Professor | Jianchao Zhang | Asia Growth Partners

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Name	Jianchao Zhang
Contact Information	zhangjc3@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

Upload Avatar (500 x 500)

Name

Jianchao Zhang

Contact Information

zhangjc3@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	2008-2013 PhD in Cell Biology, Northeast Normal University 2013 Doctoral Degree, Northeast Normal University Hosted 1 National Natural Science Foundation project, 1 China Postdoctoral Science Foundation project, 1 Guangdong Provincial Natural Science Foundation project, and 2 Shenzhen Science and Technology projects
Work Experience	2021.01-present: Southern University of Science and Technology, Medical School, Research Assistant Professor 2017.04-2020.12: Shenzhen University, Medical Department, Associate Researcher 2014.10-2017.04: Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Postdoctoral/Assistant Researcher 2014.05-2014.09: Xuzhou Medical College, Assistant Researcher 2013.09-2014.03: National Cancer Institute, USA, Postdoctoral
Awards	2017 November, First Prize of Jilin Province Science and Technology Award (Ranked 4th) 2015 October, Second Prize of Jilin Province Natural Science Academic Achievement (Ranked 4th) 2015 October, 2015 Jilin Province Outstanding Doctoral Thesis 2013 June, Northeast Normal University 2013 Doctoral Research Award First Prize 2013 June, Northeast Normal University Outstanding Graduate Student 2012-2013 Academic Year, Northeast Normal University Outstanding Graduate Student 2012-2013 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship 2012 December, Ministry of Education Doctoral National Scholarship 2011-2012 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship 2009-2010 Academic Year, Northeast Normal University Academic Activity Advanced Individual 2009-2010 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

2008-2013 PhD in Cell Biology, Northeast Normal University
2013 Doctoral Degree, Northeast Normal University
Hosted 1 National Natural Science Foundation project, 1 China Postdoctoral Science Foundation project, 1 Guangdong Provincial Natural Science Foundation project, and 2 Shenzhen Science and Technology projects

Work Experience

2021.01-present: Southern University of Science and Technology, Medical School, Research Assistant Professor
2017.04-2020.12: Shenzhen University, Medical Department, Associate Researcher
2014.10-2017.04: Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Postdoctoral/Assistant Researcher
2014.05-2014.09: Xuzhou Medical College, Assistant Researcher
2013.09-2014.03: National Cancer Institute, USA, Postdoctoral

Awards

2017 November, First Prize of Jilin Province Science and Technology Award (Ranked 4th)
2015 October, Second Prize of Jilin Province Natural Science Academic Achievement (Ranked 4th)
2015 October, 2015 Jilin Province Outstanding Doctoral Thesis
2013 June, Northeast Normal University 2013 Doctoral Research Award First Prize
2013 June, Northeast Normal University Outstanding Graduate Student
2012-2013 Academic Year, Northeast Normal University Outstanding Graduate Student
2012-2013 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship
2012 December, Ministry of Education Doctoral National Scholarship
2011-2012 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship
2009-2010 Academic Year, Northeast Normal University Academic Activity Advanced Individual
2009-2010 Academic Year, Northeast Normal University Graduate Student Excellence Scholarship

