Areas of Focus
- Drug Synthesis
Work Experience
- 2013-10~2018-06 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Associate Researcher
- 2013-03~2013-10 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Assistant Researcher
- 2011-03~2013-03 - Shanghai Institute of Materia Medica, Chinese Academy of Sciences - Postdoctoral Researcher
- 2007-09~2010-12 - East China University of Science and Technology - PhD
- 2004-09~2007-06 - Zhejiang University of Technology - Master's
- 1997-09~2001-06 - Zhejiang University of Technology - Bachelor's
Academic Background & Achievements
- 2007-09--2010-12 PhD: East China University of Science and Technology
- 2004-09--2007-06 Master's: Zhejiang University of Technology
- 1997-09--2001-06 Bachelor's: Zhejiang University of Technology
Publications
- Design, synthesis and biological evaluation of betulinic acid derivatives as potential inhibitors of 3CL-protease of SARS-CoV-2, 6th Author, 2024
- An improved strategy for identification and annotation of easily in-sourced dissociation diterpene lactones from plant natural products: Taking Andrographis paniculata (Burm. f.) as an example, 11th Author, 2023
- Lung CT image enhancement based on total variational frame and wavelet transform, 4th Author, 2022
- Information Entropy-Based Strategy for the Quantitative Evaluation of Extensive Hyperspectral Images to Better Unveil Spatial Heterogeneity in Mass Spectrometry Imaging, 10th Author, 2022
- Structural Characterization of a Polysaccharide from Gastrodia elata and Its Bioactivity on Gut Microbiota, 2nd Author, 2021
- Structural characterization of two novel polysaccharides from Gastrodia elata and their effects on Akkermansia muciniphila, 2nd Author, 2021
- Restoring perturbed oxylipins with Danqi Tongmai Tablet attenuates acute myocardial infarction, 8th Author, 2021
- A five-dimensional data collection strategy for multicomponent discovery and characterization in Traditional Chinese Medicine: Gastrodia Rhizoma as a case study, 11th Author, 2021
- A new method for the synthesis of chalcone derivatives promoted by PPh3/I(2)under non-alkaline conditions, 9th Author, 2021
- An unexpected reaction of cinobufagin analogues in the presence of PPh3/I-2, 8th Author, 2020
- PPh3/I-2-catalyzed one-pot synthesis of 4,6-diarylpyrimidin-2(1H)-ones, 2nd Author, 2020
- A Network-Based Approach to Explore the Mechanisms of Uncaria Alkaloids in Treating Hypertension and Alleviating Alzheimer’s Disease, 5th Author, 2020
- Design, synthesis and anti-tumor activities of carbamate derivatives of cinobufagin, 5th Author, 2020
- Active constituents and mechanisms of Respiratory Detox Shot, a traditional Chinese medicine prescription, for COVID-19 control and prevention: Network-molecular docking-LC-MS E analysis, 11th Author, 2020
- Synthesis of oleandrin derivatives and their cytotoxic activity, 7th Author, 2020
- Quantitative analysis of fourteen bufadienolides in Venenum Bufonis crude drug and its Chinese patent medicines by ultra-high performance liquid chromatography coupled with tandem mass spectrometry, 6th Author, 2020
- Gastrodia elata Blume Polysaccharides: A Review of Their Acquisition, Analysis, Modification, and Pharmacological Activities, 7th Author, 2019
- PPh3/I-2/HCOOH: An efficient CO source for the synthesis of phthalimides, 3rd Author, 2019
- Palladium-catalyzed carbonylative Sonogashira cross-coupling for the synthesis of alkynones with formic acid as the CO source, 5th Author, 2019
- Novel C-17 spirost protostane-type triterpenoids from Alismaplantago-aquatica with anti-inflammatory activity inCaco-2cells, 4th Author, 2019
