jianming, Jiang, Yifan, Guo, Qianqian, Peng, Huige, Xu, Qin, Huang, Yongzhuo, 2014 Curb challenges of the 'Trojan Horse' approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery, Huang, Yongzhuo, Jiang, Yifan, Wang, Huiyuan, Wang, Jianxin, Shin, Meong Cheol, Byun, Youngro, He, Huining, Liang, Yanqin, Yang, Victor C, 2013 Cell-Penetrating Peptide-Modified PLGA Nanoparticles for Enhanced Nose-to-Brain Macromolecular Delivery, Yan, Lu, Wang, Huiyuan, Jiang, Yifan, Liu, Jinhua, Wang, Zhao, Yang, Yongxin, Huang, Shengwu, Huang, Yongzhuo, 2013 Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs, Wang, Ye, Liu, Ergang, Sun, Xiaoyi, Huang, Pengyu, Long, Hao, Wang, Hua, Yu, Xin, Zheng, Caihong, Huang, Yongzhuo, 2013 Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery, Sun, Yajuan, Dong, Weibing, Wang, Huiyuan, Huang, Yongzhuo, Gu, Huike, Yang, Victor C, Gong, Junbo, 2013 Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR(8) Peptide/p53 DNA for Cocktail Therapy, Wang, Huiyuan, Guo, Qianqian, Jiang, Yifan, Liu, Ergang, Zhao, Yongxing, Wang, Huixin, Li, Yaping, Huang, Yongzhuo, 2013 Cell-penetrating albumin conjugates

Areas of Focus

Transdermal New Formulations and Technologies
Biotechnology Drug Delivery Systems
Environmentally Responsive Tumor Molecular Probes and Imaging

