Professor | Hongxing Lei | Asia Growth Partners

Name	Hongxing Lei
Contact Information	LEIHX@BIG.AC.CN
Language ability	English, Chinese
Province	Beijing

Name

Hongxing Lei

Contact Information

LEIHX@BIG.AC.CN

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	1998-08--2003-05 Ph.D. in Biochemistry: Kansas State University 1987-09--1991-06 Bachelor's in Engineering: Huazhong University of Science and Technology
Work Experience	2003-08~2008-06 - University of Delaware/University of California, Davis - Postdoctoral/Research Group Leader 1991-07~1998-06 - Academy of Military Medical Sciences - Assistant Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

1998-08--2003-05 Ph.D. in Biochemistry: Kansas State University
1987-09--1991-06 Bachelor's in Engineering: Huazhong University of Science and Technology

Work Experience

2003-08~2008-06 - University of Delaware/University of California, Davis - Postdoctoral/Research Group Leader
1991-07~1998-06 - Academy of Military Medical Sciences - Assistant Researcher

Areas of Focus	Systems Biology Alzheimer's Disease Stem Cells Big Data
Publications	A two-gene marker for the two-tiered innate immune response in COVID-19 patients, Hongxing Lei, 2022 Single-cell RNA-Seq revealed profound immune alteration in the peripheral blood of patients with bacterial infection, Lei, Hongxing, Wang, Chi, Wang, Yunlai, Wang, Chengbin, 2021 A host-based two-gene model for the identification of bacterial infection in general clinical settings, Lei, Hongxing, Xu, Xiaoyue, Wang, Chi, Xue, Dandan, Wang, Chengbin, Chen, Jiankui, 2021 A single transcript for the prognosis of disease severity in COVID-19 patients, Hongxing Lei, 2021 Big Data and the Brain: Peeking at the Future, Hongzhu Qu, Hongxing Lei, Xiangdong Fang, 2019 Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders, Xing Peng, Zhengshan Zhang, Dongqing Ye, Peiqi Xing, Zhengxing Zou, Hongxing Lei, Lian Duan, 2019 Evaluation of Peripheral Immune Dysregulation in Alzheimer's Disease and Vascular Dementia, Guo, Zongjun, Peng, Xing, Li, HuiYun, Wang, Yunlai, Qian, Ying, Wang, Zhihong, Ye, Dongqing, Ji, Xiaoyun, Wang, Zhixin, Wang, Yanjiang, Chen, Dongwan, Lei, Hongxing, 2019 GSA: Genome Sequence