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Xu Yun
Medical School
Nanjing University
Jiangsu
Language: Chinese, English, German
Cerebrovascular Diseases
Stroke
Ischemia
Neuroinflammation
Brain Injury
Clinical Research
Basic Research
Translational Research
Neurology
Therapeutics
Dementia
Alzheimer'S Disease
Cognitive Impairment
Neurodegeneration
Memory Loss
Stem Cells
Regenerative Medicine
Cell Therapy
Neuroregeneration
Clinical Trials
Cell Biology
Areas of Focus
- Basic and Clinical Research on Cerebrovascular Diseases
- Basic and Clinical Research on Dementia
- Basic and Clinical Translational Research on Stem Cells
Work Experience
- Current - Nanjing University Gulou Hospital - Director of Neurology
- Current - Nanjing University Brain Science Institute - Vice President
- Current - Jiangsu Provincial Cerebrovascular Disease Treatment Center - Director
Academic Background & Achievements
- Studied at Heidelberg University, Germany
- Studied at Johns Hopkins University, USA
- Published over 400 papers
- 166 SCI papers as corresponding author
- Total impact factor: 542.145
- H-index: 36
- 7 patents and software copyrights
- Authored and co-authored 10 books
- Vice President of Nanjing University Brain Science Institute
- Director of Jiangsu Provincial Cerebrovascular Disease Treatment Center
Publications
- Double-negative T cells remarkably promote neuroinflammation after ischemic stroke, Meng H, Zhao H, Cao X, Hao J, Zhang H, Liu Y, Zhu M, Fan L, Weng L, Qian L, Wang X, Xu Y*, 2019
- HDAC3 negatively regulates spatial memory in a mouse model of Alzheimer’s disease, Zhu X, Wang S, Yu L, Jin J, Ye X, Liu Y, Xu Y*, 2017
- Microglial lnc-U90926 facilitates neutrophil infiltration in ischemic stroke via MDH2/CXCL2 axis, Chen J, Jin J, Zhang X, Yu H, Zhu X, Yu L, Chen Y, Liu P, Dong X, Cao X, Gu Y, Bao X, Xia S, Xu Y*, 2021
- HDAC3 inhibitor RGFP966 ameliorated ischemic brain damage by down-regulating the AIM2 inflammasome, Zhang M, Zhao Q, Xia M, Chen J, Chen Y, Cao X, Yuan Z, Wang X, Xu Y*, 2020
- FasL-PDPK1 pathway promotes the cytotoxicity of CD8+ T cells during ischemic stroke, Fan L, Zhang C, Zhu L, Chen J, Zhang Z, Liu P, Cao X, Meng H, Xu Y*, 2020
- miR-204-3p/Nox4 Mediates Memory Deficits in a Mouse Model of Alzheimer's Disease, Tao W, Yu L, Shu S, Liu Y, Zhuang Z, Xu S, Bao X, Gu Y, Cai F, Song W, Xu Y*, Zhu X*, 2021
- Targeting connexin 43 provides anti-inflammatory effects after intracerebral hemorrhage injury by regulating YAP signaling, Yu H, Cao X, Li W, Liu P, Zhao Y, Song L, Chen J, Chen B, Yu W*, Xu Y*, 2020
- Disrupted functional and structural connectivity within default mode network contribute to WMH-related cognitive impairment, Chen X, Huang Li, Ye Q, Yang D, Qin R, Luo C, Li M, Zhang B, Xu Y*, 2019
- Progression of White Matter Hyperintensities Contributes to Lacunar Infarction, Xu X, Gao Y, Liu R, Qian L, Chen Y, Wang X, Xu Y*, 2018
- Sodium Tanshinone IIA Sulfonate Enhances Effectiveness Rt-PA Treatment in Acute Ischemic Stroke Patients Associated with Ameliorating Blood-Brain Barrier Damage, Ji B, Zhou F, Han L, Yang J, Fan H, Li Shan, Li J, Zhang X, Wang X, Chen X, Xu Y*, 2017
Awards
- Jiangsu Provincial Science and Technology Award First Prize (2020): Precision Diagnosis and Treatment of Ischemic Stroke
- Jiangsu Medical Science and Technology Award First Prize (2020): Immune Inflammation Mechanism and Clinical Translation of Ischemic Brain Injury
- Jiangsu Provincial Health Commission New Technology Introduction Award First Prize (2020): Early Diagnosis of Cerebral Small Vessel Disease with Multimodal MRI
- Jiangsu Provincial Science and Technology Award Second Prize (2015, 2011): Translational Medical Research on Brain Disease-Related Brain Injury
- Chinese Medical Award Third Prize (2011): Clinical Translation of Molecular and Imaging Biomarkers for Early Diagnosis of High AD Risk MCI