Publications

Co-Delivery of Trichosanthin and Albendazole by Nano-Self-Assembly for Overcoming Tumor Multidrug-Resistance and Metastasis, Tang, Yisi, Liang, Jianming, Wu, Aihua, Chen, Yingzhi, Zhao, Pengfei, Lin, Tingting, Zhang, Meng, Xu, Qin, Wang, Jianxin, Huang, Yongzhuo, 2020
Improved Protein Toxin Delivery Based on ATTEMPTS Systems, Chen, Yingzhi, Zhang, Meng, Min, Kyoung Ah, Wang, Huiyuan, Shin, Meong Cheol, Li, Feng, Yang, Victor C, Huang, Yongzhuo, 2018
Targeting death receptors for drug-resistant cancer therapy: Codelivery of pTRAIL and monensin using dual-targeting and stimuli-responsive self-assembling nanocomposites, Xu, Fan, Zhong, Huihai, Chang, Ya, Li, Dongdong, Jin, Hongyue, Zhang, Meng, Wang, Huiyuan, Jiang, Chen, Shen, Youqing, Huang, Yongzhuo, 2018
Dual-Targeting Biomimetic Delivery for Antiglioma via Remodeling Tumor Microenvironment and Directing Macrophage-Mediated Immunotherapy, Yongzhuo Huang, 2018
Liposomal Codelivery of Doxorubicin and Andrographolide Inhibits Breast Cancer Growth and Metastasis, Kang, Xuejia, Zheng, Zenin, Liu, Zehua, Wang, Huiyuan, Zhao, Yuge, Zhang, Wenyuan, Shi, Mingjie, He, Yang, Cao, Yang, Xu, Qin, Peng, Chengyuan, Huang, Yongzhuo, 2018
Biomimetic albumin-modified gold nanorods for photothermo-chemotherapy and macrophage polarization modulation, Li, Dongdong, Zhang, Meng, Xu, Fan, Chen, Yingzhi, Chen, Binfan, Chang, Ya, Zhong, Huihai, Jin, Hongyue, Huang, Yongzhuo, 2018
Mannosylated Liposomal Codelivery of Dihydroartemisinin and Doxorubicin for Drug-Resistant Colon Cancer Therapy, Yongzhuo Huang, 2017
Glioma Dual-Targeting Nanohybrid Protein Toxin Constructed by Intein-Mediated Site-Specific Ligation for Multistage Booster Delivery, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Li, Dongdong, Xu, Fan, Wu, Aihua, Wang, Jinyu, Huang, Yongzhuo, 2017
Microneedle-Assisted, DC-Targeted Codelivery of pTRP-2 and Adjuvant of Paclitaxel for Transcutaneous Immunotherapy, Xu, Jiaojiao, Xu, Beihua, Tao, Jin, Yang, Yunxu, Hu, Ying, Huang, Yongzhuo, 2017
Reprogramming Tumor-Associated Macrophages To Reverse EGFR(T790M) Resistance by Dual-Targeting Codelivery of Gefitinib/Vorinostat, Peng, Huige, Chen, Binfan, Huang, Wei, Tang, Yubo, Jiang, Yifan, Zhang, Wenyuan, Huang, Yongzhuo, 2017
Poly-γ-glutamic acid-based GGT-targeting and surface camouflage strategy for improving cervical cancer gene therapy, Tan Jiao, Wang Huiyuan, Xu Fan, 2017
Prodrug-Like, PEGylated Protein Toxin Trichosanthin for Reversal of Chemoresistance, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Tang, Yisi, Wu, Aihua, Huang, Yongzhuo, 2017
Intein-mediated site-specific synthesis of tumor-targeting protein delivery system: Turning PEG dilemma into prodrug-like feature, Chen, Yingzhi, Zhang, Meng, Jin, Hongyue, Tang, Yisi, Wang, Huiyuan, Xu, Qin, Li, Yaping, Li, Feng, Huang, Yongzhuo, 2017
Dual-Targeting to Cancer Cells and M2 Macrophages via Biomimetic Delivery of Mannosylated Albumin Nanoparticles for Drug-Resistant Cancer Therapy, Zhao, Pengfei, Yin, Weimin, Wu, Aihua, Tang, Yisi, Wang, Jinyu, Pan, Zhenzhen, Lin, Tingting, Zhang, Meng, Chen, Binfan, Duan, Yifei, Huang, Yongzhuo, 2017
Blood-Brain-Barrier-Penetrating Albumin Nanoparticles for Biomimetic Drug Delivery via Albumin-Binding Protein Pathways for Antiglioma Therapy, Lin, Tingting, Zhao, Pengfei, Jiang, Yifan, Tang, Yisi, Jin, Hongyue, Pan, Zhenzhen, He, Huining, Yang, Victor C, Huang, Yongzhuo, 2016
Nuclear-targeting TAT-PEG-Asp8-Doxorubicin Polymeric Nanoassembly for Overcoming Drug-resistant Colon Cancer, Yongzhuo Huang, 2016
Dual-Targeting Magnetic PLGA Nanoparticles for Codelivery of Paclitaxel and Curcumin for Brain Tumor Therapy, Cui, Yanna, Zhang, Meng, Zeng, Feng, Jin, Hongyue, Xu, Qin, Huang, Yongzhuo, 2016
