Professor | Xu Yun | Asia Growth Partners

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Name	Xu Yun
Contact Information	xuyun20042001@aliyun.com
Language ability	Chinese, English, German
Province	Jiangsu

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Name

Xu Yun

Contact Information

xuyun20042001@aliyun.com

Language ability

Chinese, English, German

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Medical School
Academic Background & Achievements	Studied at Heidelberg University, Germany Studied at Johns Hopkins University, USA Published over 400 papers 166 SCI papers as corresponding author Total impact factor: 542.145 H-index: 36 7 patents and software copyrights Authored and co-authored 10 books Vice President of Nanjing University Brain Science Institute Director of Jiangsu Provincial Cerebrovascular Disease Treatment Center
Work Experience	Current - Nanjing University Gulou Hospital - Director of Neurology Current - Nanjing University Brain Science Institute - Vice President Current - Jiangsu Provincial Cerebrovascular Disease Treatment Center - Director
Awards	Jiangsu Provincial Science and Technology Award First Prize (2020): Precision Diagnosis and Treatment of Ischemic Stroke Jiangsu Medical Science and Technology Award First Prize (2020): Immune Inflammation Mechanism and Clinical Translation of Ischemic Brain Injury Jiangsu Provincial Health Commission New Technology Introduction Award First Prize (2020): Early Diagnosis of Cerebral Small Vessel Disease with Multimodal MRI Jiangsu Provincial Science and Technology Award Second Prize (2015, 2011): Translational Medical Research on Brain Disease-Related Brain Injury Chinese Medical Award Third Prize (2011): Clinical Translation of Molecular and Imaging Biomarkers for Early Diagnosis of High AD Risk MCI

University/Lab Affiliation and Title

Nanjing University

Faculty

Medical School

Academic Background & Achievements

Studied at Heidelberg University, Germany
Studied at Johns Hopkins University, USA
Published over 400 papers
166 SCI papers as corresponding author
Total impact factor: 542.145
H-index: 36
7 patents and software copyrights
Authored and co-authored 10 books
Vice President of Nanjing University Brain Science Institute
Director of Jiangsu Provincial Cerebrovascular Disease Treatment Center

Work Experience

Current - Nanjing University Gulou Hospital - Director of Neurology
Current - Nanjing University Brain Science Institute - Vice President
Current - Jiangsu Provincial Cerebrovascular Disease Treatment Center - Director

Awards

Jiangsu Provincial Science and Technology Award First Prize (2020): Precision Diagnosis and Treatment of Ischemic Stroke
Jiangsu Medical Science and Technology Award First Prize (2020): Immune Inflammation Mechanism and Clinical Translation of Ischemic Brain Injury
Jiangsu Provincial Health Commission New Technology Introduction Award First Prize (2020): Early Diagnosis of Cerebral Small Vessel Disease with Multimodal MRI
Jiangsu Provincial Science and Technology Award Second Prize (2015, 2011): Translational Medical Research on Brain Disease-Related Brain Injury
Chinese Medical Award Third Prize (2011): Clinical Translation of Molecular and Imaging Biomarkers for Early Diagnosis of High AD Risk MCI

