Professor | Jingyi Li | Asia Growth Partners

Name	Jingyi Li
Contact Information	lijingyi@ioz.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Jingyi Li

Contact Information

lijingyi@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2012-09--2017-06 PhD: Peking University 2008-09--2012-06 Bachelor: Hebei Agricultural University
Work Experience	2019-09~Present - Institute of Zoology, Chinese Academy of Sciences - Associate Researcher 2017-07~2019-08 - Institute of Biophysics, Chinese Academy of Sciences - Project Associate Researcher
Awards	Chinese Medical Science and Technology Award, Second Prize, Ministerial Level, 2021 Outstanding Scientific Achievement Award of the Chinese Academy of Sciences, Ministerial Level, 2020 Beijing Science and Technology Award, Second Prize, Provincial Level, 2018

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2012-09--2017-06 PhD: Peking University
2008-09--2012-06 Bachelor: Hebei Agricultural University

Work Experience

2019-09~Present - Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
2017-07~2019-08 - Institute of Biophysics, Chinese Academy of Sciences - Project Associate Researcher

Awards

Chinese Medical Science and Technology Award, Second Prize, Ministerial Level, 2021
Outstanding Scientific Achievement Award of the Chinese Academy of Sciences, Ministerial Level, 2020
Beijing Science and Technology Award, Second Prize, Provincial Level, 2018

