Professor | Guo-Bin Cai | Asia Growth Partners

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Name	Guo-Bin Cai
Contact Information	gbcai2011@whu.edu.cn
Language ability	Chinese, English
Province	Hubei

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Name

Guo-Bin Cai

Contact Information

gbcai2011@whu.edu.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	Wuhan University
Faculty	Medical School
Academic Background & Achievements	2003-2007: PhD in Pathogen Biology, Wuhan University 2000-2003: Master's in Pathogen Biology, Wuhan University 1990-1994: Bachelor's in Biology, Wuhan University Hosted 1 Hubei Provincial Natural Science Foundation project, 2 Hubei Provincial Health Department special funds, 1 sub-project of the National Natural Science Foundation of China, and 1 project funded by the fundamental research funds for the central universities
Work Experience	2011.03-2012.05: Postdoctoral Researcher, Department of Pharmacology, Baylor College of Medicine, USA 2008.12-present: Associate Professor, Department of Pathogen Biology, Wuhan University 2004.03-2006.10: Exchange Scholar, Department of Molecular Parasitology, Sungkyunkwan University, South Korea 1999-2008.11: Lecturer, Department of Pathogen Biology, Wuhan University 1994.07-1999.11: Assistant, Department of Human Parasitology, Hubei Medical University
Awards	Third Prize of Natural Science Award of Hubei Province

University/Lab Affiliation and Title

Wuhan University

Faculty

Medical School

Academic Background & Achievements

2003-2007: PhD in Pathogen Biology, Wuhan University
2000-2003: Master's in Pathogen Biology, Wuhan University
1990-1994: Bachelor's in Biology, Wuhan University
Hosted 1 Hubei Provincial Natural Science Foundation project, 2 Hubei Provincial Health Department special funds, 1 sub-project of the National Natural Science Foundation of China, and 1 project funded by the fundamental research funds for the central universities

Work Experience

2011.03-2012.05: Postdoctoral Researcher, Department of Pharmacology, Baylor College of Medicine, USA
2008.12-present: Associate Professor, Department of Pathogen Biology, Wuhan University
2004.03-2006.10: Exchange Scholar, Department of Molecular Parasitology, Sungkyunkwan University, South Korea
1999-2008.11: Lecturer, Department of Pathogen Biology, Wuhan University
1994.07-1999.11: Assistant, Department of Human Parasitology, Hubei Medical University

Awards

Third Prize of Natural Science Award of Hubei Province

Areas of Focus	Parasite reproduction and physiology research Small molecule drug screening and its anti-pathogen mechanisms
Publications	A membrane-associated metalloprotease of Schistosoma japonicum structurally related to the FACE-1/Ste24p protease family, Ying Zhang, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2019 Isolation and characterization of a novel serine protease inhibitor, SjSPI, from Schistosoma japonicum, Ying Zhang, Jin Guo, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2018 Functionally Expression of Metalloproteinase in Taenia solium Metacestode and Its Evaluation for Serodiagnosis of Cysticercosis, Ying ZHANG, Young-An BAE, Hong-Ying ZONG, Yoon KONG, Guo-Bin CAI (Correspondence), 2016 Expression and characterization of a phospholipid hydroperoxide glutathione peroxidase gene in Schistosoma japonicum, YING ZHANG, YUAN HE, LI HE, HONGYING ZONG and GUOBIN CAI (Correspondence), 2015 Molecular cloning and characterization of a phospholipid hydroperoxide glutathione peroxidase gene from a blood fluke Schistosoma japonicum, Ying Zhang, Yuan He, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2015 Antimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase, Xue Jian, Diao Jiasheng (Co-first), Guobin Cai (Co-first), Lisheng Deng, Yongcheng Song, 2013 Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase, Guobin Cai, Lisheng Deng, Jian Xue, Silvia N.J. Moreno, Boris Striepen, Yongcheng Song, 2013 Thermodynamic Investigations of Inhibitor Binding to 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase, Guobin Cai, Lisheng Deng, Bartlomiej G. Fryszczyn, Nicholas G. Brown, Zhen Liu, Hong Jiang, Timothy Palzkill, and Yongcheng Song, 2012 Vitellocyte-specific expression of phospholipid hydroperoxide glutathione peroxidases in Clonorchis sinensis, Guo-Bin Cai, Young-An Bae, Seon-Hee Kim, Woon-Mok Sohn, Yoon-Song Lee, Ming-Sen Jiang, Tong-Soo Kim, Yoon Kong, 2008

Areas of Focus

Parasite reproduction and physiology research
Small molecule drug screening and its anti-pathogen mechanisms

Publications

A membrane-associated metalloprotease of Schistosoma japonicum structurally related to the FACE-1/Ste24p protease family, Ying Zhang, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2019
Isolation and characterization of a novel serine protease inhibitor, SjSPI, from Schistosoma japonicum, Ying Zhang, Jin Guo, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2018
Functionally Expression of Metalloproteinase in Taenia solium Metacestode and Its Evaluation for Serodiagnosis of Cysticercosis, Ying ZHANG, Young-An BAE, Hong-Ying ZONG, Yoon KONG, Guo-Bin CAI (Correspondence), 2016
Expression and characterization of a phospholipid hydroperoxide glutathione peroxidase gene in Schistosoma japonicum, YING ZHANG, YUAN HE, LI HE, HONGYING ZONG and GUOBIN CAI (Correspondence), 2015
Molecular cloning and characterization of a phospholipid hydroperoxide glutathione peroxidase gene from a blood fluke Schistosoma japonicum, Ying Zhang, Yuan He, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2015
Antimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase, Xue Jian, Diao Jiasheng (Co-first), Guobin Cai (Co-first), Lisheng Deng, Yongcheng Song, 2013
Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase, Guobin Cai, Lisheng Deng, Jian Xue, Silvia N.J. Moreno, Boris Striepen, Yongcheng Song, 2013
Thermodynamic Investigations of Inhibitor Binding to 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase, Guobin Cai, Lisheng Deng, Bartlomiej G. Fryszczyn, Nicholas G. Brown, Zhen Liu, Hong Jiang, Timothy Palzkill, and Yongcheng Song, 2012
Vitellocyte-specific expression of phospholipid hydroperoxide glutathione peroxidases in Clonorchis sinensis, Guo-Bin Cai, Young-An Bae, Seon-Hee Kim, Woon-Mok Sohn, Yoon-Song Lee, Ming-Sen Jiang, Tong-Soo Kim, Yoon Kong, 2008

Parasite Reproduction Physiology Drug Screening Molecular Mechanisms Pathogens Enzyme Inhibition Molecular Structure Biological Pathways Disease Control

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