Microneedle-assisted dendritic cell-targeted nanoparticles for transcutaneous DNA immunization, Hu, Ying, Xu, Beihua, Xu, Jiaojiao, Shou, Dan, Liu, Ergang, Gao, Jianqing, Liang, Wenquan, Huang, Yongzhuo, 2015
A Prodrug-type, MMP-2-targeting Nanoprobe for Tumor Detection and Imaging, Wang, Yaping, Lin, Tingting, Zhang, Wenyuan, Jiang, Yifan, Jin, Hongyue, He, Huining, Yang, Victor C, Chen, Yi, Huang, Yongzhuo, 2015
Recent progress in microRNA delivery for cancer therapy by non-viral synthetic vectors, Wang, Huiyuan, Jiang, Yifan, Peng, Huige, Chen, Yingzhi, Zhu, Peizhi, Huang, Yongzhuo, 2015
Green synthesis of hyaluronic acid-based silver nanoparticles and their enhanced delivery to CD44(+) cancer cells, Liang, Jianming, Zeng, Feng, Zhang, Meng, Pan, Zhenzhen, Chen, Yingzhi, Zeng, Yuaner, Xu, Yong, Xu, Qin, Huang, Yongzhuo, 2015
Low-molecular-weight protamine-modified PLGA nanoparticles for overcoming drug-resistant breast cancer, Wang, Huixin, Zhao, Yongxing, Wang, Huiyuan, Gong, Junbo, He, Huining, Shin, Meong Cheol, Yang, Victor C, Huang, Yongzhuo, 2014
Molecular-Dynamics-Simulation-Driven Design of a Protease-Responsive Probe for In-Vivo Tumor Imaging, Jiang, Yifan, Lu, Junyan, Wang, Yaping, Zeng, Feng, Wang, Huiyuan, Peng, Huige, Huang, Min, Jiang, Hualiang, Luo, Cheng, Huang, Yongzhuo, 2014
Cell-Penetrating Peptide-Mediated Topical Delivery of Biomacromolecular Drugs, Tan, Jiao, Cheong, Heesun, Park, Yoon Shin, Kim, Hangun, Zhang, Meng, Moon, Cheol, Huang, Yongzhuo, 2014
CPP-mediated Protein Delivery in a Noncovalent Form: Proof-of-Concept for Percutaneous and Intranasal Delivery, Wang, Zhao, Chen, Yingzhi, Liu, Ergang, Gong, Junbo, Shin, Meong Cheol, Huang, Yongzhuo, 2014
Protease-Activatable Hybrid Nanoprobe for Tumor Imaging, Wang, Yaping, Jiang, Yifan, Zhang, Meng, Tan, Jiao, Liang, Jianming, Wang, Huixin, Li, Yaping, He, Huining, Yang, Victor C, Huang, Yongzhuo, 2014
Doxorubicin and Lapatinib Combination Nanomedicine for Treating Resistant Breast Cancer, Wang, Huiyuan, Li, Feng, Du, Chengan, Wang, Huixin, Mahato, Ram I, Huang, Yongzhuo, 2014
Cell-Penetrating Apoptotic Peptide/p53 DNA Nanocomplex as Adjuvant Therapy for Drug-Resistant Breast Cancer, Wang, Huiyuan, Wang, Huixin, Liang, Jianming, Jiang, Yifan, Guo, Qianqian, Peng, Huige, Xu, Qin, Huang, Yongzhuo, 2014
Curb challenges of the 'Trojan Horse' approach: Smart strategies in achieving effective yet safe cell-penetrating peptide-based drug delivery, Huang, Yongzhuo, Jiang, Yifan, Wang, Huiyuan, Wang, Jianxin, Shin, Meong Cheol, Byun, Youngro, He, Huining, Liang, Yanqin, Yang, Victor C, 2013
Cell-Penetrating Peptide-Modified PLGA Nanoparticles for Enhanced Nose-to-Brain Macromolecular Delivery, Yan, Lu, Wang, Huiyuan, Jiang, Yifan, Liu, Jinhua, Wang, Zhao, Yang, Yongxin, Huang, Shengwu, Huang, Yongzhuo, 2013
Pluronic L61 as a long-circulating modifier for enhanced liposomal delivery of cancer drugs, Wang, Ye, Liu, Ergang, Sun, Xiaoyi, Huang, Pengyu, Long, Hao, Wang, Hua, Yu, Xin, Zheng, Caihong, Huang, Yongzhuo, 2013
Template synthesis of PMAA@chitosan hollow nanorods for docetaxel delivery, Sun, Yajuan, Dong, Weibing, Wang, Huiyuan, Huang, Yongzhuo, Gu, Huike, Yang, Victor C, Gong, Junbo, 2013
Co-delivery of Cell-permeable Chimeric Apoptosis AVPIR(8) Peptide/p53 DNA for Cocktail Therapy, Wang, Huiyuan, Guo, Qianqian, Jiang, Yifan, Liu, Ergang, Zhao, Yongxing, Wang, Huixin, Li, Yaping, Huang, Yongzhuo, 2013
Cell-penetrating albumin conjugates

Transdermal New Formulations Technologies Chemical Drugs Traditional Chinese Medicine Transdermal Vaccine Delivery Biotechnology Drug Delivery Systems Nanotechnology Tumor Imaging

Mei Lijuan - University of Chinese Academy of Sciences

Yu-Bo Zhou - University of Chinese Academy of Sciences

Jinhui Wu - Nanjing University

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