Upload Avatar (500 x 500)
Jianchao Zhang
Medical School
Southern University of Science and Technology
Guangdong
Language: Chinese, English
Tumor
Occurrence
Metastasis
Molecular
Mechanisms
Cancer
Biology
Cell
Biochemistry
Molecular Biology
Areas of Focus
- Molecular mechanisms of tumor occurrence and metastasis
Work Experience
- 2021.01-present: Southern University of Science and Technology, Medical School, Research Assistant Professor
- 2017.04-2020.12: Shenzhen University, Medical Department, Associate Researcher
- 2014.10-2017.04: Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Postdoctoral/Assistant Researcher
- 2014.05-2014.09: Xuzhou Medical College, Assistant Researcher
- 2013.09-2014.03: National Cancer Institute, USA, Postdoctoral
Academic Background & Achievements
- 2008-2013 PhD in Cell Biology, Northeast Normal University
- 2013 Doctoral Degree, Northeast Normal University
- Hosted 1 National Natural Science Foundation project, 1 China Postdoctoral Science Foundation project, 1 Guangdong Provincial Natural Science Foundation project, and 2 Shenzhen Science and Technology projects
Publications
- Aurora B induces epithelial–mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis, Jianchao Zhang, Xinxin Lin, Liufeng Wu, Jia-Jia Huang, Wen-qi Jiang, Thomas Kipps, and Suping Zhang, 2020
- NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling, Jianchao Zhang, Ximing Shao, Haiyan Sun, Ke Liu, Zhihao Ding, Juntao Chen, Lijing Fang, Wu Su, Yang Hong, Huashun Li and Hongchang Li, 2016
- SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression, Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu, and Baiqu Huang, 2012
- p53 attenuates the oncogenic ras-induced epithelial-mesenchymal transition in human mammary epithelial cells, Jianchao Zhang, Yang Lei, Xiaoge Gao, Qian Liang, Lili Li, Jingxin Feng, Yu Zhang, Baiqu Huang, and Jun Lu, 2013
- Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody, Suping Zhang, Han Zhang, Emanuela M. Ghia, Jiajia Huang, Liufeng Wu, Jianchao Zhang, Sharon Lam, Yang Lei, Jinsong He, Bing Cui, George F. Widhopf II, Jian Yu, Richard Schwab, Karen Messer, Wenqi Jiang, Barbara A. Parker, Dennis A. Carson, and Thomas J. Kipps, 2019
- Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b, Ximing Shao, Yi Liu, Qian Yu, Zhihao Ding, Wenyu Qian, Lei Zhang, Jianchao Zhang, Nan Jiang, Linfei Gui, Zhiheng Xu, Yang Hong, Yifan Ma, Yanjie Wei, Xiaoqing Liu, Changan Jiang, Minyan Zhu, Hongchang Li and Huashun Li, 2016
- CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression, Qian Liang, Lili Li, Jianchao Zhang, Yang Lei, Liping Wang, Dong-Xu Liu, Jingxin Feng, Pingfu Hou, Ruosi Yao, Yu Zhang, Baiqu Huang, and Jun Lu, 2013
- Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer, Jingxin Feng, Guiying Xu, Jiwei Liu, Na Zhang, Lili Li, Jiafei Ji, Jianchao Zhang, Lian Zhang, Guannan Wang, Xiuli Wang, Jiang Tan, Baiqu Huang, Jun Lu, Yu Zhang, 2016
- Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo, Ke Liu, Lijing Fang, Haiyan Sun, Zhengyin Pan, Jianchao Zhang, Juntao Chen, Ximing Shao, Wei Wang, Yuanyan Tan, Zhihao Ding, Lijiao Ao, Chunlei Wu, Xiaoqi Liu, Huashun Li, Rui Wang, Wu Su, and Hongchang Li, 2018
- Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity, Ke Liu, Run Lei, Qiong Li, Xin-Xin Wang, Qian Wu, Peng An, Jianchao Zhang, Minyan Zhu, Zhiheng Xu, Yang Hong, Fudi Wang, Ying Shen, Hongchang Li, and Huashun Li, 2016
- Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression, Ke Liu, Quan Lin, Yanxia Wei, Renbing He, Ximing Shao, Zhihao Ding, Jianchao Zhang, Minyan Zhu, Lee S. Weinstein, Yang Hong, Hongchang Li, Huashun Li, 2015
- DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells, Yu Zhang, Yanyan Gao, Guoping Zhang, Shuyan Huang, Zhixiong Dong, Chenfei Kong, Dongmei Su, Juan Du, Shan Zhu, Qian Liang, Jianchao Zhang, Jun Lu and Baiqu Huang, 2011
- Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells, Dongmei Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang, Qian Liang, Jun Lu, Baiqu Huang, 2010
- c-Myc attenuates the ability of doxorubicin to reduce the colony formation partially through regulating Nbs1 in U2OS cells, Hanqing Shi, Hui Huang, Xitao Zhang, Jianchao Zhang, Xiutan Luo, Xiue Peng, Baiqu Huang, Jun Lu, 2010
Awards
- 2017 November, First Prize of Jilin Province Science and Technology Award (Ranked 4th)
- 2015 October, Second Prize of Jilin Province Natural Science Academic Achievement (Ranked 4th)
- 2015 October, 2015 Jilin Province Outstanding Doctoral Thesis
- 2013 June, Northeast Normal University 2013 Doctoral Research Award First Prize
- 2013 June, Northeast Normal University Outstanding Graduate Student
- 2012-2013 Academic Year, Northeast Normal University Outstanding Graduate Student
- 2012-2013 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship
- 2012 December, Ministry of Education Doctoral National Scholarship
- 2011-2012 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship
- 2009-2010 Academic Year, Northeast Normal University Academic Activity Advanced Individual
- 2009-2010 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship
