Professor | Zhaoqian Teng | Asia Growth Partners

Name	Zhaoqian Teng
Contact Information	tengzq@ioz.ac.cn
Language ability	Chinese, English
Province	Beijing

Name

Zhaoqian Teng

Contact Information

tengzq@ioz.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2002-09--2005-07 PhD: Institute of Zoology, Chinese Academy of Sciences 1999-09--2002-07 MSc: College of Life Sciences, Shandong Normal University
Work Experience	2014-09~Present - Institute of Zoology, Chinese Academy of Sciences - Researcher 2014-01~2014-08 - Johns Hopkins University School of Medicine - Research Associate 2011-03~2013-12 - Louisiana State University School of Medicine - Postdoctoral Fellow 2008-08~2011-02 - University of New Mexico School of Medicine - Postdoctoral Fellow 2005-09~2008-03 - College of Agronomy and Biotechnology, China Agricultural University - Postdoctoral Fellow

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2002-09--2005-07 PhD: Institute of Zoology, Chinese Academy of Sciences
1999-09--2002-07 MSc: College of Life Sciences, Shandong Normal University

Work Experience

2014-09~Present - Institute of Zoology, Chinese Academy of Sciences - Researcher
2014-01~2014-08 - Johns Hopkins University School of Medicine - Research Associate
2011-03~2013-12 - Louisiana State University School of Medicine - Postdoctoral Fellow
2008-08~2011-02 - University of New Mexico School of Medicine - Postdoctoral Fellow
2005-09~2008-03 - College of Agronomy and Biotechnology, China Agricultural University - Postdoctoral Fellow

Areas of Focus	Regenerative Medicine Stem Cells and Brain Injury Repair Neuroregeneration
Publications	Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury, 6th Author, 2023 Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, 12th Author, Corresponding Author, 2023 Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain, 10th Author, 2023 ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-& beta; signaling pathway, 11th Author, Corresponding Author, 2023 Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice, 10th Author, Corresponding Author, 2023 The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury, 11th Author, Corresponding Author, 2023 Mouse model of voluntary movement deficits induced by needlestick injuries to the primary motor cortex, 3rd Author, Corresponding Author, 2022 Decoding the temporal and regional specification of microglia in the developing human brain, 15th Author, 2022 Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 9th Author, Corresponding Author, 2022 Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 8th Author, Corresponding Author, 2022 Microglial EED is required for synapse engulfment, 14th Author, Corresponding Author, 2022 Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury, 5th Author, Corresponding Author, 2022 A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022 KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs, 7th Author, Corresponding Author, 2022 Loss of microglial EED impairs synapse density, learning, and memory, 14th Author, Corresponding Author, 2022 Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development, 5th Author, Corresponding Author, 2022 A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022 Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury (vol 11, 1348, 2022), 5th Author, Corresponding Author, 2022 miR-26a promotes axon regeneration in the mammalian central nervous system by suppressing PTEN expression, 5th Author, 2021 Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration, 10th Author, Corresponding Author, 2021 TREM2, microglia, and Alzheimer’s disease, 2nd Author, 2021 Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters, 8th Author, Corresponding Author, 2021 Strategies to Promote Long-Distance Optic Nerve Regeneration, 4th Author, 2020 Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury, 7th Author, 2020 Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2, 10th Author, Corresponding Author, 2020 Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2020 UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters, 7th Author, Corresponding Author, 2020 SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury, 8th Author, Corresponding Author, 2020 Prostaglandin E1 Inhibits GLI2 Amplification-Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth, 5th Author, 2020 GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, 9th Author, 2019 A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease, 4th Author, 2019 Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus, 7th Author, 2019 GA-binding protein GABP beta 1 is required for the proliferation of neural stem/progenitor cells, 9th Author, Corresponding Author, 2019 Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome, 7th Author, 2019 Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2019 MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice, 11th Author, Corresponding Author, 2019 Commentary: Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus., 3rd Author, Corresponding Author, 2018 A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs, 7th Author, 2018 miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds, 7th Author, 2018 Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration., 10th Author, 2018 Partial loss of psychiatric risk gene miR-137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, 30th Author, Corresponding Author, 2018 Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System, 3rd Author, 2018 MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells, 7th Author, Corresponding Author, 2017 The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice., 12th Author, Corresponding Author, 2017 Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury, 2nd Author, 2016