Areas of Focus	Molecular mechanisms of tumor occurrence and metastasis
Publications	Aurora B induces epithelial–mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis, Jianchao Zhang, Xinxin Lin, Liufeng Wu, Jia-Jia Huang, Wen-qi Jiang, Thomas Kipps, and Suping Zhang, 2020 NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling, Jianchao Zhang, Ximing Shao, Haiyan Sun, Ke Liu, Zhihao Ding, Juntao Chen, Lijing Fang, Wu Su, Yang Hong, Huashun Li and Hongchang Li, 2016 SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression, Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu, and Baiqu Huang, 2012 p53 attenuates the oncogenic ras-induced epithelial-mesenchymal transition in human mammary epithelial cells, Jianchao Zhang, Yang Lei, Xiaoge Gao, Qian Liang, Lili Li, Jingxin Feng, Yu Zhang, Baiqu Huang, and Jun Lu, 2013 Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody, Suping Zhang, Han Zhang, Emanuela M. Ghia, Jiajia Huang, Liufeng Wu, Jianchao Zhang, Sharon Lam, Yang Lei, Jinsong He, Bing Cui, George F. Widhopf II, Jian Yu, Richard Schwab, Karen Messer, Wenqi Jiang, Barbara A. Parker, Dennis A. Carson, and Thomas J. Kipps, 2019 Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b, Ximing Shao, Yi Liu, Qian Yu, Zhihao Ding, Wenyu Qian, Lei Zhang, Jianchao Zhang, Nan Jiang, Linfei Gui, Zhiheng Xu, Yang Hong, Yifan Ma, Yanjie Wei, Xiaoqing Liu, Changan Jiang, Minyan Zhu, Hongchang Li and Huashun Li, 2016 CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression, Qian Liang, Lili Li, Jianchao Zhang, Yang Lei, Liping Wang, Dong-Xu Liu, Jingxin Feng, Pingfu Hou, Ruosi Yao, Yu Zhang, Baiqu Huang, and Jun Lu, 2013 Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer, Jingxin Feng, Guiying Xu, Jiwei Liu, Na Zhang, Lili Li, Jiafei Ji, Jianchao Zhang, Lian Zhang, Guannan Wang, Xiuli Wang, Jiang Tan, Baiqu Huang, Jun Lu, Yu Zhang, 2016 Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo, Ke Liu, Lijing Fang, Haiyan Sun, Zhengyin Pan, Jianchao Zhang, Juntao Chen, Ximing Shao, Wei Wang, Yuanyan Tan, Zhihao Ding, Lijiao Ao, Chunlei Wu, Xiaoqi Liu, Huashun Li, Rui Wang, Wu Su, and Hongchang Li, 2018 Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity, Ke Liu, Run Lei, Qiong Li, Xin-Xin Wang, Qian Wu, Peng An, Jianchao Zhang, Minyan Zhu, Zhiheng Xu, Yang Hong, Fudi Wang, Ying Shen, Hongchang Li, and Huashun Li, 2016 Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression, Ke Liu, Quan Lin, Yanxia Wei, Renbing He, Ximing Shao, Zhihao Ding, Jianchao Zhang, Minyan Zhu, Lee S. Weinstein, Yang Hong, Hongchang Li, Huashun Li, 2015 DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells, Yu Zhang, Yanyan Gao, Guoping Zhang, Shuyan Huang, Zhixiong Dong, Chenfei Kong, Dongmei Su, Juan Du, Shan Zhu, Qian Liang, Jianchao Zhang, Jun Lu and Baiqu Huang, 2011 Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells, Dongmei Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang, Qian Liang, Jun Lu, Baiqu Huang, 2010 c-Myc attenuates the ability of doxorubicin to reduce the colony formation partially through regulating Nbs1 in U2OS cells, Hanqing Shi, Hui Huang, Xitao Zhang, Jianchao Zhang, Xiutan Luo, Xiue Peng, Baiqu Huang, Jun Lu, 2010

