Professor | Hao Chen | Asia Growth Partners

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Name	Hao Chen
Contact Information	chenh7@sustech.edu.cn
Language ability	Chinese, English
Province	Guangdong

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Name

Hao Chen

Contact Information

chenh7@sustech.edu.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	Southern University of Science and Technology
Faculty	Medical School
Academic Background & Achievements	2004-2008 Bachelor: Wuhan University 2008-2013 PhD: Fudan University Biomedical Research Institute Postdoctoral training at Harvard Medical School (2015-2019)
Work Experience	2013.07-2014.11 - Fudan University - Assistant Researcher 2015.02-2019.12 - Harvard University, Boston Children's Hospital - Postdoctoral Researcher 2020.05-present - Southern University of Science and Technology - Assistant Professor
Awards	2013: Outstanding Graduate - Fudan University 2013: Best Presentation Award - Tumor Biology and Translational Medicine Forum 2012: National Scholarship - Ministry of Education of China 2012: Best Presentation Award - Shanghai Life Science Forum

University/Lab Affiliation and Title

Southern University of Science and Technology

Faculty

Medical School

Academic Background & Achievements

2004-2008 Bachelor: Wuhan University
2008-2013 PhD: Fudan University Biomedical Research Institute
Postdoctoral training at Harvard Medical School (2015-2019)

Work Experience

2013.07-2014.11 - Fudan University - Assistant Researcher
2015.02-2019.12 - Harvard University, Boston Children's Hospital - Postdoctoral Researcher
2020.05-present - Southern University of Science and Technology - Assistant Professor

Awards

2013: Outstanding Graduate - Fudan University
2013: Best Presentation Award - Tumor Biology and Translational Medicine Forum
2012: National Scholarship - Ministry of Education of China
2012: Best Presentation Award - Shanghai Life Science Forum

Areas of Focus	Epigenetic mechanisms of disease occurrence Identification and functional study of novel epigenetic modifications
Publications	The 18S rRNA m6A methyltransferase regulates mouse embryonic stem cell differentiation, Xing, M., Liu, Q., Mao, C., Zeng, H., Zhang, X., Zhao, S., Chen, L., Liu, M., Shen, B., Guo, X., Ma, H., Chen, H., Zhang, J., 2020 METTL4 is an m6Am methyltransferase that regulates RNA splicing, Chen, H., Gu, L., Orellana, E., Wang, Y., Guo, J., Liu, Q., Gregory, R., Xing, Y., Shi, Y., 2020 The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for proper mitochondrial function, Chen, H., Shi, Guo, J., Chang, K., Chen, Q., Yao, C., