2008-09 - Ph.D.: Chengdu Institute of Biology, Chinese Academy of Sciences
2005-09 - Bachelor's: Sichuan Agricultural University
2005-09 - Master's: Shenyang Institute of Applied Ecology, Chinese Academy of Sciences
2013-09 to present - Chengdu Institute of Biology, Chinese Academy of Sciences - Associate Researcher
2011-08 to present - Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences - Postdoctoral Researcher
Research
Bio-inspired organic synthesis methodology Asymmetric catalysis of small organic molecules Structural modification of active natural products Drug synthesis process research
The Journal of Organic Chemistry, Guangxun Li, 2023
ACS Catalysis, Guangxun Li, 2023
Organic Letters, Guangxun Li, 2023
Chinese Chemical Letters, Guangxun Li, 2023
Chiral Phosphoric Acid Catalyzed Enantioselective Desymmetrization of 1,4-Dihydropyridines by C(sp3 ), Min Han, Shi-qi Zhang, Xin Cui, Qi-wei Wang, Guang-xun Li, zhuo tang, 2022
Chiral Primary Amine Catalyzed Enantioselective Tandem Reactions Based on Heyns Rearrangement: Synthesis of α-Tertiary Amino Ketones, Xiao-kang Nie, Yue Chen, Shi-qi Zhang, Xin Cui, Zhuo Tang, Guang-xun Li, 2022
A heterobifunctional molecule recruits cereblon to an RNA scaffold and activates its PROTAC function, Xu, Yan, Fu, Dingqiang, Yuan, Yi, Peng, Yan, Dong, Juan, Du, Feng, Huang, Xin, Li, Guangxun, Chen, Xiaohua, Wang, Qiwei, Tang, Zhuo, 2022
Photoredox Alkylation of Sulfinylamine Enables the Synthesis of Highly Functionalized Sulfinamides and S(VI) Derivatives, Li, Ling, Zhang, Shiqi, Chen, Yue, Cui, Xin, Zhao, Gang, Tang, Zhuo, Li, Guangxun, 2022
Preparation of Dihydronaphthofurans from α-Hydroxyl Ketones via a One-Pot Multicomponent Reaction Based on Heyns Rearrangement, Jin Huang, Jin-fang Chen, Xin Cui, Jin-zhong Zhao, Zhuo Tang, Guang-xun Li, 2022
Tetrahedron Lett., Guangxun Li, 2022
New J. Chem., Guangxun Li, 2022
Regioselective, Diastereoselective, and Enantioselective One-Pot Tandem Reaction Based on an in Situ Formed Reductant: Preparation of 2,3-Disubstituted 1,5-Benzodiazepine, Yang, Gaofeng, Li, Guangxun, Huang, Jin, Fu, Dingqiang, Nie, Xiaokang, Cui, Xin, Zhao, Jinzhong, Tang, Zhuo, 2021
Catalytic asymmetric synthesis of N-substituted tetrahydroquinoxalines via regioselective Heyns rearrangement and stereoselective transfer hydrogenation in one pot, Huang, Jin, Li, Guangxun, Yang, Gaofeng, Fu, Dingqiang, Nie, Xiaokang, Cui, Xin, Zhao, Jinzhong, Tang, Zhuo, 2021
An organocatalytic asymmetric Friedel–Crafts reaction of 2-substituted indoles with aldehydes: enantioselective synthesis of a-hydroxyl ketones by low loading of chiral phosphoric acid, Deng, Xiongfei, Tang, Zhuo, 2020
Pictet-Spengler reaction based onin situgenerated alpha-amino iminium ions through the Heyns rearrangement, Liang, Junxiu, Yang, Guobin, Zhang, Yongpo, Guo, Dongdong, Zhao, Jinzhong, Li, Guangxun, Tang, Zhuo, 2020
Chiral Bronsted-Acid-Catalyzed Asymmetric Oxidation of Sulfenamide by Using H2O2: A Versatile Access to Sulfinamide and Sulfoxide with High Enantioselectivity, Ma, Longjun, Chen, Shusen, Li, Guangxun, Zhu, Jin, Wang, Qiwei, Tang, Zhuo, 2019