Archive, Wang, Yanqing, Song, Fuhai, Zhu, Junwei, Zhang, Sisi, Yang, Yadong, Chen, Tingting, Tang, Bixia, Dong, Lili, Ding, Nan, Zhang, Qian, Bai, Zhouxian, Dong, Xunong, Chen, Huanxin, Sun, Mingyuan, Zhai, Shuang, Sun, Yubin, Yu, Lei, Lan, Li, Xiao, Jingfa, Fang, Xiangdong, Lei, Hongxing, Zhang, Zhang, Zhao, Wenming, 2017 The frontline of immune response in peripheral blood, Song, Fuhai, Qian, Ying, Peng, Xing, Li, Xiuhui, Xing, Peiqi, Ye, Dongqing, Lei, Hongxing, 2017 Perturbation of the transcriptome: implications of the innate immune system in Alzheimer's disease, Song, Fuhai, Qian, Ying, Peng, Xing, Han, Guangchun, Wang, Jiajia, Bai, Zhouxian, Crack, Peter J, Lei, Hongxing, 2016 AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease, Bai, Zhouxian, Han, Guangchun, Xie, Bin, Wang, Jiajia, Song, Fuhai, Peng, Xing, Lei, Hongxing, 2016 Alzheimer's Disease: Genomics and Beyond, Song, Fuhai, Han, Guangchun, Bai, Zhouxian, Peng, Xing, Wang, Jiajia, Lei, Hongxing, Hurley, MJ, 2015 Chromosome 19p in Alzheimer's Disease: When Genome Meets Transcriptome, Wang, Jiajia, Feng, Xuemei, Bai, Zhouxian, Jin, LeeWay, Duan, Yong, Lei, Hongxing, 2014 Conformational Elasticity can Facilitate TALE DNA Recognition, Lei, Hongxing, Sun, Jiya, Baldwin, Enoch P, Segal, David J, Duan, Yong, Donev, R, 2014 Hidden Risk Genes with High-Order Intragenic Epistasis in Alzheimer's Disease, Sun, Jiya, Song, Fuhai, Wang, Jiajia, Han, Guangchun, Bai, Zhouxian, Xie, Bin, Feng, Xuemei, Jia, Jianping, Duan, Yong, Lei, Hongxing, 2014 Characteristic Transformation of Blood Transcriptome in Alzheimer's Disease, Han, Guangchun, Wang, Jiajia, Zeng, Fan, Feng, Xuemei, Yu, Jun, Cao, HongYuan, Yi, Xu, Zhou, Huadong, Jin, LeeWay, Duan, Yong, Wang, YanJiang, Lei, Hongxing, 2013 The functional network of human divergently paired genes (DPGs), Lei Hongxing, 2013 iBIG: An Integrative Network Tool for Supporting Human Disease Mechanism Studies, Sun Jiya, Pan Yuyun, Feng Xuemei, Zhang Huijuan, Duan Yong, Lei Hongxing, 2013 Concerted Perturbation Observed in a Hub Network in Alzheimer's Disease, Liang, Dapeng, Han, Guangchun, Feng, Xuemei, Sun, Jiya, Duan, Yong, Lei, Hongxing, 2012 Down-Regulation of Energy Metabolism in Alzheimer's Disease is a Protective Response of Neurons to the Microenvironment, Sun, Jiya, Feng, Xuemei, Liang, Dapeng, Duan, Yong, Lei, Hongxing, 2012

