Professor | Weiwei Luo | Asia Growth Partners

Name	Weiwei Luo
Contact Information	wwluo@wh.iov.cn
Language ability	Chinese, English
Province	Hubei

Name

Weiwei Luo

Contact Information

wwluo@wh.iov.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2011-09--2016-06 PhD: Wuhan University 2006-09--2010-06 Bachelor: Wuhan University
Work Experience	2021-01~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher 2020-10~2020-12 - Wuhan Institute of Virology, Chinese Academy of Sciences - Junior Researcher 2018-08~2020-10 - Wuhan Institute of Virology - Associate Researcher 2016-07~2018-07 - Wuhan Institute of Virology - Postdoctoral (Associate Researcher)
Awards	National Natural Science Foundation for Excellent Young Scholars (2020): National Level Youth Innovation Promotion Association of the Chinese Academy of Sciences (2019): Institute Level Outstanding Young Scholar of Hubei Province Cell Biology Society (2019): Provincial Level Wuhan 'Yellow Crane Talent' (2019): Municipal Level Annual Young Person of Wuhan Institute of Virology (2018): Institute Level Academic Innovation Award of Wuhan University (2016): First Prize, Institute Level National Postdoctoral Innovation Talent Support Program (2016): National Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2011-09--2016-06 PhD: Wuhan University
2006-09--2010-06 Bachelor: Wuhan University

Work Experience

2021-01~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher
2020-10~2020-12 - Wuhan Institute of Virology, Chinese Academy of Sciences - Junior Researcher
2018-08~2020-10 - Wuhan Institute of Virology - Associate Researcher
2016-07~2018-07 - Wuhan Institute of Virology - Postdoctoral (Associate Researcher)

Awards

National Natural Science Foundation for Excellent Young Scholars (2020): National Level
Youth Innovation Promotion Association of the Chinese Academy of Sciences (2019): Institute Level
Outstanding Young Scholar of Hubei Province Cell Biology Society (2019): Provincial Level
Wuhan 'Yellow Crane Talent' (2019): Municipal Level
Annual Young Person of Wuhan Institute of Virology (2018): Institute Level
Academic Innovation Award of Wuhan University (2016): First Prize, Institute Level
National Postdoctoral Innovation Talent Support Program (2016): National Level

Areas of Focus	Antiviral innate immunity and inflammation signaling mechanisms Interaction mechanisms between innate immunity and body metabolism and their impact on pathological processes
Publications	Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes, Luo, WeiWei, Tong, Zhen, Cao, Pan, Wang, FuBing, Liu, Ying, Zheng, ZhouQin, Wang, SuYun, Li, Shu, Wang, YanYi, 2022 The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response, Li, Chen, Feng, Lu, Luo, WeiWei, Lei, CaoQi, Li, Mi, Shu, HongBing, 2021 Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response, Zou, HongMei, Huang, ZheFu, Yang, Yan, Luo, WeiWei, Wang, SuYun, Luo, MinHua, Fu, YuZhi, Wang, YanYi, 2020 USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA, HongYan Zhang, BoWei Liao, ZhiSheng Xu, Yong Ran, DongPeng Wang, Yan Yang, WeiWei Luo, YanYi Wang, 2020 Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response, Li, WeiWei, Nie, Ying, Yang, Yan, Ran, Yong, Luo, WeiWei, Xiong, MeiGuang, Wang, SuYun, Xu, ZhiSheng, Wang, YanYi, 2020 YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking, Ran, Yong, Xiong, Meiguang, Xu, Zhisheng, Luo, Weiwei, Wang, Suyun, Wang, YanYi, 2019 The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors, Pan Cao, WeiWei Luo, Chen Li, Zhen Tong, ZhouQin Zheng, Lu Zhou, Yong Xiong, Shu Li, 2019 Delicate regulation of the cGAS–MITA-mediated innate immune response, WeiWei Luo, HongBing Shu, 2018 The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors, Lian, Huan, Zang, Ru, Wei, Jin, Ye, Wen, Hu, MingMing, Chen, YunDa, Zhang, XiaNan, Guo, Yi, Lei, CaoQi, Yang, Qing, Luo, WeiWei, Li, Shu, Shu, HongBing, 2018 ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response, Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, XiaNan Zhang, YunDa Chen, YuZhi Fu, MingMing Hu, CaoQi Lei, WeiWei Luo, Shu Li, HongBing Shu, 2018 TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses, Yang, Qing, Liu, TianTian, Lin, Heng, Zhang, Man, Wei, Jin, Luo, WeiWei, Hu, YunHong, Zhong, Bo, Hu, MingMing, Shu, HongBing, 2017 Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses, Luo, WeiWei, Shu, HongBing, 2017 iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA, Luo, WeiWei, Li, Shu, Li, Chen, Zheng, ZhouQin, Cao, Pan, Tong, Zhen, Lian, Huan, Wang, SuYun, Shu, HongBing, Wang, YanYi, 2017 iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING, Luo, WeiWei, Li, Shu, Li, Chen, Lian, Huan, Yang, Qing, Zhong, Bo, Shu, HongBing, 2016 Kruppel-like factor 4 negatively regulates cellular antiviral immune response, Luo, WeiWei, Lian, Huan, Zhong, Bo, Shu, HongBing, Li, Shu, 2016 The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response, Yang, Yan, Wang, SuYun, Huang, ZheFu, Zou, HongMei, Yan, BingRu, Luo, WeiWei, Wang, YanYi, 2016

