2007-09--2010-12 PhD: East China University of Science and Technology
2004-09--2007-06 Master's: Zhejiang University of Technology
1997-09--2001-06 Bachelor's: Zhejiang University of Technology
2013-10~2018-06 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
2013-03~2013-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
2011-03~2013-03 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral Researcher
2007-09~2010-12 - East China University of Science and Technology - PhD
2004-09~2007-06 - Zhejiang University of Technology - Master's
1997-09~2001-06 - Zhejiang University of Technology - Bachelor's
Research
Drug Synthesis
Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2, 6th Author, 2024
An improved strategy for identification and annotation of easily in-sourced dissociation diterpene lactones from plant natural products: Taking Andrographis paniculata (Burm. f.) as an example, 11th Author, 2023
Lung CT image enhancement based on total variational frame and wavelet transform, 4th Author, 2022
Information Entropy-Based Strategy for the Quantitative Evaluation of Extensive Hyperspectral Images to Better Unveil Spatial Heterogeneity in Mass Spectrometry Imaging, 10th Author, 2022
Structural Characterization of a Polysaccharide from Gastrodia elata and Its Bioactivity on Gut Microbiota, 2nd Author, 2021
Structural characterization of two novel polysaccharides from Gastrodia elata and their effects on Akkermansia muciniphila, 2nd Author, 2021
A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study, 11th Author, 2021
A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions, 9th Author, 2021
An unexpected reaction of cinobufagin analogues in the presence of PPh3/I-2, 8th Author, 2020
PPh3/I-2-catalyzed one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones, 2nd Author, 2020
A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer’s Disease, 5th Author, 2020
Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin, 5th Author, 2020
Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network-molecular docking-LC-MS E analysis, 11th Author, 2020
Synthesis of oleandrin derivatives and their cytotoxic activity, 7th Author, 2020
Quantitative analysis of fourteen bufadienolides in Venenum Bufonis crude drug and its Chinese patent medicines by ultra-high performance liquid chromatography coupled with tandem mass spectrometry, 6th Author, 2020
Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities, 7th Author, 2019
PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides, 3rd Author, 2019
Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source, 5th Author, 2019
Novel C-17 spirost protostane-type triterpenoids from Alismaplantago-aquatica with anti-inflammatory activity inCaco-2cells, 4th Author, 2019
Novel C-17 spirost protostane-type triterpenoids from Alisma plantago-aquatica with antiinflammatory activity in Caco-2 cells, 4th Author, 2019
A high-efficiency strategy integrating offline two-dimensional separation and data post-processing with dereplication: Characterization of bufadienolides in Venenum Bufonis as a case study, 8th Author, 2019
Four New Depsides Isolated from Salvia miltiorrhiza and Their Significant Nerve-Protective Activities, 5th Author, 2018
A green, efficient and rapid procedure for the hydrogenation of nitroarenes to formanilides in water medium, 1st Author, 2018
A green, efficient, and rapid procedure for the hydrogenation of nitroarenes to formanilides in water, 4th Author, 2018
Compact system for onsite calibration of 1000kV voltage transformers, 3rd Author, 2018
Discovery and structure-activity relationships study of thieno2,3-bpyridine analogues as hepatic gluconeogenesis inhibitors, 4th Author, 2018
Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease, 4th Author, 2018
Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives, 3rd Author, 2017
A l(1) Norm Based Image Prior Combination in Multiframe Superresolution, 1st Author, 2017
Thamnolia vermicularis extract improves learning ability in app/ps1 transgenic mice by ameliorating both a beta and tau pathologies, 3rd Author, 2017
Two new dimmeric xanthanolides isolated from Xanthiurn mogolium Kitag plant, 4th Author, 2017
Two new dimmeric xanthanolides isolated from Xanthium mogolium Kitag plant, 4th Author, 2017
The optimization on transformation from Curdione to Curcumol, 3rd Author, 2017
Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source, 4th Author, 2017
Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies, 3rd Author, 2017
Pd(II)-catalyzed cascade Heck/intramolecular C(sp2)-H amidation reaction: An efficient route to 4-aryl-2-quinolinones, 3rd Author, 2017
A facile and efficient method for the synthesis of N-substituted isoindolin-1-one derivatives under Pd(OAc)2/HCOOH system, 6th Author, 2017
Knockdown of Apolipoprotein E Enhanced Sensitivity of Hep3B Cells to Cardiac Steroids via Regulating Na+/K+-ATPase Signalosome, 6th Author, 2016
Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents, 1st Author, 2016
A facile and efficient method for the synthesis of alkynone by carbonylative Sonogashira coupling using CHCl3 as the CO source, 2nd Author, 2016
Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives, 3rd Author, 2016
Synthesis and decreasing a beta content evaluation of arctigenin-4-yl carbamate derivatives, 3rd Author, 2016
Synthesis and decreasing Ab content evaluation of arctigenin-4-yl carbamate derivatives, 1st Author, 2016
Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives, 2nd Author, 2016
Acetohydrazone: A Transient Directing Group for Arylation of Unactivated C(sp(3))-H Bonds, 2nd Author, 2016
Synthesis of 3,4-disubstituted-furan-2(5H)-one derivatives by Suzuki-Miyaura reaction, 1st Author, 2015
BBT improves glucose homeostasis by ameliorating beta-cell dysfunction in type 2 diabetic mice, 4th Author, 2015
Synthesis and cytotoxicity evaluation of 4-amino-4-dehydroxylarctigenin derivatives in glucose-starved A549 tumor cells, 1st Author, 2015
Catalyst-free synthesis of isoindolin-1-imine derivatives via multi-component reaction in water medium, 3rd Author, 2015
Ullmann-type C-N coupling reaction catalyzed by CuI/metformin, 3rd Author
Keywords
Drug SynthesisPharmaceutical ChemistryTraditional Chinese MedicineNatural ProductsBioactivityPolysaccharidesAlzheimer'S DiseaseCancerInflammationAnalytical Chemistry
Area of Focus
Acupuncture | Endocrinology | Regulation | Alzheimer'S Disease | Cognitive Disorders | Rehabilitation | Research | Traditional Chinese Medicine | Therapy | Neurology
