Areas of Focus
- Natural Product Chemical Biology
- Natural Medicinal Chemistry
Work Experience
- 2022-01 - Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher
- 2016-01 - 2021-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher
- 2013-12 - 2015-12 - Kunming Institute of Botany, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2010-09--2013-07 Ph.D. in Science: Kunming Institute of Botany, Chinese Academy of Sciences
- 2007-09--2009-12 Master's in Medicine: Kunming University of Science and Technology
- 2003-09--2007-07 Bachelor's in Engineering: Kunming University of Science and Technology
- Published 45 papers in authoritative journals
- Received over ten national invention patents and one US patent
- Hosted three National Natural Science Foundation projects
Publications
- Research Progress on Drugs for the Treatment of Hepatitis C, DuoZhi Chen, XiaoJiang Hao, 2021
- Phenanthridine Derivative Host Heat Shock Cognate 70 Down-Regulators as Porcine Epidemic Diarrhea Virus Inhibitors, DuoZhi Chen, ShiRui Fan, BiJuan Yang, HuoChun Yao, YiTing Wang, JieYun Cai, ChenXu Jing, ZiHao Pan, Miao Luo, YanQiu Yuze, GuangJin Liu, XiaoJiang Hao, 2021
- Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L., WenJuan Yuan, WenFen Gao, JiangYu Zhao, Yu Zhang, DuoZhi Chen, ShunLin Li, YingTong Di, XiaoJiang Hao, 2020
- Two new bioactive lignans from leaves and twigs of Cleistanthus concinnus Croizat, ShiRui Fan, Jingjing Guo, YiTing Wang, BiJuan Yang, DuoZhi Chen, XiaoJiang Hao, 2020
- Aphananoid A is an Anti-Inflammatory Limonoid with a New 5/6/5 Fused Ring Featuring a C-24 Carbon Skeleton from Aphanamixis polystachya, BiJuan Yang, ShiRui Fan, JieYun Cai, YiTing Wang, Chenxu Jing, Jingjing Guo, DuoZhi Chen, XiaoJiang Hao, 2020
- Stelleraguaianone B and C, two new sesquiterpenoids from Stellera chamaejasme L., Chenxu Jing, Jingjing Guo, BiJuan Yang, ShiRui Fan, YiTing Wang, DuoZhi Chen, XiaoJiang Hao, 2019
- Structural Revision of Macropodumine A and Structure of 2-Deoxymacropodumine A, Daphniphyllum Alkaloids with 11-Membered Macrolactone Rings, Jiahui Zhang, Pei Cao, Yuanliang Ma, Xin Fang, Jing Yang, Yu Zhang, DuoZhi Chen, Yucheng Gu, Yingtong Di, XiaoJiang Hao, 2019
- Design, synthesis and structure-activity relationship optimization of phenanthridine derivatives as new Wnt/beta-catenin signalling pathway agonists, DuoZhi Chen, BiJuan Yang, Xiaoli He, ShiRui Fan, Jieyun Cai, Chenxu Jing, Heng Zhang, Yu Zhang, Lin Li, XiaoJiang Hao, 2019
- Cytotoxic indole alkaloids from Melodinus khasianus and Melodinus tenuicaudatus, Wenfang Yi, DuoZhi Chen, Xiao Ding, Xiaonian Li, Shunlin Li, Yingtong Di, Yu Zhang, XiaoJiang Hao, 2018
- Efficient synthesis of new phenanthridine Wnt/beta-catenin signaling pathway agonists, DuoZhi Chen, Heng Zhang, Chenxu Jing, Xiaoli He, BiJuan Yang, Jieyun Cai, Yunfu Zhou, Xiaoming Song, Lin Li, XiaoJiang Hao, 2018
- An Explorer of Chemical Biology of Plant Natural Products in Southwest China, Yuemao Shen, DuoZhi Chen, 2018
- Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum, YanRong Zeng, Ping Yi, Wei Gu, ChunXia Xiao, LieJun Huang, DongSong Tian, Hui Yan, DuoZhi Chen, ChunMao Yuan, XiaoJiang Hao, 2018
- Hypermonins A and B, two 6-norpolyprenylated acylphloroglucinols with unprecedented skeletons from Hypericum monogynum, Chun-Mao Yuan, Yan-Rong Zeng, Ping Yi, Wei Gu, Chun-Xia Xiao, Lie-Jun Huang, Dong-Song Tian, Hui Yan, Duo-Zhi Chen, Xiao-Jiang Hao, 2018
- Rapid synthesis of ismine, a bioactive amaryllidaceae alkaloid, Jingjing Guo, BiJuan Yang, Chenxu Jing, DuoZhi Chen, Xiaojiang Hao, 2017
