雷红星
Medical School
中国科学院大学
北京
Language: 英语, 中文
Contact
系统生物学: 计算生物学 网络分析 基因调控 蛋白质相互作用 代谢途径 细胞过程 生物信息学 建模 模拟 数据整合 阿尔茨海默症: 神经退行性疾病 淀粉样斑块 Tau蛋白 认知衰退 生物标志物 遗传因素 治疗靶点 脑成像 临床试验 疾病进展 干细胞: 多能性 分化 再生医学 细胞治疗 组织工程 胚胎干细胞 成人干细胞 诱导多能干细胞 干细胞微环境 移植 大数据: 数据挖掘 机器学习 数据分析 高通量测序 数据可视化 大规模数据集 计算工具 数据存储 数据共享
Areas of Focus
  • 系统生物学
  • 阿尔茨海默症
  • 干细胞
  • 大数据
Work Experience
  • 2003-08~2008-06 - 美国德拉华大学/加州大学戴维斯分校 - 博士后/研究组主管
  • 1991-07~1998-06 - 军事医学科学院 - 助理研究员
Academic Background & Achievements
  • 1998-08--2003-05 生物化学博士: 堪萨斯州立大学
  • 1987-09--1991-06 工学学士: 华中理工大学
Publications
  • A two-gene marker for the two-tiered innate immune response in COVID-19 patients, Hongxing Lei, 2022
  • Single-cell RNA-Seq revealed profound immune alteration in the peripheral blood of patients with bacterial infection, Lei, Hongxing, Wang, Chi, Wang, Yunlai, Wang, Chengbin, 2021
  • A host-based two-gene model for the identification of bacterial infection in general clinical settings, Lei, Hongxing, Xu, Xiaoyue, Wang, Chi, Xue, Dandan, Wang, Chengbin, Chen, Jiankui, 2021
  • A single transcript for the prognosis of disease severity in COVID-19 patients, Hongxing Lei, 2021
  • Big Data and the Brain: Peeking at the Future, Hongzhu Qu, Hongxing Lei, Xiangdong Fang, 2019
  • Gene dysregulation in peripheral blood of moyamoya disease and comparison with other vascular disorders, Xing Peng, Zhengshan Zhang, Dongqing Ye, Peiqi Xing, Zhengxing Zou, Hongxing Lei, Lian Duan, 2019
  • Evaluation of Peripheral Immune Dysregulation in Alzheimer's Disease and Vascular Dementia, Guo, Zongjun, Peng, Xing, Li, HuiYun, Wang, Yunlai, Qian, Ying, Wang, Zhihong, Ye, Dongqing, Ji, Xiaoyun, Wang, Zhixin, Wang, Yanjiang, Chen, Dongwan, Lei, Hongxing, 2019
  • GSA: Genome Sequence Archive, Wang, Yanqing, Song, Fuhai, Zhu, Junwei, Zhang, Sisi, Yang, Yadong, Chen, Tingting, Tang, Bixia, Dong, Lili, Ding, Nan, Zhang, Qian, Bai, Zhouxian, Dong, Xunong, Chen, Huanxin, Sun, Mingyuan, Zhai, Shuang, Sun, Yubin, Yu, Lei, Lan, Li, Xiao, Jingfa, Fang, Xiangdong, Lei, Hongxing, Zhang, Zhang, Zhao, Wenming, 2017
  • The frontline of immune response in peripheral blood, Song, Fuhai, Qian, Ying, Peng, Xing, Li, Xiuhui, Xing, Peiqi, Ye, Dongqing, Lei, Hongxing, 2017
  • Perturbation of the transcriptome: implications of the innate immune system in Alzheimer's disease, Song, Fuhai, Qian, Ying, Peng, Xing, Han, Guangchun, Wang, Jiajia, Bai, Zhouxian, Crack, Peter J, Lei, Hongxing, 2016
  • AlzBase: an Integrative Database for Gene Dysregulation in Alzheimer's Disease, Bai, Zhouxian, Han, Guangchun, Xie, Bin, Wang, Jiajia, Song, Fuhai, Peng, Xing, Lei, Hongxing, 2016
  • Alzheimer's Disease: Genomics and Beyond, Song, Fuhai, Han, Guangchun, Bai, Zhouxian, Peng, Xing, Wang, Jiajia, Lei, Hongxing, Hurley, MJ, 2015
  • Chromosome 19p in Alzheimer's Disease: When Genome Meets Transcriptome, Wang, Jiajia, Feng, Xuemei, Bai, Zhouxian, Jin, LeeWay, Duan, Yong, Lei, Hongxing, 2014
  • Conformational Elasticity can Facilitate TALE DNA Recognition, Lei, Hongxing, Sun, Jiya, Baldwin, Enoch P, Segal, David J, Duan, Yong, Donev, R, 2014
  • Hidden Risk Genes with High-Order Intragenic Epistasis in Alzheimer's Disease, Sun, Jiya, Song, Fuhai, Wang, Jiaj
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