Areas of Focus
- Regenerative Medicine
- Stem Cells and Brain Injury Repair
- Neuroregeneration
Work Experience
- 2014-09~Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
- 2014-01~2014-08 - Johns Hopkins University School of Medicine - Research Associate
- 2011-03~2013-12 - Louisiana State University School of Medicine - Postdoctoral Fellow
- 2008-08~2011-02 - University of New Mexico School of Medicine - Postdoctoral Fellow
- 2005-09~2008-03 - College of Agronomy and Biotechnology, China Agricultural University - Postdoctoral Fellow
Academic Background & Achievements
- 2002-09--2005-07 PhD: Institute of Zoology, Chinese Academy of Sciences
- 1999-09--2002-07 MSc: College of Life Sciences, Shandong Normal University
Publications
- Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury, 6th Author, 2023
- Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, 12th Author, Corresponding Author, 2023
- Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain, 10th Author, 2023
- ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-& beta; signaling pathway, 11th Author, Corresponding Author, 2023
- Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice, 10th Author, Corresponding Author, 2023
- The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury, 11th Author, Corresponding Author, 2023
- Mouse model of voluntary movement deficits induced by needlestick injuries to the primary motor cortex, 3rd Author, Corresponding Author, 2022
- Decoding the temporal and regional specification of microglia in the developing human brain, 15th Author, 2022
- Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 9th Author, Corresponding Author, 2022
- Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 8th Author, Corresponding Author, 2022
- Microglial EED is required for synapse engulfment, 14th Author, Corresponding Author, 2022
- Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury, 5th Author, Corresponding Author, 2022
- A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022
- KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs, 7th Author, Corresponding Author, 2022
- Loss of microglial EED impairs synapse density, learning, and memory, 14th Author, Corresponding Author, 2022
- Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development, 5th Author, Corresponding Author, 2022
- A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022
- Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury (vol 11, 1348, 2022), 5th Author, Corresponding Author, 2022
- miR-26a promotes axon regeneration in the mammalian central nervous system by suppressing PTEN expression, 5th Author, 2021
- Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration, 10th Author, Corresponding Author, 2021
- TREM2, microglia, and Alzheimer’s disease, 2nd Author, 2021
- Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters, 8th Author, Corresponding Author, 2021
- Strategies to Promote Long-Distance Optic Nerve Regeneration, 4th Author, 2020
- Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury, 7th Author, 2020
- Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2, 10th Author, Corresponding Author, 2020
- Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2020
- UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters, 7th Author, Corresponding Author, 2020
- SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury, 8th Author, Corresponding Author, 2020
- Prostaglandin E1 Inhibits GLI2 Amplification-Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth, 5th Author, 2020
- GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, 9th Author, 2019
- A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease, 4th Author, 2019
- Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus, 7th Author, 2019
- GA-binding protein GABP beta 1 is required for the proliferation of neural stem/progenitor cells, 9th Author, Corresponding Author, 2019
- Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome, 7th Author, 2019
- Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2019
- MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice, 11th Author, Corresponding Author, 2019
- Commentary: Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus., 3rd Author, Corresponding Author, 2018
- A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs, 7th Author, 2018
- miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds, 7th Author, 2018
- Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration., 10th Author, 2018
- Partial loss of psychiatric risk gene miR-137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, 30th Author, Corresponding Author, 2018
- Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System, 3rd Author, 2018
- MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells, 7th Author, Corresponding Author, 2017
- The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice., 12th Author, Corresponding Author, 2017
- Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury, 2nd Author, 2016
