2009-05--2010-04 Visiting Student: University of Illinois at Chicago
2005-09--2011-01 PhD: Kunming Institute of Botany, Chinese Academy of Sciences
2001-09--2005-07 Bachelor's Degree: Sun Yat-sen University
2024-02~Present - Kunming Institute of Botany, Chinese Academy of Sciences - Researcher (Group Leader)
2020-07~2024-02 - Kunming Institute of Botany, Chinese Academy of Sciences - Associate Researcher (Group Leader)
2019-01~2020-06 - Kunming Institute of Zoology, Chinese Academy of Sciences - Associate Researcher
2016-03~2017-03 - Baylor College of Medicine - Postdoctoral Researcher
2013-11~2018-12 - Kunming Institute of Zoology, Chinese Academy of Sciences - Assistant Researcher
2011-05~2013-10 - Yunnan Biovalley Pharmaceutical Co., Ltd. and Kunming Institute of Botany, Chinese Academy of Sciences - Jointly Trained Postdoctoral Researcher
Research
Structure and function of membrane proteins (ion channels) and their research in natural drugs
Analgesic Buxus alkaloids with enhanced selectivity for the low voltage-gated calcium channel Cav3.2 over Cav3.1 through a new binding mode., Nian Yin, 2024
Abietane derived diterpenoids as Cav3.1 antagonists from Salvia digitaloides, Nian Yin, 2023
Caged polycyclic polyprenylated acylphloroglucinols as Ca(v)3.2 low voltage-gated Ca2+ channel inhibitors from Hypericum curvisepalum, Nian Yin, 2022
Icetexane diterpenoids as Cav3.2 T-type calcium channel inhibitors from Salvia prattii and analgesic effect of their Semi-synthesized derivatives, Nian Yin, 2022
Cyclovirobuxine D, a cardiovascular drug from traditional Chinese medicine, alleviates inflammatory and neuropathic pain mainly via inhibition of voltage-gated Ca(v)3.2 channels, Nian Yin, 2022
Discovery of novel coffee diterpenoids with inhibitions on Cav3.1 low voltage-gated Ca2+ channel, Nian Yin, 2022
Icetexane Diterpenoids as Cav3.2 T-type calcium channel inhibitors from Salvia prattii and Analgesic Effect of Their Semi-synthesized Derivatives, Nian Yin, 2022
New ent-kaurane diterpenes from the roasted arabica coffee beans and molecular docking to alpha-glucosidase, Nian Yin, 2021
Scholarinine A, a N3 type caged-monoterpene indole alkaloid as Cav3.1 T-type calcium channel inhibitor from Alstonia scholaris, Nian Yin, 2020
Structure and mechanism of human diacylglycerol O-acyltransferase 1, Nian Yin, 2020
Congenetic Hybrids Derived from Dearomatized Isoprenylated Acylphloroglucinol with Opposite Effects on Ca(v)3.1 Low Voltage Gated Ca2+ Channel, Nian Yin, 2020
Novel Meroterpenoids from Hypericum patulum: Highly Potent Late Na(v)1.5 Sodium Current Inhibitors, Nian Yin, 2020
Hyphenone A, the first 3,3-diisoprenylated bicyclic polyprenylated acylphloroglucinols as Cav3.1 T-type calcium channel inhibitor from Hypericum henryi, Nian Yin, 2019
Salpratlactones A and B: A Pair of cis-trans Tautomeric Abietanes as Ca(v)3.1 T-Type Calcium Channel Agonists from Salvia prattii, Nian Yin, 2019
Two Diterpenoids with Two Skeletons from Euphorbia peplus., Nian Yin, 2018
Valepotriates From the Roots and Rhizomes of Valeriana jatamansi Jones as Novel N-Type Calcium Channel Antagonists, Nian Yin, 2018
Antiacetylcholinesterase triterpenes from the fruits of Cimicifuga yunnanensis, Nian Yin, 2018
Structure of an EIIC sugar transporter trapped in an inward-facing conformation, Nian Yin, 2018
A novel cycloartane triterpenoid from Cimicifuga induces apoptotic and autophagic cell death in human colon cancer HT-29 cells, Nian Yin, 2017
Ca(v)2.2 and Ca(v)3.1 calcium channel inhibitors from Valeriana jatamansi Jones, Nian Yin, 2017
Cimifrigines A-G, cytotoxic triterpenes with an oxime group from the flowers of Cimicifuga frigida, Nian Yin, 2017
Cimifrigines A-G, Cytotoxic Triterpenes with an Oxime Group from the Flowers of Cimicifuga frigid., Nian Yin, 2017
Six new physalins from Physalis alkekengi var. franchetii and their cytotoxicity and antibacterial activity, Nian Yin, 2016
Cytotoxic 9,19-cycloartane triterpenoids from the roots of Cimicifuga foetida L., Nian Yin, 2016
KHF16 is a Leading Structure from Cimicifuga foetida that Suppresses Breast Cancer Partially by Inhibiting the NF-kappa B Signaling Pathway, Nian Yin, 2016
New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment, Nian Yin, 2016
New cycloartane triterpenes from the aerial parts of Cimicifuga heracleifolia, Nian Yin, 2015
New Anti-angiogenic Leading Structure Discovered in the Fruit of Cimicifuga yunnanensis, Nian Yin, 2015
Four New Cucurbitacins from the Fruit of Momordica charantia, Nian Yin, 2014
Cytotoxic 9,19-cycloartane triterpenes from the aerial parts of Cimicifuga yunnanensis, Nian Yin, 2014
New 9, 19-cycloartane triterpenoid from the root of Cimicifuga foetida, Nian Yin, 2014
姜酮的NMR解析, Nian Yin, 2013
Cytotoxic Cycloartane Triterpenes of the TraditionalChinese Medicine 'Shengma' (Cimicifuga dahurica), Nian Yin, 2013
Triterpenes from the Aerial Parts of Cimicifuga yunnanensis and Their Antiproliferative Effects on p53(N236S) Mouse Embryonic Fibroblasts, Nian Yin, 2013
Studies on the Constituents of Cimicifuga foetida Collected in Guizhou Province and Their Cytotoxic Activities, Nian Yin, 2012
A cytotoxic 4 alpha-methyl steroid from the aerial parts of Cimicifuga foetida L, Nian Yin, 2012
Four New 9,19-Cyclolanostane Triterpenes from the Rhizomes of Cimicifuga foetida Collected in Yulong, Nian Yin, 2012
Cycloartane Triterpenoids from Cimicifuga yunnanensis induce Apoptosis of Breast Cancer Cells (MCF7) via p53-dependent Mitochondrial Signaling Pathway, Nian Yin, 2011
Three New Cycloartane (= 9,19-Cyclolanostane) Glycosides from Cimicifuga foetida, Nian Yin, 2011
Five New Triterpene Bisglycosides with Acyclic Side Chains from the Rhizomes of Cimicifuga foetida L., Nian Yin, 2010
Trinor-cycloartane Glycosides from the Rhizomes of Cimicifuga foetida, Nian Yin, 2009
New triterpene diglycosides from the rhizome of Cimifuga foetida, Nian Yin, 2008
Cytotoxic Cycloartane Triterpenes of Traditional Chinese Medicine 'Shengma' (Cimicifugadahurica), Nian Yin, 2008
