Areas of Focus
- Molecular and Signal Transduction Mechanisms of Innate Immune Recognition and Response
- Mechanisms of Innate Immune Response to Viral Infections
- Inflammatory Response and Its Regulatory Mechanisms
- Development of Immune Cells and Organs
Work Experience
- 2016-present - Shanghai Pasteur Institute, Chinese Academy of Sciences - Researcher, Director
- 2012-2016 - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher, Deputy Director
- 2009-2012 - Key Laboratory of Infection and Immunity, Chinese Academy of Sciences - Director
- 2007-present - National International Joint Research Center, Ministry of Science and Technology - Director
- 2006-2009 - National Key Laboratory of Biomacromolecules - Deputy Director
- 2005-2012 - Center for Infection and Immunity, Institute of Biophysics, Chinese Academy of Sciences - Researcher, Director
- 2001-2005 - Center for Molecular Immunology, Institute of Microbiology, Chinese Academy of Sciences - Researcher, Director
- 2000 - Dupont Pharmaceutical Co - Senior Scientist
- 1996-1999 - Massachusetts Institute of Technology - Postdoctoral Researcher
Academic Background & Achievements
- 1991-01--1996-05 PhD: Rutgers University-New Jersey State University
- 1988-09--1990-12 Master's: Institute of Microbiology, Chinese Academy of Sciences
- 1984-09--1988-07 Bachelor's: Nanjing University
Publications
- Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila, Hong Tang, 2019
- NKG2A is a NK cell exhaustion checkpoint for HCV persistence, Hong Tang, 2019
- B Cells Are the Dominant Antigen-Presenting Cells that Activate Naive CD4+ T Cells upon Immunization with a Virus-Derived Nanoparticle Antigen, Hong Tang, 2018
- Bap180/Baf180 is required to maintain homeostasis of intestinal innate immune response in Drosophila and mice, Hong Tang, 2017
- Macrophage-derived IL-1a promotes sterile inflammation in a mouse model of acetaminophen hepatotoxicity, Hong Tang, 2017
- Quinolinate Phosphoribosyltransferase is an Antiviral Host Factor Against Hepatitis C Virus Infection, Hong Tang, 2017
- Aberrant coagulation causesa hyper-inflammatory response in severe influenza pneumonia, Hong Tang, 2016
- Persistent hepatitis C virus infections and hepatopathological manifestations in immune-competent humanized mice, Hong Tang, 2014
- Altered protein prenylation in Sertoli cells is associated with adult infertility resulting from childhood mumps infection, Hong Tang, 2013
- Sequential reassortments underlie diverse influenza H7N9 genotypes in China, Hong Tang, 2013
- Myotubularin-related protein 4 (MTMR4) attenuates BMP/Dpp signaling by dephosphorylation of Smad proteins, Hong Tang, 2013
- PLP2 of Mouse Hepatitis Virus A59 (MHV-A59) Targets TBK1 to Negatively Regulate Cellular Type I Interferon Signaling Pathway, Hong Tang, 2011
- TANK-Binding Kinase 1 Attenuates PTAP-Dependent Retroviral Budding through Targeting Endosomal Sorting Complex Required for Transport-I, Hong Tang, 2011
- MTMR4 Attenuates Transforming Growth Factor β (TGFβ) Signaling by Dephosphorylating R-Smads in Endosomes, Hong Tang, 2010
- Do adaptive immune cells suppress or activate innate immunity, Hong Tang, 2009
- Troglitazone inhibits cell proliferation by attenuation of epidermal growth factor receptor signaling independent of peroxisome proliferator-activated receptor gamma, Hong Tang, 2009
- Hyper innate responses in neonates lead to increased morbidity and mortality after infection., Hong Tang, 2008
- PLP2, a potent deubiquitinase from murine hepatitis virus, strongly inhibits cellular type I interferon production, Hong Tang, 2008
- Adaptive immune cells temper initial innate responses, Hong Tang, 2007
Awards
- Beijing Science and Technology Award, First Prize, Provincial, 2012
- Fourth China Overseas Chinese Contribution Award (Innovation Team), First Prize, National, 2012
- New Century Talents Project, National, 2009
- Second Tan Jiazhen Life Science Innovation Award, Other, 2009
- Jiangsu High-level Entrepreneurial and Innovative Talent Introduction Plan, Provincial, 2009