Areas of Focus

Molecular mechanisms of tumor occurrence and metastasis

Publications

Aurora B induces epithelial–mesenchymal transition by stabilizing Snail1 to promote basal-like breast cancer metastasis, Jianchao Zhang, Xinxin Lin, Liufeng Wu, Jia-Jia Huang, Wen-qi Jiang, Thomas Kipps, and Suping Zhang, 2020
NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling, Jianchao Zhang, Ximing Shao, Haiyan Sun, Ke Liu, Zhihao Ding, Juntao Chen, Lijing Fang, Wu Su, Yang Hong, Huashun Li and Hongchang Li, 2016
SOX4 induces epithelial-mesenchymal transition and contributes to breast cancer progression, Jianchao Zhang, Qian Liang, Yang Lei, Min Yao, Lili Li, Xiaoge Gao, Jingxin Feng, Yu Zhang, Hongwen Gao, Dong-Xu Liu, Jun Lu, and Baiqu Huang, 2012
p53 attenuates the oncogenic ras-induced epithelial-mesenchymal transition in human mammary epithelial cells, Jianchao Zhang, Yang Lei, Xiaoge Gao, Qian Liang, Lili Li, Jingxin Feng, Yu Zhang, Baiqu Huang, and Jun Lu, 2013
Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody, Suping Zhang, Han Zhang, Emanuela M. Ghia, Jiajia Huang, Liufeng Wu, Jianchao Zhang, Sharon Lam, Yang Lei, Jinsong He, Bing Cui, George F. Widhopf II, Jian Yu, Richard Schwab, Karen Messer, Wenqi Jiang, Barbara A. Parker, Dennis A. Carson, and Thomas J. Kipps, 2019
Numb regulates vesicular docking for homotypic fusion of early endosomes via membrane recruitment of Mon1b, Ximing Shao, Yi Liu, Qian Yu, Zhihao Ding, Wenyu Qian, Lei Zhang, Jianchao Zhang, Nan Jiang, Linfei Gui, Zhiheng Xu, Yang Hong, Yifan Ma, Yanjie Wei, Xiaoqing Liu, Changan Jiang, Minyan Zhu, Hongchang Li and Huashun Li, 2016
CDK5 is essential for TGF-β1-induced epithelial-mesenchymal transition and breast cancer progression, Qian Liang, Lili Li, Jianchao Zhang, Yang Lei, Liping Wang, Dong-Xu Liu, Jingxin Feng, Pingfu Hou, Ruosi Yao, Yu Zhang, Baiqu Huang, and Jun Lu, 2013
Phosphorylation of LSD1 at Ser112 is crucial for its function in induction of EMT and metastasis in breast cancer, Jingxin Feng, Guiying Xu, Jiwei Liu, Na Zhang, Lili Li, Jiafei Ji, Jianchao Zhang, Lian Zhang, Guannan Wang, Xiuli Wang, Jiang Tan, Baiqu Huang, Jun Lu, Yu Zhang, 2016
Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo, Ke Liu, Lijing Fang, Haiyan Sun, Zhengyin Pan, Jianchao Zhang, Juntao Chen, Ximing Shao, Wei Wang, Yuanyan Tan, Zhihao Ding, Lijiao Ao, Chunlei Wu, Xiaoqi Liu, Huashun Li, Rui Wang, Wu Su, and Hongchang Li, 2018
Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity, Ke Liu, Run Lei, Qiong Li, Xin-Xin Wang, Qian Wu, Peng An, Jianchao Zhang, Minyan Zhu, Zhiheng Xu, Yang Hong, Fudi Wang, Ying Shen, Hongchang Li, and Huashun Li, 2016
Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression, Ke Liu, Quan Lin, Yanxia Wei, Renbing He, Ximing Shao, Zhihao Ding, Jianchao Zhang, Minyan Zhu, Lee S. Weinstein, Yang Hong, Hongchang Li, Huashun Li, 2015
DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells, Yu Zhang, Yanyan Gao, Guoping Zhang, Shuyan Huang, Zhixiong Dong, Chenfei Kong, Dongmei Su, Juan Du, Shan Zhu, Qian Liang, Jianchao Zhang, Jun Lu and Baiqu Huang, 2011
Role of p38 MAPK pathway in BMP4-mediated Smad-dependent premature senescence in lung cancer cells, Dongmei Su, Xiue Peng, Shan Zhu, Ying Huang, Zhixiong Dong, Yu Zhang, Jianchao Zhang, Qian Liang, Jun Lu, Baiqu Huang, 2010
c-Myc attenuates the ability of doxorubicin to reduce the colony formation partially through regulating Nbs1 in U2OS cells, Hanqing Shi, Hui Huang, Xitao Zhang, Jianchao Zhang, Xiutan Luo, Xiue Peng, Baiqu Huang, Jun Lu, 2010

Tumor Occurrence Metastasis Molecular Mechanisms Cancer Biology Cell Biochemistry Molecular Biology

Guoan Chen - Southern University of Science and Technology

Hao Chen - Southern University of Science and Technology

Jin Tang Dong - Southern University of Science and Technology

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