Professor | Xuefeng Duan | Asia Growth Partners

Name	Xuefeng Duan
Contact Information	duanxf@im.ac.cn
Language ability	Chinese, Japanese, English
Province	Beijing

Name

Xuefeng Duan

Contact Information

duanxf@im.ac.cn

Language ability

Chinese, Japanese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2002-04--2006-03 Medical Doctor: Kyushu University, Japan 1995-09--2000-06 Medical Bachelor: Peking University Health Science Center
Work Experience	2013-10~Present - Chinese Academy of Sciences Institute of Microbiology - Associate Researcher 2011-01~2013-09 - Kyushu University Immunology Research Center - Assistant Professor 2009-04~2010-12 - Kyushu University Medical Institute of Biodefense - Special Assistant 2006-04~2009-03 - Kyushu University Medical Research Institute - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2002-04--2006-03 Medical Doctor: Kyushu University, Japan
1995-09--2000-06 Medical Bachelor: Peking University Health Science Center

Work Experience

2013-10~Present - Chinese Academy of Sciences Institute of Microbiology - Associate Researcher
2011-01~2013-09 - Kyushu University Immunology Research Center - Assistant Professor
2009-04~2010-12 - Kyushu University Medical Institute of Biodefense - Special Assistant
2006-04~2009-03 - Kyushu University Medical Research Institute - Postdoctoral Researcher

Areas of Focus	Infection Immunity Immune Aging Cell Movement
Publications	UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS, 8th Author, 2023 Legionella pneumophila Risk from Cooling Tower Systems in China, 14th Author, 2022 SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG)(11)(B) activity, 12th Author, 2022 Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging, 5th Author, 2021 Influenza virus matrix protein M1 interacts with SLD5 to block host cell cycle, 7th Author, 2019 The virulence of legionella pneumophila is positively correlated with its ability to stimulate nf-b activation, 11th Author, 2018 Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology, 2nd Author, 2018 Natural killer cells are activated and play a protective role against ZIKA virus infection in mice, 1st Author, 2017 The AP-1 transcription factor JunB is required for Th17 cell differentiation, 7th Author, 2017 Bidirectional factors impact the migration of nk cells to draining lymph node in aged mice during influenza virus infection, 1st Author, 2017 Differential immune response of influenza a virus-infected dendritic cells and association with autophagy, 11th Author, 2017 Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus, 5th Author, 2015 NK-cells are involved in thymic atrophy induced by influenza A virus infection, 1st Author, 2015 DOCK5 functions as a key signaling adaptor that links Fc��RI signals to microtubule dynamics during mast cell degranulation, 4th Author, 2014 The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation, 5th Author, 2013 Antiangiogenic Tumor Therapy by DNA Vaccine Inducing Aquaporin-1-Specific CTL Based on Ubiquitin-Proteasome System in Mice, 5th Author, 2012 DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses, 0th Author, 2012 Blockade of Inflammatory Responses by a Small-Molecule Inhibitor of the Rac Activator DOCK2, 3rd Author, 2012 Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells, 7th Author, 2008

Areas of Focus

Infection Immunity
Immune Aging
Cell Movement

Publications

UBL7 enhances antiviral innate immunity by promoting Lys27-linked polyubiquitination of MAVS, 8th Author, 2023
Legionella pneumophila Risk from Cooling Tower Systems in China, 14th Author, 2022
SARS-CoV-2 ORF10 impairs cilia by enhancing CUL2(ZYG)(11)(B) activity, 12th Author, 2022
Declined miR-181a-5p expression is associated with impaired natural killer cell development and function with aging, 5th Author, 2021
Influenza virus matrix protein M1 interacts with SLD5 to block host cell cycle, 7th Author, 2019
The virulence of legionella pneumophila is positively correlated with its ability to stimulate nf-b activation, 11th Author, 2018
Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology, 2nd Author, 2018
Natural killer cells are activated and play a protective role against ZIKA virus infection in mice, 1st Author, 2017
The AP-1 transcription factor JunB is required for Th17 cell differentiation, 7th Author, 2017
Bidirectional factors impact the migration of nk cells to draining lymph node in aged mice during influenza virus infection, 1st Author, 2017
Differential immune response of influenza a virus-infected dendritic cells and association with autophagy, 11th Author, 2017
Intronic regulation of Aire expression by Jmjd6 for self-tolerance induction in the thymus, 5th Author, 2015
NK-cells are involved in thymic atrophy induced by influenza A virus infection, 1st Author, 2015
DOCK5 functions as a key signaling adaptor that links Fc��RI signals to microtubule dynamics during mast cell degranulation, 4th Author, 2014
The Rac activator DOCK2 regulates natural killer cell-mediated cytotoxicity in mice through the lytic synapse formation, 5th Author, 2013
Antiangiogenic Tumor Therapy by DNA Vaccine Inducing Aquaporin-1-Specific CTL Based on Ubiquitin-Proteasome System in Mice, 5th Author, 2012
DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses, 0th Author, 2012
Blockade of Inflammatory Responses by a Small-Molecule Inhibitor of the Rac Activator DOCK2, 3rd Author, 2012
Malaria parasites require TLR9 signaling for immune evasion by activating regulatory T cells, 7th Author, 2008

Infection Immunity Pathogens Immune Response Aging Cellular Senescence Cell Migration Immune Cells Inflammation Disease Mechanisms

Guang-Hui Liu - University of Chinese Academy of Sciences

Jingyi Li - University of Chinese Academy of Sciences

Zhang Zhirong - Southern University of Science and Technology

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