Upload Avatar (500 x 500)
董春娥
Medical School
武汉大学
湖北省
Language: 中文, 英语
药物化学
合成
有机化学
碳-杂键
不对称催化
仿生学
离子通道
化学合成
研究
药品
Areas of Focus
- 具有潜在药物活性小分子的新法合成研究
- 有机化学新方法研究，特别是碳-杂键的构键以及不对称催化研究
- 生物模拟离子通道的设计合成和活性研究
Work Experience
- 2000-2001 - 维也纳大学，博士后研究员
- 2002-2004 - 渥太华大学，博士后研究员
- 2004-2006 - 伊利诺伊大学香槟分校，博士后研究员
Academic Background & Achievements
- 2000年 - 有机化学博士，中国科学院成都有机化学研究所
- 在维也纳大学、渥太华大学和伊利诺伊大学香槟分校做博士后研究
Publications
- An Expedient Approach to Highly Enantioenriched Cyclic Nitrones Mediated by Robust and Recoverable C3-Symmetric Cinchonine-Squaramide Catalyst, 董春娥*, 2012
- A New Pathway for Phthalazine Derivatives via Metal-free Cyclization of ortho-Alkynylphenyl ketones and Hydrazine, 董春娥*, 2013
- A simple and straightforward approach toward selective C=C bond reduction by hydrazine, 董春娥*, 2012
- Enhanced efficiency of recyclable C3-symmetric cinchonine-squaramides in the asymmetric Friedel-Crafts reaction of indole with alkyl trifluoro pyruvate, 董春娥*, 2012
- Chiral Squaramide as Multiple H-Bonds Donor Organocatalyst for Asymmetric Michael addition of 1, 3-Dicarbonyl Compounds to Nitroolefins, 董春娥*, 2012
- Identification and structure-Activity relationships of a novel series of estrogen receptor ligands based on 7-thiabicyclo[2,2,1]hept-2-ene-7-oxide, 董春娥, 2012
- C3-symmetric cinchonine-squaramide as new highly efficient and recyclable organocatalyst for enantioselective michael addition, 董春娥*, 2011
- A Novel C3-Symmetric Prolinol-Squaramide Catalyst for the Asymmetric Reduction of Ketones by Borane, 董春娥*, 2011
- Novel bifunctional chiral squaramide-amine catalysts for highly enantioselective addition of mono diketones to nitroalkenes, 董春娥*, 2011
- Facile synthesis of 1,3,4-benzotriazepines and 1-arylamide-1H-indazoles via palladium catalyzed cyclization of aryl isocyanates and aryl hydrazones under microwave irradiation, 董春娥*, 2010
- Discovery of novel SERMs with a ferrocenyl entity based on the oxabicyclo [2.2.1]hepte-ne scaffold and evaluation of their antiproliferative effects, 董春娥, 2012
- Biocyclic core estrogens as full antagonists: synthesis, biological evaluation and structure-activity relationships of estrogen receptor ligands based on bridged oxabicyclic core arylsulfon-amides, 董春娥, 2012
- Development of selective estrogen receptor modulator SERM-like activity through an indirect mechanism of estrogen receptor antagonism defining the binding mode of 7-oxabicyclo[2.2.1] hept-5-ene scaffold core ligands, 董春娥, 2012
- Progress in small molecular inhibitors of protein protein interactions, 董春娥*, 2010