- Novel C-17 spirost protostane-type triterpenoids from Alisma plantago-aquatica with antiinflammatory activity in Caco-2 cells, 4th Author, 2019
- A high-efficiency strategy integrating offline two-dimensional separation and data post-processing with dereplication: Characterization of bufadienolides in Venenum Bufonis as a case study, 8th Author, 2019
- Four New Depsides Isolated from Salvia miltiorrhiza and Their Significant Nerve-Protective Activities, 5th Author, 2018
- A green, efficient and rapid procedure for the hydrogenation of nitroarenes to formanilides in water medium, 1st Author, 2018
- A green, efficient, and rapid procedure for the hydrogenation of nitroarenes to formanilides in water, 4th Author, 2018
- Compact system for onsite calibration of 1000kV voltage transformers, 3rd Author, 2018
- Discovery and structure-activity relationships study of thieno2,3-bpyridine analogues as hepatic gluconeogenesis inhibitors, 4th Author, 2018
- Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease, 4th Author, 2018
- Synthesis and glucose-stimulate insulin secretion (GSIS) evaluation of vindoline derivatives, 3rd Author, 2017
- A l(1) Norm Based Image Prior Combination in Multiframe Superresolution, 1st Author, 2017
- Thamnolia vermicularis extract improves learning ability in app/ps1 transgenic mice by ameliorating both a beta and tau pathologies, 3rd Author, 2017
- Two new dimmeric xanthanolides isolated from Xanthiurn mogolium Kitag plant, 4th Author, 2017
- Two new dimmeric xanthanolides isolated from Xanthium mogolium Kitag plant, 4th Author, 2017
- The optimization on transformation from Curdione to Curcumol, 3rd Author, 2017
- Palladium-Catalyzed Formylation of Aryl Iodides with HCOOH as CO Source, 4th Author, 2017
- Thamnolia vermicularis extract improves learning ability in APP/PS1 transgenic mice by ameliorating both Aβ and Tau pathologies, 3rd Author, 2017
- Pd(II)-catalyzed cascade Heck/intramolecular C(sp2)-H amidation reaction: An efficient route to 4-aryl-2-quinolinones, 3rd Author, 2017
- A facile and efficient method for the synthesis of N-substituted isoindolin-1-one derivatives under Pd(OAc)2/HCOOH system, 6th Author, 2017
- Knockdown of Apolipoprotein E Enhanced Sensitivity of Hep3B Cells to Cardiac Steroids via Regulating Na+/K+-ATPase Signalosome, 6th Author, 2016
- Synthesis and biological evaluation of bufalin-3-yl nitrogen-containing-carbamate derivatives as anticancer agents, 1st Author, 2016
- A facile and efficient method for the synthesis of alkynone by carbonylative Sonogashira coupling using CHCl3 as the CO source, 2nd Author, 2016
- Synthesis and decreasing Aβ content evaluation of arctigenin-4-yl carbamate derivatives, 3rd Author, 2016
- Synthesis and decreasing a beta content evaluation of arctigenin-4-yl carbamate derivatives, 3rd Author, 2016
- Synthesis and decreasing Ab content evaluation of arctigenin-4-yl carbamate derivatives, 1st Author, 2016
- Synthesis and cytotoxicity evaluation of 4 '-amino-4 '-dehydroxyloleandrin derivatives, 2nd Author, 2016
- Acetohydrazone: A Transient Directing Group for Arylation of Unactivated C(sp(3))-H Bonds, 2nd Author, 2016
- Synthesis of 3,4-disubstituted-furan-2(5H)-one derivatives by Suzuki-Miyaura reaction, 1st Author, 2015
- BBT improves glucose homeostasis by ameliorating beta-cell dysfunction in type 2 diabetic mice, 4th Author, 2015
- Synthesis and cytotoxicity evaluation of 4-amino-4-dehydroxylarctigenin derivatives in glucose-starved A549 tumor cells, 1st Author, 2015
- Catalyst-free synthesis of isoindolin-1-imine derivatives via multi-component reaction in water medium, 3rd Author, 2015
- Ullmann-type C-N coupling reaction catalyzed by CuI/metformin, 3rd Author
