Areas of Focus
- Marine Natural Product Chemistry
- Medicinal Chemistry
Work Experience
- 2015-10 to Present - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Associate Researcher
- 2015-05 to 2015-09 - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Assistant Researcher
- 2014-05 to 2015-04 - Swiss Federal Institute of Technology Zurich - Postdoctoral Researcher
- 2013-12 to 2014-05 - French National Center for Scientific Research - Research Assistant
Academic Background & Achievements
- 2010-09 to 2013-12 PhD: Université Pierre et Marie Curie (Paris VI)
- 2007-09 to 2010-07 Master's: East China Normal University
- 2003-09 to 2007-07 Bachelor's: Tianjin University
Publications
- Yonarolide A, an unprecedented furanobutenolide-containing norcembranoid derivative formed by photoinduced intramolecular 2+2 cycloaddition, Du, Yeqing, Yao, Ligong, Li, Xuwen, Guo, Yuewei, 2023
- Bioactivity-driven synthesis of the marine natural product naamidine J and its derivatives as potential tumor immunological agents by inhibiting programmed death-ligand 1, Fu Panpan, Wang qun, Zhang Qing, Jin Yang, Liu Jin, Chen Kaixian, Guo Yuewei, Liu sanhong, Li Xuwen, 2023
- Function-oriented synthesis of Imidazo1,2-apyrazine and Imidazo1,2-b pyridazine derivatives as potent PI3K/mTOR dual inhibitors, Li, Chuchu, Han, Yuqiao, Wang, Zhengyang, Yu, Yanan, Wang, Chen, Ren, Ziwei, Guo, Yanzhi, Zhu, Tong, Li, XuWen, Dong, Suzhen, Ma, Mingliang, 2023
- Recent advances on marine mollusk-derived natural products: chemistry, chemical ecology and therapeutical potential, Chen, ZiHui, Guo, YueWei, Li, XuWen, 2023
- Chemistry, Chemo-Ecology, and Biological Activities of Uncommon and Structurally Diverse Sesquiterpenoids from the Sanya Bay Nudibranch Hexabranchus sanguineus, Shou-Mao Shen, Ming-Zhi Su, Dan-Dan Yu, Hui Luo, Xu-Wen LI, Yue-Wei Guo, 2023
- Extending the record of dolabellane-type diterpenoids from the soft coral Clavularia viridis: Structures and stereochemistry, YeQing Du, Yuan Gao, Yi Zang, Jia Li, XuWen Li, YueWei Guo, 2023
- Ocellatuperoxides A–F, Uncommon Anti-Tumoral γ -Pyrone Peroxides from a Photosynthetic Mollusk Placobranchus ocellatus, SongWei Li, Qihao Wu, Heng Xu, LiGong Yao, Cheng Luo, Hong Wang, Hao Zhang, XuWen Li, YueWei Guo, 2022
- New diterpenoids from the South China Sea soft coral Sinularia pedunculata, Fu, PanPan, Jin, Yang, Yao, LiGong, Guo, YueWei, Li, XuWen, 2022
- Natural Product-Inspired Targeted Protein Degraders: Advances and Perspectives, Li, Jiao, Cai, Zhenyu, Li, XuWen, Zhuang, Chunlin, 2022
- Ximaoornatins A–C, Polyoxygenated Diterpenoids from the Hainan Soft Coral Sinularia ornata, LiLi Sun, XuWen Li, YueWei Guo, 2022
- Design, synthesis and in vitro biological evaluation of marine phidianidine derivatives as potential anti-inflammatory agents, Quan Xu, Ning Zhao, Jin Liu, JinQian Song, LiHua Huang, Hong Wang, XuWen Li, Tao Pang, YueWei Guo, 2022
- New Cladiellin-Type Diterpenoids from the South China Sea Soft Coral Cladiella krempfi : Structures and Molecular Docking Analysis in EGFRs, Yang Jin, LiGong Yao, YueWei Guo, XuWen Li, 2022
- Diversity-oriented synthesis of marine polybrominated diphenyl ethers as potential KCNQ potassium channel activators, Liu, LaiXin, Gu, RuRong, Jin, Yang, Chen, XueQin, Li, XuWen, Zheng, YueMing, Gao, ZhaoBing, Guo, YueWei, 2022
- Dolabellane Diterpenoids from the Xisha Soft Coral Clavularia viridis, Gao, Yuan, Du, YeQing, Zang, Yi, Liu, HongChun, Wan, HaiYan, Li, Jia, Li, XuWen, Guo, YueWei, 2022
- Weizhouochrones: Gorgonian-Derived Symmetric Dimers and Their Structure Elucidation Using Anisotropic NMR Combined with DP4+Probability and CASE-3D, Li, XiaoLu, Ru, Tong, NavarroVazquez, Armando, Lindemann, Peter, Nazare, Marc, Li, XuWen, Guo, YueWei, Sun, Han, 2022
