Professor | Chune Dong | Asia Growth Partners

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Name	Chune Dong
Language ability	Chinese, English
Province	Hubei

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Name

Chune Dong

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2000 - PhD in Organic Chemistry, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences Postdoctoral Researcher at University of Vienna, University of Ottawa, and University of Illinois at Urbana-Champaign
Work Experience	2000-2001 - University of Vienna, Postdoctoral Researcher 2002-2004 - University of Ottawa, Postdoctoral Researcher 2004-2006 - University of Illinois at Urbana-Champaign, Postdoctoral Researcher

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2000 - PhD in Organic Chemistry, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences
Postdoctoral Researcher at University of Vienna, University of Ottawa, and University of Illinois at Urbana-Champaign

Work Experience

2000-2001 - University of Vienna, Postdoctoral Researcher
2002-2004 - University of Ottawa, Postdoctoral Researcher
2004-2006 - University of Illinois at Urbana-Champaign, Postdoctoral Researcher

Areas of Focus	Synthesis of small molecules with potential medicinal activity Research on new methods in organic chemistry, especially carbon-heteroatom bonding and asymmetric catalysis Design and synthesis of biomimetic ion channels and study of their activity
Publications	An Expedient Approach to Highly Enantioenriched Cyclic Nitrones Mediated by Robust and Recoverable C3-Symmetric Cinchonine-Squaramide Catalyst, Chune Dong, 2012 A New Pathway for Phthalazine Derivatives via Metal-free Cyclization of ortho-Alkynylphenyl ketones and Hydrazine, Chune Dong, 2013 A simple and straightforward approach toward selective C=C bond reduction by hydrazine, Chune Dong, 2012 Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indole with alkyl trifluoro pyruvate, Chune Dong, 2012 Chiral Squaramide as Multiple H-Bonds Donor Organocatalyst for Asymmetric Michael addition of 1, 3-Dicarbonyl Compounds to Nitroolefins, Chune Dong, 2012 Identification and structure-Activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2,2,1]hept-2-ene-7-oxide, Chune Dong, 2012 C3-symmetric cinchonine-squaramide as new highly efficient and recyclable organocatalyst for enantioselective michael addition, Chune Dong, 2011 A Novel C3-Symmetric Prolinol-Squaramide Catalyst for the Asymmetric Reduction of Ketones by Borane, Chune Dong, 2011 Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono diketones to nitroalkenes, Chune Dong, 2011 Facile synthesis of 1,3,4-benzotriazepines and 1-arylamide-1H-indazoles via palladium catalyzed cyclization of aryl isocyanates and aryl hydrazones under microwave irradiation, Chune Dong, 2010 Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo [2.2.1]hepte-ne scaffold and evaluation of their antiproliferative effects, Chune Dong, 2012 Biocyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfon-amides, Chune Dong, 2012 Development of selective estrogen receptor modulator SERM-like activity through an indirect mechanism of estrogen receptor antagonism defining the binding mode of 7-oxabicyclo[2.2.1] hept-5-ene scaffold core ligands, Chune Dong, 2012 Progress in small molecular inhibitors of protein protein interactions, Chune Dong, 2010

Areas of Focus

Synthesis of small molecules with potential medicinal activity
Research on new methods in organic chemistry, especially carbon-heteroatom bonding and asymmetric catalysis
Design and synthesis of biomimetic ion channels and study of their activity

Publications

An Expedient Approach to Highly Enantioenriched Cyclic Nitrones Mediated by Robust and Recoverable C3-Symmetric Cinchonine-Squaramide Catalyst, Chune Dong*, 2012
A New Pathway for Phthalazine Derivatives via Metal-free Cyclization of ortho-Alkynylphenyl ketones and Hydrazine, Chune Dong*, 2013
A simple and straightforward approach toward selective C=C bond reduction by hydrazine, Chune Dong*, 2012
Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indole with alkyl trifluoro pyruvate, Chune Dong*, 2012
Chiral Squaramide as Multiple H-Bonds Donor Organocatalyst for Asymmetric Michael addition of 1, 3-Dicarbonyl Compounds to Nitroolefins, Chune Dong*, 2012
Identification and structure-Activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2,2,1]hept-2-ene-7-oxide, Chune Dong, 2012
C3-symmetric cinchonine-squaramide as new highly efficient and recyclable organocatalyst for enantioselective michael addition, Chune Dong*, 2011
A Novel C3-Symmetric Prolinol-Squaramide Catalyst for the Asymmetric Reduction of Ketones by Borane, Chune Dong*, 2011
Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono diketones to nitroalkenes, Chune Dong*, 2011
Facile synthesis of 1,3,4-benzotriazepines and 1-arylamide-1H-indazoles via palladium catalyzed cyclization of aryl isocyanates and aryl hydrazones under microwave irradiation, Chune Dong*, 2010
Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo [2.2.1]hepte-ne scaffold and evaluation of their antiproliferative effects, Chune Dong, 2012
Biocyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfon-amides, Chune Dong, 2012
Development of selective estrogen receptor modulator SERM-like activity through an indirect mechanism of estrogen receptor antagonism defining the binding mode of 7-oxabicyclo[2.2.1] hept-5-ene scaffold core ligands, Chune Dong, 2012
Progress in small molecular inhibitors of protein protein interactions, Chune Dong*, 2010

Medicinal Chemistry Synthesis Organic Chemistry Carbon-Heteroatom Bonding Asymmetric Catalysis Biomimetics Ion Channels Chemical Synthesis Research Pharmaceuticals

Jian Liao - University of Chinese Academy of Sciences

Guangxun Li - University of Chinese Academy of Sciences

Jian Yu - Wuhan University

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