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Guo-Bin Cai
Medical School
Wuhan University
Hubei
Language: Chinese, English
Parasite
Reproduction
Physiology
Drug Screening
Molecular Mechanisms
Pathogens
Enzyme Inhibition
Molecular Structure
Biological Pathways
Disease Control
Areas of Focus
- Parasite reproduction and physiology research
- Small molecule drug screening and its anti-pathogen mechanisms
Work Experience
- 2011.03-2012.05: Postdoctoral Researcher, Department of Pharmacology, Baylor College of Medicine, USA
- 2008.12-present: Associate Professor, Department of Pathogen Biology, Wuhan University
- 2004.03-2006.10: Exchange Scholar, Department of Molecular Parasitology, Sungkyunkwan University, South Korea
- 1999-2008.11: Lecturer, Department of Pathogen Biology, Wuhan University
- 1994.07-1999.11: Assistant, Department of Human Parasitology, Hubei Medical University
Academic Background & Achievements
- 2003-2007: PhD in Pathogen Biology, Wuhan University
- 2000-2003: Master's in Pathogen Biology, Wuhan University
- 1990-1994: Bachelor's in Biology, Wuhan University
- Hosted 1 Hubei Provincial Natural Science Foundation project, 2 Hubei Provincial Health Department special funds, 1 sub-project of the National Natural Science Foundation of China, and 1 project funded by the fundamental research funds for the central universities
Publications
- A membrane-associated metalloprotease of Schistosoma japonicum structurally related to the FACE-1/Ste24p protease family, Ying Zhang, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2019
- Isolation and characterization of a novel serine protease inhibitor, SjSPI, from Schistosoma japonicum, Ying Zhang, Jin Guo, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2018
- Functionally Expression of Metalloproteinase in Taenia solium Metacestode and Its Evaluation for Serodiagnosis of Cysticercosis, Ying ZHANG, Young-An BAE, Hong-Ying ZONG, Yoon KONG, Guo-Bin CAI (Correspondence), 2016
- Expression and characterization of a phospholipid hydroperoxide glutathione peroxidase gene in Schistosoma japonicum, YING ZHANG, YUAN HE, LI HE, HONGYING ZONG and GUOBIN CAI (Correspondence), 2015
- Molecular cloning and characterization of a phospholipid hydroperoxide glutathione peroxidase gene from a blood fluke Schistosoma japonicum, Ying Zhang, Yuan He, Li He, Hong-Ying Zong, Guo-Bin Cai (Correspondence), 2015
- Antimalarial and Structural Studies of Pyridine-Containing Inhibitors of 1-Deoxyxylulose-5-phosphate Reductoisomerase, Xue Jian, Diao Jiasheng (Co-first), Guobin Cai (Co-first), Lisheng Deng, Yongcheng Song, 2013
- Expression, characterization and inhibition of Toxoplasma gondii 1-deoxy-D-xylulose-5-phosphate reductoisomerase, Guobin Cai, Lisheng Deng, Jian Xue, Silvia N.J. Moreno, Boris Striepen, Yongcheng Song, 2013
- Thermodynamic Investigations of Inhibitor Binding to 1-Deoxy-D-Xylulose-5-Phosphate Reductoisomerase, Guobin Cai, Lisheng Deng, Bartlomiej G. Fryszczyn, Nicholas G. Brown, Zhen Liu, Hong Jiang, Timothy Palzkill, and Yongcheng Song, 2012
- Vitellocyte-specific expression of phospholipid hydroperoxide glutathione peroxidases in Clonorchis sinensis, Guo-Bin Cai, Young-An Bae, Seon-Hee Kim, Woon-Mok Sohn, Yoon-Song Lee, Ming-Sen Jiang, Tong-Soo Kim, Yoon Kong, 2008
Awards
- Third Prize of Natural Science Award of Hubei Province
