Areas of Focus
- Protein 3D Structure
- Molecular Biology
Work Experience
- 2011-07~Present - Chinese Academy of Sciences Shanghai Institute of Materia Medica - Researcher
- 2007-04~2011-07 - The Scripps Research Institute, USA - Research Assistant
- 2001-09~2006-07 - Tsinghua University - PhD
- 1997-09~2001-07 - Beijing Normal University - Bachelor's
- 1994-09~1997-07 - Wuxi No.1 High School, Jiangsu Province - High School Graduate
Academic Background & Achievements
- 2001-09--2006-07 PhD: Tsinghua University
- 1997-09--2001-07 Bachelor's: Beijing Normal University
- 1994-09--1997-07 High School Graduate: Wuxi No.1 High School, Jiangsu Province
Publications
- Structural insights into dimerization and activation of the mGlu2-mGlu3 and mGlu2-mGlu4 heterodimers, Beili Wu, 2023
- Structural insights into signal transduction of the purinergic receptors P2Y_(1)R and P2Y_(12)R, Beili Wu, 2023
- Tail engagement of arrestin at the glucagon receptor, Beili Wu, 2023
- High-throughput screening of SARS-CoV-2 main and papain-like protease inhibitors, Beili Wu, 2023
- Activation of the human chemokine receptor CX3CR1 regulated by cholesterol, Beili Wu, 2022
- Receptor-specific recognition of NPY peptides revealed by structures of NPY receptors, Beili Wu, 2022
- Structural insights into ligand recognition and selectivity of somatostatin receptors, Beili Wu, 2022
- Structural insights into multiplexed pharmacological actions of tirzepatide and peptide 20 at the GIP, GLP-1 or glucagon receptors, Beili Wu, 2022
- Structures of the human cholecystokinin receptors bound to agonists and antagonists, Beili Wu, 2021
- Structures of human mGlu2 and mGlu7 homo- and heterodimers, Beili Wu, 2021
- Structural basis for ligand recognition of the neuropeptide Y Y-2 receptor, Beili Wu, 2021
- Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor, Beili Wu, 2021
- Structures of Gi-bound metabotropic glutamate receptors mGlu2 and mGlu4, Beili Wu, 2021
- Structural basis for chemokine recognition and receptor activation of chemokine receptor CCR5, Beili Wu, 2021
- GPR91, a critical signaling mechanism in modulating pathophysiologic processes in chronic illnesses, Beili Wu, 2020
- Mechanochemical Activation of Class-B G-Protein-Coupled Receptor upon Peptide-Ligand Binding, Beili Wu, 2020
- Anti-inflammatory signaling through G protein-coupled receptors, Beili Wu, 2020
- Structural basis of ligand binding modes at the human formyl peptide receptor 2, Beili Wu, 2020
- Structural basis of G(s) and G(i) recognition by the human glucagon receptor, Beili Wu, 2020
- Update of P2Y receptor pharmacology: IUPHAR Review 27, Beili Wu, 2020
- Editorial overview: New insights into membrane protein machineries from technology revolution, Beili Wu, 2020
- Cryo-electron microscopy structure of the glucagon receptor with a dual-agonist peptide, Beili Wu, 2020
- Human substance P receptor binding mode of the antagonist drug aprepitant by NMR and crystallography, Beili Wu, 2019
- Advancing Chemokine GPCR Structure Based Drug Discovery, Beili Wu, 2019
- Structural basis for ligand recognition of the human thromboxane A(2) receptor, Beili Wu, 2019
- Molecular binding mode of PF-232798, a clinical anti-HIV candidate, at chemokine receptor CCR5, Beili Wu, 2019
- Disparate impact on CD4 T cell count by two distinct HIV-1 phylogenetic clusters from the same Glade, Beili Wu, 2019
- Structural basis of ligand binding modes at the neuropeptide Y Y 1 receptor, Beili Wu, 2018
- Structure of the glucagon receptor in complex with a glucagon analogue, Beili Wu, 2018
- Peptide recognition, signaling and modulation of class B G protein-coupled receptors, Beili Wu, 2018
- Structure-Based Design of 1-Heteroary1-1,3-propanediamine Derivatives as a Novel Series of CC-Chemokine Receptor 5 Antagonists, Beili Wu, 2018
- Structural basis for signal recognition and transduction by platelet-activating-factor receptor, Beili Wu, 2018
- G蛋白偶联受体的结构研究与药物研发, Beili Wu, 2018
- Extending the Structural View of Class B GPCRs, Beili Wu, 2017
- Structure of CC Chemokine Receptor 5 with a Potent Chemokine Antagonist Reveals Mechanisms of Chemokine Recognition and Molecular Mimicry by HIV, Beili Wu, 2017
- Ligand binding to a G protein-coupled receptor captured in a mass spectrometer, Beili Wu, 2017
- Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators, Beili Wu, 2017
- Structure of the full-length glucagon class B G-protein-coupled receptor, Beili Wu, 2017
- G蛋白偶联受体的结构生物学研究, Beili Wu, 2016
- Structural Studies of G Protein-Coupled Receptors, Beili Wu, 2016
- High-resolution mass spectrometry of small molecules bound to membrane proteins, Beili Wu, 2016
- Staphylococcus aureus Leukocidin LukED and HIV-1 gp120 Target Different Sequence Determinants on CCR5, Beili Wu, 2016
- Crystal Structure of the Human Cannabinoid Receptor CB1, Beili Wu, 2016
- Two disparate ligand binding sites in the human P2Y 1 receptor, Beili Wu, 2015
- Nucleotides Acting at P2Y Receptors: Connecting Structure
Awards
- Shanghai Natural Science Award (2020): First Prize, Provincial Level
- China Youth Science and Technology Award (2020): National Level
- Chen Jiageng Youth Science Award (2018): National Level
- He Liang He Li Foundation Youth Innovation Award (2018): Other
- Chinese Academy of Sciences Youth Scientist Award (2018): Ministerial Level
- Shanghai Youth Science and Technology Talent (2016): Provincial Level
- Shulan Medical Youth Award (2016): Other
- Shanghai March 8th Red Banner Holder (2016): Provincial Level
- China Youth Female Scientist Award (2015): National Level
- Chinese Academy of Sciences Shanghai Branch Fourth Outstanding Youth Science and Technology Innovation Talent (2014): Institute Level
- Roche Chinese Young Investigator Award (2014): Other
- Tan Jiazhen Life Science Innovation Award (2014): Other
- WuXi AppTec Life Chemistry Research Award (2014): First Prize, Other
- Shanghai Science and Technology System May Fourth Medal (2013): Municipal Level