Areas of Focus

Antiviral innate immunity and inflammation signaling mechanisms
Interaction mechanisms between innate immunity and body metabolism and their impact on pathological processes

Publications

Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes, Luo, WeiWei, Tong, Zhen, Cao, Pan, Wang, FuBing, Liu, Ying, Zheng, ZhouQin, Wang, SuYun, Li, Shu, Wang, YanYi, 2022
The RNA-binding protein LUC7L2 mediates MITA/STING intron retention to negatively regulate innate antiviral response, Li, Chen, Feng, Lu, Luo, WeiWei, Lei, CaoQi, Li, Mi, Shu, HongBing, 2021
Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response, Zou, HongMei, Huang, ZheFu, Yang, Yan, Luo, WeiWei, Wang, SuYun, Luo, MinHua, Fu, YuZhi, Wang, YanYi, 2020
USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA, HongYan Zhang, BoWei Liao, ZhiSheng Xu, Yong Ran, DongPeng Wang, Yan Yang, WeiWei Luo, YanYi Wang, 2020
Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response, Li, WeiWei, Nie, Ying, Yang, Yan, Ran, Yong, Luo, WeiWei, Xiong, MeiGuang, Wang, SuYun, Xu, ZhiSheng, Wang, YanYi, 2020
YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking, Ran, Yong, Xiong, Meiguang, Xu, Zhisheng, Luo, Weiwei, Wang, Suyun, Wang, YanYi, 2019
The heterogeneous nuclear ribonucleoprotein hnRNPM inhibits RNA virus-triggered innate immunity by antagonizing RNA sensing of RIG-I-like receptors, Pan Cao, WeiWei Luo, Chen Li, Zhen Tong, ZhouQin Zheng, Lu Zhou, Yong Xiong, Shu Li, 2019
Delicate regulation of the cGAS–MITA-mediated innate immune response, WeiWei Luo, HongBing Shu, 2018
The Zinc-Finger Protein ZCCHC3 Binds RNA and Facilitates Viral RNA Sensing and Activation of the RIG-I-like Receptors, Lian, Huan, Zang, Ru, Wei, Jin, Ye, Wen, Hu, MingMing, Chen, YunDa, Zhang, XiaNan, Guo, Yi, Lei, CaoQi, Yang, Qing, Luo, WeiWei, Li, Shu, Shu, HongBing, 2018
ZCCHC3 is a co-sensor of cGAS for dsDNA recognition in innate immune response, Huan Lian, Jin Wei, Ru Zang, Wen Ye, Qing Yang, XiaNan Zhang, YunDa Chen, YuZhi Fu, MingMing Hu, CaoQi Lei, WeiWei Luo, Shu Li, HongBing Shu, 2018
TRIM32-TAX1BP1-dependent selective autophagic degradation of TRIF negatively regulates TLR3/4-mediated innate immune responses, Yang, Qing, Liu, TianTian, Lin, Heng, Zhang, Man, Wei, Jin, Luo, WeiWei, Hu, YunHong, Zhong, Bo, Hu, MingMing, Shu, HongBing, 2017
Emerging roles of rhomboid-like pseudoproteases in inflammatory and innate immune responses, Luo, WeiWei, Shu, HongBing, 2017
iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA, Luo, WeiWei, Li, Shu, Li, Chen, Zheng, ZhouQin, Cao, Pan, Tong, Zhen, Lian, Huan, Wang, SuYun, Shu, HongBing, Wang, YanYi, 2017
iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING, Luo, WeiWei, Li, Shu, Li, Chen, Lian, Huan, Yang, Qing, Zhong, Bo, Shu, HongBing, 2016
Kruppel-like factor 4 negatively regulates cellular antiviral immune response, Luo, WeiWei, Lian, Huan, Zhong, Bo, Shu, HongBing, Li, Shu, 2016
The RNA-binding protein Mex3B is a coreceptor of Toll-like receptor 3 in innate antiviral response, Yang, Yan, Wang, SuYun, Huang, ZheFu, Zou, HongMei, Yan, BingRu, Luo, WeiWei, Wang, YanYi, 2016

Antiviral Innate Immunity Inflammation Signaling Mechanisms Interaction Metabolism Pathological Processes Immune Response Regulation

Lian Huan - Wuhan University

Hongbing Shu - Wuhan University

Wenqing Chen - Wuhan University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us