Preparation of Bicyclic Ketal Skeletons with Aldehyde and alpha-Ketone Acid through Cascade Friedel-Crafts Reaction and Stereoselective Acetalization in One Pot, Li, Ling, Wang, Yingwei, Zhang, Shiqi, Dong, Xiongfei, Li, Guangxun, Zhao, Gang, Tang, Zhuo, 2019
Chiral Brønsted-Acid-Catalyzed Asymmetric Oxidation of Sulfenamide by Using H2O2: A Versatile Access to Sulfinamide and Sulfoxide with High Enantioselectivity, Guangxun Li, 2019
Solvent-Free Synthesis of -Amino Ketones from -Hydroxyl Ketones via A Novel Tandem Reaction Sequence Based on Heyns Rearrangement, Li, Lingyu, Zeng, Qingle, Li, Guangxun, Tang, Zhuo, 2019
Bioinspired Catalysis: Self-Assembly of a Protein and DNA as a Catalyst for the Aldol Reaction in Aqueous Media, Liu, Hongxin, Li, Guangxun, Wang, Yingwei, Zhang, Shiqi, Tang, Zhuo, 2018
Synthesis of asymmetrical thioethers with sulfinamides as the sulfenylation agent under metal-free conditions, Ma, Longjun, Li, Guangxun, Huang, Jin, Zhu, Jin, Tang, Zhuo, 2018
Using sulfinamides as high oxidation state sulfur reagent for preparation of sulfenamides, Ma, Longjun, Li, Guangxun, Huang, Jin, Zhu, Jin, Tang, Zhuo, 2018
Brønsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel–Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines, Zhuo Tang, 2017
BrOnsted-Acid-Catalyzed Substrate-Controlled and Site-Selective Friedel-Crafts Alkylation: A New Strategy for Post-Modification of 1,2-Dihydroquinolines, Huang, Jin, Li, Guangxun, Yang, Guobin, Zhao, Jinzhong, Tang, Zhuo, 2017
Step-Controlled Povarov-Type Reaction with 1,2-Dihydroquinolines as Precursors of Dienophiles: Direct Synthesis of Spirocyclic Bi-tetrahydroquinolines and Functionalized 1,2-Dihydroquinolines, Ren, Xuwen, Li, Guangxun, Huang, Jin, Wang, Weidong, Zhang, Yongpo, Xing, Guomin, Gao, Chunyan, Zhao, Gang, Zhao, Jinzhong, Tang, Zhuo, 2017
Bio-inspired enantioselective full transamination using readily available cyclodextrin, Zhang, Shiqi, Li, Guangxun, Liu, Hongxin, Wang, Yingwei, Cao, Yuan, Zhao, Gang, Tang, Zhuo, 2017
A one pot three-component reaction for the preparation of dihydroquinolines with two different ketones and aromatic amines, Yang, Guobin, Li, Guangxun, Huang, Jin, Tang, Zhuo, Zhao, Jinzhong, 2017
The catalytic enantioselective synthesis of tetrahydroquinolines containing all-carbon quaternary stereocenters via the formation of aza-ortho-xylylene with 1,2-dihydroquinoline as a precursor, Li, Guangxun, Liu, Hongxin, Wang, Yingwei, Zhang, Shiqi, Lai, Shujun, Tang, Ling, Zhao, Jinzhong, Tang, Zhuo, 2016
Investigation and Application of Amphoteric alpha-Amino Aldehyde: An in Situ Generated Species Based on Heyns Rearrangement, Li, Guangxun, Tang, Ling, Liu, Hongxin, Wang, Yingwei, Zhao, Gang, Tang, Zhuo, 2016
The catalytic enantioselective synthesis of tetrahydroquinolines containing all-carbon quaternary stereocenters via the formation of aza-ortho-xylylene with 1,2-dihydroquinoline as a precursor., Li Guangxun, Liu Hongxin, Wang Yingwei, Zhang Shiqi, Lai Shujun, Tang Ling, Zhao Jinzhong, Tang Zhuo, 2016
Simple Brønsted acid catalyzed C–H functionalization: efficient access to poly-substituted pyridines, Lai Shujun, Ren Xuwen, Zhao Jinzhong, Tang Zhuo, Li Guangxun, 2016
Area of Focus
Chemical | Pharmacy | Research | Education | Healthcare | Drug Synthesis | Pharmacology | Biotechnology | Organic Chemistry | Medicinal Chemistry