Areas of Focus	Functional Genomics of Aging
Publications	Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor., Zunpeng Liu, Wei Li, Lingling Geng, Liang Sun, Qiaoran Wang, Yang Yu, Pengze Yan, Chuqian Liang, Jie Ren, Moshi Song, Qian Zhao, Jinghui Lei, Yusheng Cai, Jiaming Li, Kaowen Yan, Zeming Wu, Qun Chu, Jingyi Li, Si Wang, Chunyi Li, JingDong J Han, Reyna HernandezBenitez, Ng ShyhChang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, GuangHui Liu., 2022 Destabilizing heterochromatin by APOE mediates senescence., Hongkai Zhao, Qianzhao Ji, Zeming Wu, Si Wang, Jie Ren, Kaowen Yan, Zehua Wang, Jianli Hu, Qun Chu, Huifang Hu, Yusheng Cai, Qiaoran Wang, Daoyuan Huang, Zhejun Ji, Juan Carlos Izpisua Belmonte, Jingyi Li, Moshi Song, Weiqi Zhang, Jing Qu, Guang-Hui Liu., 2022 The landscape of aging., Yusheng Cai, Wei Song, Jiaming Li, Ying Jing, Chuqian Liang, Liyuan Zhang, Xia Zhang, Wenhui Zhang, Beibei Liu, Yongpan An, Jingyi Li, Baixue Tang, Siyu Pei, Xueying Wu, Yuxuan Liu, ChengLe Zhuang, Yilin Ying, Xuefeng Dou, Yu Chen, FuHui Xiao, Dingfeng Li, Ruici Yang, Ya Zhao, Yang Wang, Lihui Wang, Yujing Li, Shuai Ma, Si Wang, Xiaoyuan Song, Jie Ren, Liang Zhang, Jun Wang, Weiqi Zhang, Zhengwei Xie, Jing Qu, Jianwei Wang, Yichuan Xiao, Ye Tian, Gelin Wang, Ping Hu, Jing Ye, Yu Sun, Zhiyong Mao, QingPeng Kong, Qiang Liu, Weiguo Zou, XiaoLi Tian, ZhiXiong Xiao, Yong Liu, JunPing Liu, Moshi Song, JingDong J Han, GuangHui Liu., 2022 A single-cell transcriptomic atlas of primate pancreatic islet aging., Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Belmonte, Juan Carlos Izpisua, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, GuangHui, Tang, Fuchou, Qu, Jing., 2021 A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence., Wang, Wei, Zheng, Yuxuan, Sun, Shuhui, Li, Wei, Song, Moshi, Ji, Qianzhao, Wu, Zeming, Liu, Zunpeng, Fan, Yanling, Liu, Feifei, Li, Jingyi, Esteban, Concepcion Rodriguez, Wang, Si, Zhou, Qi, Belmonte, Juan Carlos Izpisua, Zhang, Weiqi, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2021 Single-Cell Transcriptomic Atlas of Primate Ovarian Aging., Wang, Si, Zheng, Yuxuan, Li, Jingyi, Yu, Yang, Zhang, Weiqi, Song, Moshi, Liu, Zunpeng, Min, Zheying, Hu, Huifang, Jing, Ying, He, Xiaojuan, Sun, Liang, Ma, Lifang, Esteban, Concepcion Rodriguez, Chan, Piu, Qiao, Jie, Zhou, Qi, Belmonte, Juan Carlos Izpisua, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2020 A single-cell transcriptomic landscape of primate arterial aging., Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song, Jingyi Li, Jinghui Lei, Huize Pan, Si Wang, Xibo Ma, Shuai Ma, Hongyu Li, Fei Sun, Haifeng Wan, Wei Li, Piu Chan, Qi Zhou, GuangHui Liu, Fuchou Tang, Jing Qu., 2020 Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing., Li, Jingyi, Zhou, Xin, Liu, Xiaomeng, Ren, Jie, Wang, Jilian, Wang, Wendong, Zheng, Yuxuan, Shi, Xinyun, Sun, Tao, Li, Zhifei, Kang, Anding, Tang, Fuchou, Wen, Lu, Fu, Wei., 2019 Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)., Liu, Xiaomeng, Ren, Jie, Luo, Nan, Guo, Huahu, Zheng, Yuxuan, Li, Jingyi, Tang, Fuchou, Wen, Lu, Peng, Jirun., 2019 Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis., Liping Deng, Ruotong Ren, Zunpeng Liu, Moshi Song, Jingyi Li, Zeming Wu, Xiaoqing Ren, Lina Fu, Wei Li, Weiqi Zhang, Pedro Guillen, Juan Carlos Izpisua Belmonte, Piu Chan, Jing Qu, GuangHui Liu., 2019 CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-B/RelA in maintaining the homeostasis of human vascular cells., Wang, Ping, Liu, Zunpeng, Zhang, Xiaoqian, Li, Jingyi, Sun, Liang, Ju, Zhenyu, Li, Jian, Chan, Piu, Liu, GuangHui, Zhang, Weiqi, Song, Moshi, Qu, Jing., 2018 Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding., Yang, Jiping, Li, Jingyi, Suzuki, Keiichiro, Liu, Xiaomeng, Wu, Jun, Zhang, Weiqi, Ren, Ruotong, Zhang, Weizhou, Chan, Piu, Belmonte, Juan Carlos Izpisua, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2017 SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2., Pan, Huize, Guan, Di, Liu, Xiaomeng, Li, Jingyi, Wang, Lixia, Wu, Jun, Zhou, Junzhi, Zhang, Weizhou, Ren, Ruotong, Zhang, Weiqi, Li, Ying, Yang, Jiping, Hao, Ying, Yuan, Tingting, Yuan, Guohong, Wang, Hu, Ju, Zhenyu, Mao, Zhiyong, Li, Jian, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2016 PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype., Duan, Shunlei, Yuan, Guohong, Liu, Xiaomeng, Ren, Ruotong, Li, Jingyi, Zhang, Weizhou, Wu, Jun, Xu, Xiuling, Fu, Lina, Li, Ying, Yang, Jiping, Bai, Ruijun, Yi, Fei, Suzuki, Keiichiro, Gao, Hua, Esteban, Concepcion Rodriguez, Zhang, Chuanbao, Belmonte, Juan Carlos Izpisua, Chen, Zhiguo, Wang, Xiaomin, Jiang, Tao, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2015 Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients., Wen, Lu, Li, Jingyi, Guo, Huahu, Liu, Xiaomeng, Zheng, Shengmin, Zhang, Dafang, Zhu, Weihua, Qu, Jianhui, Guo, Limin, Du, Dexiao, Jin, Xiao, Zhang, Yuhao, Gao, Yun, Shen, Jie, Ge, Hao, Tang, Fuchou, Huang, Yanyi, Peng, Jirun., 2015 A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging., Zhang, Weiqi, Li, Jingyi, Suzuki, Keiichiro, Qu, Jing, Wang, Ping, Zhou, Junzhi, Liu, Xiaomeng, Ren, Ruotong, Xu, Xiuling, Ocampo, Alejandro, Yuan, Tingting, Yang, Jiping, Li, Ying, Shi, Liang, Guan, Dee, Pan, Huize, Duan, Shunlei, Ding, Zhichao, Li, Mo, Yi, Fei, Bai, Ruijun, Wang, Yayu, Chen, Chang, Yang, Fuquan, Li, Xiaoyu, Wang, Zimei, Aizawa, Emi, Goebl, April, Soligalla, Rupa Devi, Reddy, Pradeep, Esteban, Concepcion Rodriguez, Tang, Fuchou, Liu, GuangHui, Belmonte, Juan Carlos Izpisua., 2015