- Nitrogenous Sesquiterpenoids from the South China Sea Nudibranch Hexabranchus sanguineus and Its Possible Sponge-Prey Acanthella cavernosa: Chiral Separation, Stereochemistry and Chemical Ecology, Shen, ShouMao, Zhang, ZaiYong, Yao, LiGong, Wang, JianRong, Guo, YueWei, Li, XuWen, 2022
- Diversity-oriented synthesis of marine sponge derived hyrtioreticulins and their anti-inflammatory activities, Chen BoRu, Gao ChengLong, Liu Jin, Guo YueWei, Jiang JianLan, Pang Tao, Li XuWen, 2022
- Sinuhirtone A, An Uncommon 17,19-Dinorxeniaphyllanoid, and Nine Related New Terpenoids from the Hainan Soft Coral Sinularia hirta, Chen, ZiHui, Lu, SiQi, Han, GuanYing, Li, XuWen, Guo, YueWei, 2022
- Sinusiaetone A, an Anti-inflammatory Norditerpenoid with a Bicyclo11.3.0hexadecane Nucleus from the Hainan Soft Coral Sinularia siaesensis, Chen, ZiHui, Li, WangSheng, Zhang, ZaiYong, Luo, Hui, Wang, JianRong, Zhang, HaiYan, Zeng, ZiRong, Chen, Bao, Li, XuWen, Guo, YueWei, 2021
- Sinueretone A, a Diterpenoid with Unprecedented Tricyclo12.1.0.0(5,9) pentadecane Carbon Scaffold from the South China Sea Soft Coral Sinularia erecta, Liu, Jiao, Li, Heng, Wu, MengJun, Tang, Wei, Wang, JianRong, Gu, YuCheng, Wang, Hong, Li, XuWen, Guo, YueWei, 2021
- New formamidobisabolene-type sesquiterpenoids from a Hainan Sponge Halichondria sp., Chen, Bao, Li, WangSheng, Gu, YuCheng, Zhang, HaiYan, Luo, Hui, Wang, ChangYun, Guo, YueWei, Li, XuWen, 2021
- Sinunanolobatone A, an Anti-inflammatory Diterpenoid with Bicyclo13.1.0pentadecane Carbon Scaffold, and Related Casbanes from the Sanya Soft Coral Sinularia nanolobata, Zeng, ZiRong, Li, WangSheng, Nay, Bastien, Hu, Pei, Zhang, HaiYan, Wang, Hong, Li, XuWen, Guo, YueWei, 2021
- Uncommon Diterpenoids from the South China Sea Soft Coral Sinularia humilis and Their Stereochemistry, Sun, LiLi, Li, WangSheng, Li, Jie, Zhang, HaiYan, Yao, LiGong, Luo, Hui, Guo, YueWei, Li, XuWen, 2021
- Marine alkaloids as the chemical marker for the prey-predator relationship of the sponge Xestospongia sp. and the nudibranch Jorunna funebris, Wu, Qihao, Li, SongWei, de Voogd, Nicole J, Wang, Hong, Yao, LiGong, Guo, YueWei, Li, XuWen, 2021
- Diversity-oriented synthesis of cembranoid derivatives as potential anti-inflammatory agents, Zhang, Cong, Li, Heng, Liu, Jin, Liu, Moting, Zhang, Hao, Chen, KaiXian, Guo, YueWei, Tang, Wei, Li, XuWen, 2021
- Polyoxygenated anti-inflammatory biscembranoids from the soft coral Sarcophyton tortuosum and their stereochemistry, Li, Yufen, Li, Songwei, Cuadrado, Cristina, Gao, Chenglong, Wu, Qihao, Li, Xiaolu, Pang, Tao, Daranas, Antonio Hernandez, Guo, Yuewei, Li, Xuwen, 2021
- Uncommon Bis-quinolizidine Alkaloids from the Hainan Sponge Neopetrosia chaliniformis, Bao Chen, XiaJuan Huan, ZeHong Miao, Nicole Jde Voogd, YuCheng Gu, ChangYun Wang, YueWei Guo, XuWen Li, 2021
- Polyoxygenated Cembranoids from Soft Coral Lobophytum Crassum and Their Anti-tumoral Activities, FangZhou Yin, XiaJuan Huan, Wayan Mudianta, ZeHong Miao, Hong Wang, YueWei Guo, XuWen Li, 2021
- Unusual polyoxygenated casbane diterpenoids from the South China Sea soft coral Sinularia erecta, Liu, Jiao, Wu
Awards
- Sanofi-Youth Talent Award of the Chinese Academy of Sciences Shanghai Institute of Life Sciences (2017): First Prize
- Shanghai Pujiang Talent Program (2016): First Prize
- Member of the Youth Innovation Promotion Association of the Chinese Academy of Sciences (2016): First Prize
- Youth Talent Support Program of the China Association for Science and Technology (2016): First Prize
