Areas of Focus
- Biosafety
- Pathogenic Microorganisms
Work Experience
- 2022-06~2024-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Director of P3 Laboratory/Master's Supervisor
- 2021-01~2022-06 - Kunming Institute of Zoology, Chinese Academy of Sciences - Deputy Director/Senior Engineer
- 2014-12~2020-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Deputy Director/Engineer
- 2008-08~2014-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Engineer
- 2006-06~2007-07 - Kunming Institute of Zoology, Chinese Academy of Sciences - Research Intern
Academic Background & Achievements
- 2003-09--2006-06 Master's Degree: Jilin Agricultural University
- 1999-09--2003-06 Bachelor's Degree: Jilin Agricultural University
Publications
- Differential pathogenic and molecular features in neurological infection of SARS-CoV-2 Omicron BA.5.2 and BA.2.75 and Delta, Minghua Li, 2024
- SARS-CoV-2 nonstructural protein 6 triggers endoplasmic reticulum stress-induced autophagy to degrade STING1, Minghua Li, 2023
- SARS-CoV-2 Spike protein S2 subunit modulates gamma-secretase and enhances amyloid-beta production in COVID-19 neuropathy, Minghua Li, 2022
- Characteristics of replication and pathogenicity of SARS-CoV-2 Alpha and Delta isolates, Minghua Li, 2022
- Fast and long-lasting immune response to S-trimer COVID-19 vaccine adjuvanted by PIKA, Minghua Li, 2021
- Northern pig-tailed macaques (Macaca leonina) infected with SARS-CoV-2 show rapid viral clearance and persistent immune response, Minghua Li, 2021
- Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice, Minghua Li, 2021
- Biomimetic Human Disease Model of SARS-CoV-2-Induced Lung Injury and Immune Responses on Organ Chip System, Minghua Li, 2021
- Delayed severe cytokine storm and immune cell infiltration in SARS-CoV-2-infected aged Chinese rhesus macaques, Minghua Li, 2020
- A new species of Ophiocordyceps (Clavicipitales, Ascomycota) from southwestern China, Minghua Li, 2011
- The value of nonhuman primate animal models in anti-HIV drug studies, Minghua Li, 2007
- Application of AIDS Macaque Animal Model in HIV Vaccine Research, Minghua Li, 2007
- Establishment of AIDS Animal Model with SIVmac239 Infected Chinese Rhesus Monkey, Minghua Li, 2007
- Nonhuman Primate Models in AIDS Research, Minghua Li, 2005
Awards
- 2022: 'Kunming Institute of Zoology Biosafety Level 3 Laboratory' received the first Youth May Fourth Medal Collective Commendation from the Chinese Academy of Sciences
- 2021: 'Kunming Institute of Zoology COVID-19 Animal Model Research Team' received the Advanced Collective Commendation from the Ministry of Science and Technology
- 2020: Outstanding Communist Party Member of the Chinese Academy of Sciences
- 2020: 'Temporary Party Branch for Emergency Research on COVID-19 at Kunming Institute of Zoology' received the Advanced Grassroots Party Organization Commendation from the Chinese Academy of Sciences