Areas of Focus

Functional Genomics of Aging

Publications

Cross-species metabolomic analysis identifies uridine as a potent regeneration promoting factor., Zunpeng Liu, Wei Li, Lingling Geng, Liang Sun, Qiaoran Wang, Yang Yu, Pengze Yan, Chuqian Liang, Jie Ren, Moshi Song, Qian Zhao, Jinghui Lei, Yusheng Cai, Jiaming Li, Kaowen Yan, Zeming Wu, Qun Chu, Jingyi Li, Si Wang, Chunyi Li, JingDong J Han, Reyna HernandezBenitez, Ng ShyhChang, Juan Carlos Izpisua Belmonte, Weiqi Zhang, Jing Qu, GuangHui Liu., 2022
Destabilizing heterochromatin by APOE mediates senescence., Hongkai Zhao, Qianzhao Ji, Zeming Wu, Si Wang, Jie Ren, Kaowen Yan, Zehua Wang, Jianli Hu, Qun Chu, Huifang Hu, Yusheng Cai, Qiaoran Wang, Daoyuan Huang, Zhejun Ji, Juan Carlos Izpisua Belmonte, Jingyi Li, Moshi Song, Weiqi Zhang, Jing Qu, Guang-Hui Liu., 2022
The landscape of aging., Yusheng Cai, Wei Song, Jiaming Li, Ying Jing, Chuqian Liang, Liyuan Zhang, Xia Zhang, Wenhui Zhang, Beibei Liu, Yongpan An, Jingyi Li, Baixue Tang, Siyu Pei, Xueying Wu, Yuxuan Liu, ChengLe Zhuang, Yilin Ying, Xuefeng Dou, Yu Chen, FuHui Xiao, Dingfeng Li, Ruici Yang, Ya Zhao, Yang Wang, Lihui Wang, Yujing Li, Shuai Ma, Si Wang, Xiaoyuan Song, Jie Ren, Liang Zhang, Jun Wang, Weiqi Zhang, Zhengwei Xie, Jing Qu, Jianwei Wang, Yichuan Xiao, Ye Tian, Gelin Wang, Ping Hu, Jing Ye, Yu Sun, Zhiyong Mao, QingPeng Kong, Qiang Liu, Weiguo Zou, XiaoLi Tian, ZhiXiong Xiao, Yong Liu, JunPing Liu, Moshi Song, JingDong J Han, GuangHui Liu., 2022
A single-cell transcriptomic atlas of primate pancreatic islet aging., Li, Jingyi, Zheng, Yuxuan, Yan, Pengze, Song, Moshi, Wang, Si, Sun, Liang, Liu, Zunpeng, Ma, Shuai, Belmonte, Juan Carlos Izpisua, Chan, Piu, Zhou, Qi, Zhang, Weiqi, Liu, GuangHui, Tang, Fuchou, Qu, Jing., 2021
A genome-wide CRISPR-based screen identifies KAT7 as a driver of cellular senescence., Wang, Wei, Zheng, Yuxuan, Sun, Shuhui, Li, Wei, Song, Moshi, Ji, Qianzhao, Wu, Zeming, Liu, Zunpeng, Fan, Yanling, Liu, Feifei, Li, Jingyi, Esteban, Concepcion Rodriguez, Wang, Si, Zhou, Qi, Belmonte, Juan Carlos Izpisua, Zhang, Weiqi, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2021
Single-Cell Transcriptomic Atlas of Primate Ovarian Aging., Wang, Si, Zheng, Yuxuan, Li, Jingyi, Yu, Yang, Zhang, Weiqi, Song, Moshi, Liu, Zunpeng, Min, Zheying, Hu, Huifang, Jing, Ying, He, Xiaojuan, Sun, Liang, Ma, Lifang, Esteban, Concepcion Rodriguez, Chan, Piu, Qiao, Jie, Zhou, Qi, Belmonte, Juan Carlos Izpisua, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2020
A single-cell transcriptomic landscape of primate arterial aging., Weiqi Zhang, Shu Zhang, Pengze Yan, Jie Ren, Moshi Song, Jingyi Li, Jinghui Lei, Huize Pan, Si Wang, Xibo Ma, Shuai Ma, Hongyu Li, Fei Sun, Haifeng Wan, Wei Li, Piu Chan, Qi Zhou, GuangHui Liu, Fuchou Tang, Jing Qu., 2020
Detection of Colorectal Cancer in Circulating Cell-Free DNA by Methylated CpG Tandem Amplification and Sequencing., Li, Jingyi, Zhou, Xin, Liu, Xiaomeng, Ren, Jie, Wang, Jilian, Wang, Wendong, Zheng, Yuxuan, Shi, Xinyun, Sun, Tao, Li, Zhifei, Kang, Anding, Tang, Fuchou, Wen, Lu, Fu, Wei., 2019
