Professor | Maoxuan Liu | Asia Growth Partners

Name	Maoxuan Liu
Contact Information	mx.liu@siat.ac.cn
Language ability	Chinese, English
Province	Guangdong

Name

Maoxuan Liu

Contact Information

mx.liu@siat.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2014-09--2018-09 PhD: KU Leuven 2011-09--2014-06 Master's: Shandong University 2007-09--2011-06 Bachelor's: Shandong University
Work Experience	2023-01~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2020-09~2022-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher 2018-10~2020-09 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2014-09--2018-09 PhD: KU Leuven
2011-09--2014-06 Master's: Shandong University
2007-09--2011-06 Bachelor's: Shandong University

Work Experience

2023-01~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2020-09~2022-12 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Assistant Researcher
2018-10~2020-09 - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Postdoctoral Researcher

Areas of Focus	Gene-modified immune cell therapy technology Active substances and functions of natural medicines
Publications	NKG2D chimeric antigen receptor-expressing macrophages demonstrate cytotoxicity against tumor cells, Third Author, 2022 Comparative Study of the Efficacy of Two Mesothelin-targeting CAR-T Cells Against Triple Negative Breast Cancer, Second Author, 2022 CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro, First Author, 2022 Bioassay-Guided Isolation of Anthelmintic Components from Semen pharbitidis, and the Mechanism of Action of Pharbitin, Corresponding Author, 2022 GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay, Third Author, 2022 CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection, Fifth Author, 2021 Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical Evidence, Fourth Author, 2020 A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro, Ninth Author, 2020 Plant-Based Natural Products for the Discovery and Development of Novel Anthelmintics against Nematodes, First Author, 2020 Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms, Second Author, 2020 Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites, Corresponding Author, 2019 Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model, Corresponding Author, 2019 Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action, Corresponding Author, 2018 Active principles of Tetradenia riparia. IV. Anthelmintic activity of 8(14),15-sandaracopimaradiene-7 alpha,18-diol, Corresponding Author, 2018 Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial, Corresponding Author, 2018 Antimicrobial, Anthelmintic, and Antiviral Activity of Plants Traditionally Used for Treating Infectious Disease in the Similipal Biosphere Reserve, Odisha, India, Fourth Author, 2017 A novel pentapeptide originated from calf thymus named TIPP shows an inhibitory effect on lung allergic inflammation, Fifth Author, 2015 Hematopoietic effects and mechanisms of Fufang E'jiao Jiang on radiotherapy and chemotherapy-induced myelosuppressed mice, First Author, 2014 Therapeutic effects of Fufang E'jiao Jiang on renal anemia rats and its mechanisms, First Author, 2014 Effect of Colla corii asini (E'jiao) on D-Galactose Induced Aging Mice, Second Author, 2012

Areas of Focus

Gene-modified immune cell therapy technology
Active substances and functions of natural medicines

Publications

NKG2D chimeric antigen receptor-expressing macrophages demonstrate cytotoxicity against tumor cells, Third Author, 2022
Comparative Study of the Efficacy of Two Mesothelin-targeting CAR-T Cells Against Triple Negative Breast Cancer, Second Author, 2022
CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro, First Author, 2022
Bioassay-Guided Isolation of Anthelmintic Components from Semen pharbitidis, and the Mechanism of Action of Pharbitin, Corresponding Author, 2022
GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay, Third Author, 2022
CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection, Fifth Author, 2021
Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical Evidence, Fourth Author, 2020
A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro, Ninth Author, 2020
Plant-Based Natural Products for the Discovery and Development of Novel Anthelmintics against Nematodes, First Author, 2020
Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms, Second Author, 2020
Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites, Corresponding Author, 2019
Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model, Corresponding Author, 2019
Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action, Corresponding Author, 2018
Active principles of Tetradenia riparia. IV. Anthelmintic activity of 8(14),15-sandaracopimaradiene-7 alpha,18-diol, Corresponding Author, 2018
Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial, Corresponding Author, 2018
Antimicrobial, Anthelmintic, and Antiviral Activity of Plants Traditionally Used for Treating Infectious Disease in the Similipal Biosphere Reserve, Odisha, India, Fourth Author, 2017
A novel pentapeptide originated from calf thymus named TIPP shows an inhibitory effect on lung allergic inflammation, Fifth Author, 2015
Hematopoietic effects and mechanisms of Fufang E'jiao Jiang on radiotherapy and chemotherapy-induced myelosuppressed mice, First Author, 2014
Therapeutic effects of Fufang E'jiao Jiang on renal anemia rats and its mechanisms, First Author, 2014
Effect of Colla corii asini (E'jiao) on D-Galactose Induced Aging Mice, Second Author, 2012

Gene Therapy Immune Cells Car-T Cells Natural Medicines Active Substances Function Biotechnology Cancer Treatment Immunotherapy Pharmacology

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