Areas of Focus

Systems Biology
Alzheimer's Disease
Stem Cells
Big Data

Publications

A two-gene marker for the two-tiered innate immune response in COVID-19 patients, Hongxing Lei, 2022
Single-cell RNA-Seq revealed profound immune alteration in the peripheral blood of patients with bacterial infection, Lei, Hongxing, Wang, Chi, Wang, Yunlai, Wang, Chengbin, 2021
A host-based two-gene model for the identification of bacterial infection in general clinical settings, Lei, Hongxing, Xu, Xiaoyue, Wang, Chi, Xue, Dandan, Wang, Chengbin, Chen, Jiankui, 2021
A single transcript for the prognosis of disease severity in COVID-19 patients, Hongxing Lei, 2021
Big Data and the Brain: Peeking at the Future, Hongzhu Qu, Hongxing Lei, Xiangdong Fang, 2019
Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders, Xing Peng, Zhengshan Zhang, Dongqing Ye, Peiqi Xing, Zhengxing Zou, Hongxing Lei, Lian Duan, 2019
Evaluation of Peripheral Immune Dysregulation in Alzheimer's Disease and Vascular Dementia, Guo, Zongjun, Peng, Xing, Li, HuiYun, Wang, Yunlai, Qian, Ying, Wang, Zhihong, Ye, Dongqing, Ji, Xiaoyun, Wang, Zhixin, Wang, Yanjiang, Chen, Dongwan, Lei, Hongxing, 2019
GSA: Genome Sequence Archive, Wang, Yanqing, Song, Fuhai, Zhu, Junwei, Zhang, Sisi, Yang, Yadong, Chen, Tingting, Tang, Bixia, Dong, Lili, Ding, Nan, Zhang, Qian, Bai, Zhouxian, Dong, Xunong, Chen, Huanxin, Sun, Mingyuan, Zhai, Shuang, Sun, Yubin, Yu, Lei, Lan, Li, Xiao, Jingfa, Fang, Xiangdong, Lei, Hongxing, Zhang, Zhang, Zhao, Wenming, 2017
The frontline of immune response in peripheral blood, Song, Fuhai, Qian, Ying, Peng, Xing, Li, Xiuhui, Xing, Peiqi, Ye, Dongqing, Lei, Hongxing, 2017
Perturbation of the transcriptome: implications of the innate immune system in Alzheimer's disease, Song, Fuhai, Qian, Ying, Peng, Xing, Han, Guangchun, Wang, Jiajia, Bai, Zhouxian, Crack, Peter J, Lei, Hongxing, 2016
AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease, Bai, Zhouxian, Han, Guangchun, Xie, Bin, Wang, Jiajia, Song, Fuhai, Peng, Xing, Lei, Hongxing, 2016
Alzheimer's Disease: Genomics and Beyond, Song, Fuhai, Han, Guangchun, Bai, Zhouxian, Peng, Xing, Wang, Jiajia, Lei, Hongxing, Hurley, MJ, 2015
Chromosome 19p in Alzheimer's Disease: When Genome Meets Transcriptome, Wang, Jiajia, Feng, Xuemei, Bai, Zhouxian, Jin, LeeWay, Duan, Yong, Lei, Hongxing, 2014
Conformational Elasticity can Facilitate TALE DNA Recognition, Lei, Hongxing, Sun, Jiya, Baldwin, Enoch P, Segal, David J, Duan, Yong, Donev, R, 2014
Hidden Risk Genes with High-Order Intragenic Epistasis in Alzheimer's Disease, Sun, Jiya, Song, Fuhai, Wang, Jiajia, Han, Guangchun, Bai, Zhouxian, Xie, Bin, Feng, Xuemei, Jia, Jianping, Duan, Yong, Lei, Hongxing, 2014
Characteristic Transformation of Blood Transcriptome in Alzheimer's Disease, Han, Guangchun, Wang, Jiajia, Zeng, Fan, Feng, Xuemei, Yu, Jun, Cao, HongYuan, Yi, Xu, Zhou, Huadong, Jin, LeeWay, Duan, Yong, Wang, YanJiang, Lei, Hongxing, 2013
The functional network of human divergently paired genes (DPGs), Lei Hongxing, 2013
iBIG: An Integrative Network Tool for Supporting Human Disease Mechanism Studies, Sun Jiya, Pan Yuyun, Feng Xuemei, Zhang Huijuan, Duan Yong, Lei Hongxing, 2013
Concerted Perturbation Observed in a Hub Network in Alzheimer's Disease, Liang, Dapeng, Han, Guangchun, Feng, Xuemei, Sun, Jiya, Duan, Yong, Lei, Hongxing, 2012
Down-Regulation of Energy Metabolism in Alzheimer's Disease is a Protective Response of Neurons to the Microenvironment, Sun, Jiya, Feng, Xuemei, Liang, Dapeng, Duan, Yong, Lei, Hongxing, 2012

Systems Biology: Computational Biology Network Analysis Gene Regulation Protein Interaction Metabolic Pathways Cellular Processes Bioinformatics Modeling Simulation Data Integration Alzheimer'S Disease: Neurodegeneration Amyloid Plaques Tau Protein Cognitive Decline Biomarkers Genetic Factors Therapeutic Targets Brain Imaging Clinical Trials Disease Progression Stem Cells: Pluripotency Differentiation Regenerative Medicine Cell Therapy Tissue Engineering Embryonic Stem Cells Adult Stem Cells Induced Pluripotent Stem Cells Stem Cell Niche Transplantation Big Data: Data Mining Machine Learning Data Analytics High-Throughput Sequencing Data Visualization Large-Scale Datasets Computational Tools Data Storage Data Sharing

Huang Jie - Southern University of Science and Technology

Huan Ren - Southern University of Science and Technology

Shenying Fang - Southern University of Science and Technology

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