Professor | 董春娥 | 数字化转型顾问

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Name	董春娥
Language ability	中文, 英语
Province	湖北省

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Name

董春娥

Language ability

中文, 英语

Province

湖北省

University/Lab Affiliation and Title	武汉大学
Faculty	Medical School
Academic Background & Achievements	2000年 - 有机化学博士，中国科学院成都有机化学研究所在维也纳大学、渥太华大学和伊利诺伊大学香槟分校做博士后研究
Work Experience	2000-2001 - 维也纳大学，博士后研究员 2002-2004 - 渥太华大学，博士后研究员 2004-2006 - 伊利诺伊大学香槟分校，博士后研究员

University/Lab Affiliation and Title

武汉大学

Faculty

Medical School

Academic Background & Achievements

2000年 - 有机化学博士，中国科学院成都有机化学研究所
在维也纳大学、渥太华大学和伊利诺伊大学香槟分校做博士后研究

Work Experience

2000-2001 - 维也纳大学，博士后研究员
2002-2004 - 渥太华大学，博士后研究员
2004-2006 - 伊利诺伊大学香槟分校，博士后研究员

Areas of Focus	具有潜在药物活性小分子的新法合成研究有机化学新方法研究，特别是碳-杂键的构键以及不对称催化研究生物模拟离子通道的设计合成和活性研究
Publications	An Expedient Approach to Highly Enantioenriched Cyclic Nitrones Mediated by Robust and Recoverable C3-Symmetric Cinchonine-Squaramide Catalyst, 董春娥, 2012 A New Pathway for Phthalazine Derivatives via Metal-free Cyclization of ortho-Alkynylphenyl ketones and Hydrazine, 董春娥, 2013 A simple and straightforward approach toward selective C=C bond reduction by hydrazine, 董春娥, 2012 Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indole with alkyl trifluoro pyruvate, 董春娥, 2012 Chiral Squaramide as Multiple H-Bonds Donor Organocatalyst for Asymmetric Michael addition of 1, 3-Dicarbonyl Compounds to Nitroolefins, 董春娥, 2012 Identification and structure-Activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2,2,1]hept-2-ene-7-oxide, 董春娥, 2012 C3-symmetric cinchonine-squaramide as new highly efficient and recyclable organocatalyst for enantioselective michael addition, 董春娥, 2011 A Novel C3-Symmetric Prolinol-Squaramide Catalyst for the Asymmetric Reduction of Ketones by Borane, 董春娥, 2011 Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono diketones to nitroalkenes, 董春娥, 2011 Facile synthesis of 1,3,4-benzotriazepines and 1-arylamide-1H-indazoles via palladium catalyzed cyclization of aryl isocyanates and aryl hydrazones under microwave irradiation, 董春娥, 2010 Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo [2.2.1]hepte-ne scaffold and evaluation of their antiproliferative effects, 董春娥, 2012 Biocyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfon-amides, 董春娥, 2012 Development of selective estrogen receptor modulator SERM-like activity through an indirect mechanism of estrogen receptor antagonism defining the binding mode of 7-oxabicyclo[2.2.1] hept-5-ene scaffold core ligands, 董春娥, 2012 Progress in small molecular inhibitors of protein protein interactions, 董春娥, 2010

Areas of Focus

具有潜在药物活性小分子的新法合成研究
有机化学新方法研究，特别是碳-杂键的构键以及不对称催化研究
生物模拟离子通道的设计合成和活性研究

Publications

An Expedient Approach to Highly Enantioenriched Cyclic Nitrones Mediated by Robust and Recoverable C3-Symmetric Cinchonine-Squaramide Catalyst, 董春娥*, 2012
A New Pathway for Phthalazine Derivatives via Metal-free Cyclization of ortho-Alkynylphenyl ketones and Hydrazine, 董春娥*, 2013
A simple and straightforward approach toward selective C=C bond reduction by hydrazine, 董春娥*, 2012
Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indole with alkyl trifluoro pyruvate, 董春娥*, 2012
Chiral Squaramide as Multiple H-Bonds Donor Organocatalyst for Asymmetric Michael addition of 1, 3-Dicarbonyl Compounds to Nitroolefins, 董春娥*, 2012
Identification and structure-Activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2,2,1]hept-2-ene-7-oxide, 董春娥, 2012
C3-symmetric cinchonine-squaramide as new highly efficient and recyclable organocatalyst for enantioselective michael addition, 董春娥*, 2011
A Novel C3-Symmetric Prolinol-Squaramide Catalyst for the Asymmetric Reduction of Ketones by Borane, 董春娥*, 2011
Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono diketones to nitroalkenes, 董春娥*, 2011
Facile synthesis of 1,3,4-benzotriazepines and 1-arylamide-1H-indazoles via palladium catalyzed cyclization of aryl isocyanates and aryl hydrazones under microwave irradiation, 董春娥*, 2010
Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo [2.2.1]hepte-ne scaffold and evaluation of their antiproliferative effects, 董春娥, 2012
Biocyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfon-amides, 董春娥, 2012
Development of selective estrogen receptor modulator SERM-like activity through an indirect mechanism of estrogen receptor antagonism defining the binding mode of 7-oxabicyclo[2.2.1] hept-5-ene scaffold core ligands, 董春娥, 2012
Progress in small molecular inhibitors of protein protein interactions, 董春娥*, 2010

药物化学合成有机化学碳-杂键不对称催化仿生学离子通道化学合成研究药品

廖建 - 中国科学院大学

李光勋 - 中国科学院大学

喻健 - 武汉大学

Area of Focus
儿科 | 口腔健康 | 疾病治疗 | 诊断 | 生物材料 | 矿化 | 硬组织 | 仿生学 | 研究 | 临床应用

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