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Zhihao Wang
Medical School
Wuhan University
Hubei
Language: English, Chinese
Alzheimer'S Disease
Neurodegeneration
Cognitive Impairment
Neuronal Circuits
Pathogenesis
Delta-Secretase
Tauopathy
Neurobiology
Neurotransmission
Brain Function
Areas of Focus
- Alzheimer's disease
- Neuronal circuit dysfunction in cognitive impairment
Work Experience
- 2015-2015 Visiting Scholar at Emory University
- 2016-2020 Postdoctoral Researcher at Emory University
- 2020-present Professor at Neurology Department, Renmin Hospital, Wuhan University
- 2021-present Director at Neurodegenerative Disease Research Center, Renmin Hospital, Wuhan University
Academic Background & Achievements
- 2005-2010 Bachelor of Clinical Medicine: Tongji Medical College, Huazhong University of Science and Technology
- 2010-2015 PhD: Innovation Research Institute, Huazhong University of Science and Technology
- Published over 40 SCI papers, h-index of 24
Publications
- Neuronal ApoE4 stimulates C/EBPβ activation, promoting Alzheimer's disease pathology in a mouse model, Wang ZH, Xia Y, Wu Z, Kang SS, Zhang JC, Liu P, Liu X, Song W, Huin V, Dhaenens CM, Yu SP, Wang XC, Ye K, 2022
- ApoE4 Activates C/EBPβ/δ-secretase with 27-hydroxycholesterol, Driving the Pathogenesis of Alzheimer’s Disease, Wang ZH, Xia Y, Liu P, Liu X, Edgington-Mitchell L, Lei K, Yu SP, Wang XC, Ye K, 2021
- Delta- and beta- secretases crosstalk amplifies the amyloidogenic pathway in Alzheimer's disease, Xia Y, Wang ZH, Zhang Z, Liu X, Yu SP, Wang JZ, Wang XC, Ye K, 2021
Awards
- 2018 Travel Award at Alzheimer's Association International Conference
- 2017 Distinguished Postdoc Symposium Award at Emory University