Comprehensive DNA methylation analysis of tissue of origin of plasma cell-free DNA by methylated CpG tandem amplification and sequencing (MCTA-Seq)., Liu, Xiaomeng, Ren, Jie, Luo, Nan, Guo, Huahu, Zheng, Yuxuan, Li, Jingyi, Tang, Fuchou, Wen, Lu, Peng, Jirun., 2019
Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis., Liping Deng, Ruotong Ren, Zunpeng Liu, Moshi Song, Jingyi Li, Zeming Wu, Xiaoqing Ren, Lina Fu, Wei Li, Weiqi Zhang, Pedro Guillen, Juan Carlos Izpisua Belmonte, Piu Chan, Jing Qu, GuangHui Liu., 2019
CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-B/RelA in maintaining the homeostasis of human vascular cells., Wang, Ping, Liu, Zunpeng, Zhang, Xiaoqian, Li, Jingyi, Sun, Liang, Ju, Zhenyu, Li, Jian, Chan, Piu, Liu, GuangHui, Zhang, Weiqi, Song, Moshi, Qu, Jing., 2018
Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding., Yang, Jiping, Li, Jingyi, Suzuki, Keiichiro, Liu, Xiaomeng, Wu, Jun, Zhang, Weiqi, Ren, Ruotong, Zhang, Weizhou, Chan, Piu, Belmonte, Juan Carlos Izpisua, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2017
SIRT6 safeguards human mesenchymal stem cells from oxidative stress by coactivating NRF2., Pan, Huize, Guan, Di, Liu, Xiaomeng, Li, Jingyi, Wang, Lixia, Wu, Jun, Zhou, Junzhi, Zhang, Weizhou, Ren, Ruotong, Zhang, Weiqi, Li, Ying, Yang, Jiping, Hao, Ying, Yuan, Tingting, Yuan, Guohong, Wang, Hu, Ju, Zhenyu, Mao, Zhiyong, Li, Jian, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2016
PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype., Duan, Shunlei, Yuan, Guohong, Liu, Xiaomeng, Ren, Ruotong, Li, Jingyi, Zhang, Weizhou, Wu, Jun, Xu, Xiuling, Fu, Lina, Li, Ying, Yang, Jiping, Bai, Ruijun, Yi, Fei, Suzuki, Keiichiro, Gao, Hua, Esteban, Concepcion Rodriguez, Zhang, Chuanbao, Belmonte, Juan Carlos Izpisua, Chen, Zhiguo, Wang, Xiaomin, Jiang, Tao, Qu, Jing, Tang, Fuchou, Liu, GuangHui., 2015
Genome-scale detection of hypermethylated CpG islands in circulating cell-free DNA of hepatocellular carcinoma patients., Wen, Lu, Li, Jingyi, Guo, Huahu, Liu, Xiaomeng, Zheng, Shengmin, Zhang, Dafang, Zhu, Weihua, Qu, Jianhui, Guo, Limin, Du, Dexiao, Jin, Xiao, Zhang, Yuhao, Gao, Yun, Shen, Jie, Ge, Hao, Tang, Fuchou, Huang, Yanyi, Peng, Jirun., 2015
A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging., Zhang, Weiqi, Li, Jingyi, Suzuki, Keiichiro, Qu, Jing, Wang, Ping, Zhou, Junzhi, Liu, Xiaomeng, Ren, Ruotong, Xu, Xiuling, Ocampo, Alejandro, Yuan, Tingting, Yang, Jiping, Li, Ying, Shi, Liang, Guan, Dee, Pan, Huize, Duan, Shunlei, Ding, Zhichao, Li, Mo, Yi, Fei, Bai, Ruijun, Wang, Yayu, Chen, Chang, Yang, Fuquan, Li, Xiaoyu, Wang, Zimei, Aizawa, Emi, Goebl, April, Soligalla, Rupa Devi, Reddy, Pradeep, Esteban, Concepcion Rodriguez, Tang, Fuchou, Liu, GuangHui, Belmonte, Juan Carlos Izpisua., 2015

Aging Functional Genomics Multi-Omics Disease Mechanisms Intervention Targets Stem Cells Organ Aging Primate Models Genetic Research Biological Aging

Yueshan Lei - Wuhan University

Jing Qu - University of Chinese Academy of Sciences

Xuefeng Duan - University of Chinese Academy of Sciences

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