- (+/-)-Perforison A, A Pair of New Chromone Enantiomers from Harrisonia perforata, WenJuan Yuan, WenFen Gao, JiaHui Zhang, Pei Cao, Yu Zhang, DuoZhi Chen, ShunLin Li, YingTong Di, XiaoJiang Hao, 2017
- Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of Bisebracteolasin A, WenJuan Yuan, Xiao Ding, Zhe Wang, BiJuan Yang, XiaoNian Li, Yu Zhang, DuoZhi Chen, ShunLin Li, Quan Chen, YingTong Di, Haji Akber Aisa, XiaoJiang Hao, 2017
- Design, Synthesis, and Structural Optimization of Lycorine-Derived Phenanthridine Derivatives as Wnt/beta-Catenin Signaling Pathway Agonists, DuoZhi Chen, ChenXu Jing, JieYun Cai, JiBo Wu, Sheng Wang, Jun Lin Yin, XiaoNian Li, Lin Li, XiaoJiang Hao, 2016
- Three new diterpenes with cytotoxic activity from the roots of Euphorbia ebracteolata Hayata, WenJuan Yuan, GuoPing Yang, JiaHui Zhang, Yu Zhang, DuoZhi Chen, ShunLin Li, YingTong Di, XiaoJiang Hao, 2016
- Four new tetracyclic alkaloids with cis-decahydroquinoline motif from Myrioneuron effusum, JiaHui Zhang, JingGuo Jing, Yu Xi Yuan, YanHui Fu, YuCheng Gu, Yu Zhang, DuoZhi Chen, ShunLin Li, YingTong Di, XiaoJiang Hao, 2016
- Lycorine-derived phenanthridine downregulators of host Hsc70 as potential hepatitis C virus inhibitors, DuoZhi Chen, JieYun Cai, Junlin Yin, Jiandong Jiang, Chenxu Jing, Yanping Zhu, Junjun Cheng, YingTong Di, Yu Zhang, Mingming Cao, Shunlin Li, Zonggen Peng, Xiaojiang Hao, 2015
- New vobasinyl-ibogan type bisindole alkaloids from Tabernaemontana corymbosa, Yu Zhang, Lingli Guo, Guangmei Yang, Feng Guo, YingTong Di, Shunlin Li, DuoZhi Chen, Xiaojiang Hao, 2015
- Bioactive Limonoid Constituents of Munronia henryi, Ying Yan, JianXin Zhang, Tao Huang, XinYing Mao, Wei Gu, HongPing He, YingTong Di, ShunLin Li, DuoZhi Chen, Yu Zhang, XiaoJiang Hao, 2015
- Synthesis of 4-ethyl-5-methyl-5,6-dihydrophenanthridine-8,9-diol as the key intermediate of potent agonists of the Wnt signalling pathway, Chenxu Jing, Jieyun Cai, Yu Zhang, DuoZhi Chen, Xiaojiang Hao, 2015
- New Phragmalin-Type Limonoid Orthoesters from the Bark of Chukrasia tabularis var. velutina, WenXing Liu, DuoZhi Chen, JiaYin Ding, XiaoJiang Hao, ShunLin Li, 2015
- Alkaloids with Different Carbon Units from Myrioneuron faberi, MingMing Cao, Yu Zhang, ShengDian Huang, YingTong Di, ZongGen Peng, JianDong Jiang, ChunMao Yuan, DuoZhi Chen, ShunLin Li, HongPing He, XiaoJiang Hao, 2015
- Design, Synthesis and Structure-Activity Relationship Optimization of Lycorine Derivatives for HCV Inhibition, DuoZhi Chen, Jieyun Cai, Junjun Cheng, Chenxu Jing, Junlin Yin, Jiandong Jiang, Zonggen Peng, Xiaojiang Hao, 2015
- Spiramine derivatives induce apoptosis of Bax(-/-)/Bak(-/-) cell and cancer cells, Chen Yan, Li Huang, HongChun Liu, DuoZhi Chen, HaiYang Liu, XiaoHui Li, Yu Zhang, MeiYu Geng, Quan Chen, XiaoJiang Hao, 2014
- Limonoids from Aphanamixis polystachya and Their Antifeedant Activity, JieYun Cai, DuoZhi Chen, ShiHong Luo, NingChuan Kong, Yu Zhang, YingTong Di, Qiang Zhang, Juan Hua, ShuXi Jing, ShunLin Li, ShengHong Li, XiaoJiang Hao, HongPing He, 2014
- Cyclohexane-Fused Octahydroquinolizine Alkaloids from Myrioneuron faberi with Activity against Hepatitis C Virus, MingMing Cao, Yu Zhang, XiaoHui Li, ZongGen Peng, JianDong Jiang, YuCheng Gu, YingTong Di, XiaoNian Li, DuoZhi Chen, ChengFeng Xia, HongPing He, ShunLin Li, XiaoJiang Hao, 2014
- A new Amaryllidaceae alkaloid from the bulbs of Lycoris radiata, ShengDian Huang, Yu Zhang, HongPing He, ShiFei Li, GuiHua Tang, DuoZhi Chen, MingMing Cao, YingTong Di, XiaoJiang Hao, 2013
- Small-molecule modulation of Wnt signaling via modulating the Axin-LRP5/6 interaction, Sheng Wang, Junlin Yin, DuoZhi Chen, Fen Nie, Xiaomin Song, Cong Fei, Haofei M