Areas of Focus	Basic and Clinical Research on Cerebrovascular Diseases Basic and Clinical Research on Dementia Basic and Clinical Translational Research on Stem Cells
Publications	Double-negative T cells remarkably promote neuroinflammation after ischemic stroke, Meng H, Zhao H, Cao X, Hao J, Zhang H, Liu Y, Zhu M, Fan L, Weng L, Qian L, Wang X, Xu Y, 2019 HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer’s disease, Zhu X, Wang S, Yu L, Jin J, Ye X, Liu Y, Xu Y, 2017 Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis, Chen J, Jin J, Zhang X, Yu H, Zhu X, Yu L, Chen Y, Liu P, Dong X, Cao X, Gu Y, Bao X, Xia S, Xu Y, 2021 HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by down-regulating the AIM2 inflammasome, Zhang M, Zhao Q, Xia M, Chen J, Chen Y, Cao X, Yuan Z, Wang X, Xu Y, 2020 FasL-PDPK1 pathway promotes the cytotoxicity of CD8+ T cells during ischemic stroke, Fan L, Zhang C, Zhu L, Chen J, Zhang Z, Liu P, Cao X, Meng H, Xu Y, 2020 miR-204-3p/Nox4 Mediates Memory Deficits in a Mouse Model of Alzheimer's Disease, Tao W, Yu L, Shu S, Liu Y, Zhuang Z, Xu S, Bao X, Gu Y, Cai F, Song W, Xu Y, Zhu X, 2021 Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling, Yu H, Cao X, Li W, Liu P, Zhao Y, Song L, Chen J, Chen B, Yu W, Xu Y, 2020 Disrupted functional and structural connectivity within default mode network contribute to WMH-related cognitive impairment, Chen X, Huang Li, Ye Q, Yang D, Qin R, Luo C, Li M, Zhang B, Xu Y, 2019 Progression of White Matter Hyperintensities Contributes to Lacunar Infarction, Xu X, Gao Y, Liu R, Qian L, Chen Y, Wang X, Xu Y, 2018 Sodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage, Ji B, Zhou F, Han L, Yang J, Fan H, Li Shan, Li J, Zhang X, Wang X, Chen X, Xu Y, 2017

Areas of Focus

Basic and Clinical Research on Cerebrovascular Diseases
Basic and Clinical Research on Dementia
Basic and Clinical Translational Research on Stem Cells

Publications

Double-negative T cells remarkably promote neuroinflammation after ischemic stroke, Meng H, Zhao H, Cao X, Hao J, Zhang H, Liu Y, Zhu M, Fan L, Weng L, Qian L, Wang X, Xu Y*, 2019
HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer’s disease, Zhu X, Wang S, Yu L, Jin J, Ye X, Liu Y, Xu Y*, 2017
Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis, Chen J, Jin J, Zhang X, Yu H, Zhu X, Yu L, Chen Y, Liu P, Dong X, Cao X, Gu Y, Bao X, Xia S, Xu Y*, 2021
HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by down-regulating the AIM2 inflammasome, Zhang M, Zhao Q, Xia M, Chen J, Chen Y, Cao X, Yuan Z, Wang X, Xu Y*, 2020
FasL-PDPK1 pathway promotes the cytotoxicity of CD8+ T cells during ischemic stroke, Fan L, Zhang C, Zhu L, Chen J, Zhang Z, Liu P, Cao X, Meng H, Xu Y*, 2020
miR-204-3p/Nox4 Mediates Memory Deficits in a Mouse Model of Alzheimer's Disease, Tao W, Yu L, Shu S, Liu Y, Zhuang Z, Xu S, Bao X, Gu Y, Cai F, Song W, Xu Y*, Zhu X*, 2021
Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling, Yu H, Cao X, Li W, Liu P, Zhao Y, Song L, Chen J, Chen B, Yu W*, Xu Y*, 2020
Disrupted functional and structural connectivity within default mode network contribute to WMH-related cognitive impairment, Chen X, Huang Li, Ye Q, Yang D, Qin R, Luo C, Li M, Zhang B, Xu Y*, 2019
Progression of White Matter Hyperintensities Contributes to Lacunar Infarction, Xu X, Gao Y, Liu R, Qian L, Chen Y, Wang X, Xu Y*, 2018
Sodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage, Ji B, Zhou F, Han L, Yang J, Fan H, Li Shan, Li J, Zhang X, Wang X, Chen X, Xu Y*, 2017

Cerebrovascular Diseases Stroke Ischemia Neuroinflammation Brain Injury Clinical Research Basic Research Translational Research Neurology Therapeutics Dementia Alzheimer'S Disease Cognitive Impairment Neurodegeneration Memory Loss Stem Cells Regenerative Medicine Cell Therapy Neuroregeneration Clinical Trials Cell Biology

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