Areas of Focus

Regenerative Medicine
Stem Cells and Brain Injury Repair
Neuroregeneration

Publications

Agomir-331 Suppresses Reactive Gliosis and Neuroinflammation after Traumatic Brain Injury, 6th Author, 2023
Abnormal chromatin remodeling caused by ARID1A deletion leads to malformation of the dentate gyrus, 12th Author, Corresponding Author, 2023
Endothelial Arid1a deletion disrupts the balance among angiogenesis, neurogenesis and gliogenesis in the developing brain, 10th Author, 2023
ASH2L regulates postnatal neurogenesis through Onecut2-mediated inhibition of TGF-& beta; signaling pathway, 11th Author, Corresponding Author, 2023
Microglial transglutaminase 2 deficiency causes impaired synaptic remodelling and cognitive deficits in mice, 10th Author, Corresponding Author, 2023
The Role and Mechanism of Transglutaminase 2 in Regulating Hippocampal Neurogenesis after Traumatic Brain Injury, 11th Author, Corresponding Author, 2023
Mouse model of voluntary movement deficits induced by needlestick injuries to the primary motor cortex, 3rd Author, Corresponding Author, 2022
Decoding the temporal and regional specification of microglia in the developing human brain, 15th Author, 2022
Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 9th Author, Corresponding Author, 2022
Acetate supplementation restores cognitive deficits caused by ARID1A haploinsufficiency in excitatory neurons, 8th Author, Corresponding Author, 2022
Microglial EED is required for synapse engulfment, 14th Author, Corresponding Author, 2022
Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury, 5th Author, Corresponding Author, 2022
A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022
KW-2449 and VPA exert therapeutic effects on human neurons and cerebral organoids derived from MECP2-null hESCs, 7th Author, Corresponding Author, 2022
Loss of microglial EED impairs synapse density, learning, and memory, 14th Author, Corresponding Author, 2022
Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development, 5th Author, Corresponding Author, 2022
A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus, 3rd Author, Corresponding Author, 2022
Intranasal Administration of Agomir-let-7i Improves Cognitive Function in Mice with Traumatic Brain Injury (vol 11, 1348, 2022), 5th Author, Corresponding Author, 2022
miR-26a promotes axon regeneration in the mammalian central nervous system by suppressing PTEN expression, 5th Author, 2021
Transcriptional profiling of microglia in the injured brain reveals distinct molecular features underlying neurodegeneration, 10th Author, Corresponding Author, 2021
TREM2, microglia, and Alzheimer’s disease, 2nd Author, 2021
Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters, 8th Author, Corresponding Author, 2021
Strategies to Promote Long-Distance Optic Nerve Regeneration, 4th Author, 2020
Loss of Arid1a Promotes Neuronal Survival Following Optic Nerve Injury, 7th Author, 2020
Loss of MicroRNA-137 Impairs the Homeostasis of Potassium in Neurons via KCC2, 10th Author, Corresponding Author, 2020
Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2020
UTX Regulates Human Neural Differentiation and Dendritic Morphology by Resolving Bivalent Promoters, 7th Author, Corresponding Author, 2020
SerpinA3N deficiency deteriorates impairments of learning and memory in mice following hippocampal stab injury, 8th Author, Corresponding Author, 2020
Prostaglandin E1 Inhibits GLI2 Amplification-Associated Activation of the Hedgehog Pathway and Drug Refractory Tumor Growth, 5th Author, 2020
GA-binding protein GABPβ1 is required for the proliferation of neural stem/progenitor cells, 9th Author, 2019
A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease, 4th Author, 2019
Polycomb Protein EED Regulates Neuronal Differentiation through Targeting SOX11 in Hippocampal Dentate Gyrus, 7th Author, 2019
GA-binding protein GABP beta 1 is required for the proliferation of neural stem/progenitor cells, 9th Author, Corresponding Author, 2019
Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome, 7th Author, 2019
Regulatory networks between Polycomb complexes and non-coding RNAs in the central nervous system, 4th Author, 2019
MiR-137 Deficiency Causes Anxiety-Like Behaviors in Mice, 11th Author, Corresponding Author, 2019
Commentary: Multiscale Analysis of Independent Alzheimer’s Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus., 3rd Author, Corresponding Author, 2018
A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs, 7th Author, 2018
miR-9 regulates basal ganglia-dependent developmental vocal learning and adult vocal performance in songbirds, 7th Author, 2018
Polycomb protein family member CBX7 regulates intrinsic axon growth and regeneration., 10th Author, 2018
Partial loss of psychiatric risk gene miR-137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a, 30th Author, Corresponding Author, 2018
Polycomb Repressive Complex 2: Emerging Roles in the Central Nervous System, 3rd Author, 2018
MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells, 7th Author, Corresponding Author, 2017
The Histone H3K27 Demethylase UTX Regulates Synaptic Plasticity and Cognitive Behaviors in Mice., 12th Author, Corresponding Author, 2017
Extrinsic and Intrinsic Regulation of Axon Regeneration by MicroRNAs after Spinal Cord Injury, 2nd Author, 2016

Regenerative Medicine Stem Cells Brain Injury Neuroregeneration Neuroscience Cell Proliferation Neuroinflammation Neurogenesis Gliogenesis Traumatic Brain Injury

Zhaoqian Teng - University of Chinese Academy of Sciences

Mengliang Zhou - Nanjing University

Xu Yun - Nanjing University

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