Professor | 刘茂玄 | 数字化转型顾问

Name	刘茂玄
Contact Information	mx.liu@siat.ac.cn
Language ability	中文, 英语
Province	广东

Name

刘茂玄

Contact Information

mx.liu@siat.ac.cn

Language ability

中文, 英语

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Medical School
Academic Background & Achievements	2014-09--2018-09 博士: 鲁汶大学 2011-09--2014-06 硕士: 山东大学 2007-09--2011-06 学士: 山东大学
Work Experience	2023-01~现在 - 中国科学院深圳先进技术研究院 - 副研究员 2020-09~2022-12 - 中国科学院深圳先进技术研究院 - 助理研究员 2018-10~2020-09 - 中国科学院深圳先进技术研究院 - 博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Medical School

Academic Background & Achievements

2014-09--2018-09 博士: 鲁汶大学
2011-09--2014-06 硕士: 山东大学
2007-09--2011-06 学士: 山东大学

Work Experience

2023-01~现在 - 中国科学院深圳先进技术研究院 - 副研究员
2020-09~2022-12 - 中国科学院深圳先进技术研究院 - 助理研究员
2018-10~2020-09 - 中国科学院深圳先进技术研究院 - 博士后

Areas of Focus	基因修饰免疫细胞治疗技术天然药物活性物质与功能
Publications	靶向NKG2D配体的嵌合抗原受体巨噬细胞具有肿瘤杀伤功能, 第三作者, 2022 两种靶向间皮素的CAR-T细胞杀伤三阴乳腺癌效果的对比研究, 第二作者, 2022 CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro, 第一作者, 2022 Bioassay-Guided Isolation of Anthelmintic Components from Semen pharbitidis, and the Mechanism of Action of Pharbitin, 通讯作者, 2022 GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay, 第三作者, 2022 CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection, 第五作者, 2021 Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical Evidence, 第四作者, 2020 A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro, 第九作者, 2020 Plant-Based Natural Products for the Discovery and Development of Novel Anthelmintics against Nematodes, 第一作者, 2020 Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms, 第二作者, 2020 Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites, 通讯作者, 2019 Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model, 通讯作者, 2019 Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action, 通讯作者, 2018 Active principles of Tetradenia riparia. IV. Anthelmintic activity of 8(14),15-sandaracopimaradiene-7 alpha,18-diol, 通讯作者, 2018 Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial, 通讯作者, 2018 Antimicrobial, Anthelmintic, and Antiviral Activity of Plants Traditionally Used for Treating Infectious Disease in the Similipal Biosphere Reserve, Odisha, India, 第四作者, 2017 A novel pentapeptide originated from calf thymus named TIPP shows an inhibitory effect on lung allergic inflammation, 第五作者, 2015 Hematopoietic effects and mechanisms of Fufang E'jiao Jiang on radiotherapy and chemotherapy-induced myelosuppressed mice, 第一作者, 2014 复方阿胶浆对肾性贫血大鼠的治疗作用及其机制, 第一作者, 2014 Effect of Colla corii asini (E'jiao) on D-Galactose Induced Aging Mice, 第二作者, 2012

Areas of Focus

基因修饰免疫细胞治疗技术
天然药物活性物质与功能

Publications

靶向NKG2D配体的嵌合抗原受体巨噬细胞具有肿瘤杀伤功能, 第三作者, 2022
两种靶向间皮素的CAR-T细胞杀伤三阴乳腺癌效果的对比研究, 第二作者, 2022
CAR-Macrophages and CAR-T Cells Synergistically Kill Tumor Cells In Vitro, 第一作者, 2022
Bioassay-Guided Isolation of Anthelmintic Components from Semen pharbitidis, and the Mechanism of Action of Pharbitin, 通讯作者, 2022
GPC3-targeted CAR-T cells secreting B7H3-targeted BiTE exhibit potent cytotoxicity activity against hepatocellular carcinoma cell in the in vitro assay, 第三作者, 2022
CD317 mediates immunocytolysis resistance by RICH2/cytoskeleton-dependent membrane protection, 第五作者, 2021
Antibacterial, Antifungal, Antiviral, and Anthelmintic Activities of Medicinal Plants of Nepal Selected Based on Ethnobotanical Evidence, 第四作者, 2020
A novel virtual screening procedure identifies Pralatrexate as inhibitor of SARS-CoV-2 RdRp and it reduces viral replication in vitro, 第九作者, 2020
Plant-Based Natural Products for the Discovery and Development of Novel Anthelmintics against Nematodes, 第一作者, 2020
Biofilm inhibiting properties of compounds from the leaves of Warburgia ugandensis Sprague subsp ugandensis against Candida and staphylococcal biofilms, 第二作者, 2020
Screening of a drug repurposing library with a nematode motility assay identifies promising anthelmintic hits against Cooperia oncophora and other ruminant parasites, 通讯作者, 2019
Bioassay-guided isolation of anti-seizure principles from Semen Pharbitidis using a zebrafish pentylenetetrazol seizure model, 通讯作者, 2019
Bioassay-guided isolation of active substances from Semen Torreyae identifies two new anthelmintic compounds with novel mechanism of action, 通讯作者, 2018
Active principles of Tetradenia riparia. IV. Anthelmintic activity of 8(14),15-sandaracopimaradiene-7 alpha,18-diol, 通讯作者, 2018
Bioassay-guided isolation of three anthelmintic compounds from Warburgia ugandensis Sprague subspecies ugandensis, and the mechanism of action of polygodial, 通讯作者, 2018
Antimicrobial, Anthelmintic, and Antiviral Activity of Plants Traditionally Used for Treating Infectious Disease in the Similipal Biosphere Reserve, Odisha, India, 第四作者, 2017
A novel pentapeptide originated from calf thymus named TIPP shows an inhibitory effect on lung allergic inflammation, 第五作者, 2015
Hematopoietic effects and mechanisms of Fufang E'jiao Jiang on radiotherapy and chemotherapy-induced myelosuppressed mice, 第一作者, 2014
复方阿胶浆对肾性贫血大鼠的治疗作用及其机制, 第一作者, 2014
Effect of Colla corii asini (E'jiao) on D-Galactose Induced Aging Mice, 第二作者, 2012

基因治疗免疫细胞 Car-T细胞天然药物活性物质功能生物技术癌症治疗免疫治疗药理学

许扬 - 南方科技大学

姜鹏 - 武汉大学

孙华文 - 武汉大学

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