Areas of Focus
- Somatic cell reprogramming and molecular mechanisms of stem cell aging
Work Experience
- 2021.12-Present: Tongji University, School of Life Sciences and Technology, Professor
- 2014.10-2021.12: Tongji University, School of Life Sciences and Technology, Assistant Professor
Academic Background & Achievements
- 2008-2014: PhD in Life Sciences, China Agricultural University, Beijing
- Recipient of the National Natural Science Foundation of China Outstanding Youth Science Fund (2021)
- Shanghai Science and Technology Committee Young Science and Technology Star (Class A) (2021)
- Shanghai Morning Light Plan recipient (2015)
Publications
- Dcaf11 activates Zscan4-mediated alternative telomere lengthening in early embryos and embryonic stem cells, Le Rongrong, 2020
- Enhanced telomere rejuvenation in pluripotent cells reprogrammed via nuclear transfer relative to induced pluripotent stem cells, Le Rongrong, 2014
- Unique Patterns of H3K4me3 and H3K27me3 in 2-Cell-like Embryonic Stem Cells, Le Rongrong, 2021
- Lessons from expanded potential of embryonic stem cells: Moving toward totipotency, Le Rongrong, 2020
- Oocyte-Specific Homeobox 1, Obox1, Facilitates Reprogramming by Promoting Mesenchymal-to-Epithelial Transition and Mitigating Cell Hyperproliferation, Le Rongrong, 2017
- Enhanced Rejuvenation in Induced Pluripotent Stem Cell Derived Neurons Compared with Directly Converted Neurons from an Aged Mouse, Le Rongrong, 2015
- High throughput sequencing identifies an imprinted gene, Grb10, associated with the pluripotency state in nuclear transfer embryonic stem cells, Le Rongrong, 2017
- Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs, Le Rongrong, 2017
- DCAF13 promotes pluripotency by negatively regulating SUV39H1 stability during early embryonic development, Le Rongrong, 2018
- Reduced Self-Diploidization and Improved Survival of Semi-cloned Mice Produced from Androgenetic Haploid Embryonic Stem Cells through Overexpression of Dnmt3b, Le Rongrong, 2018
- Reprogramming of H3K9me3-dependent heterochromatin during mammalian embryo development, Le Rongrong, 2018
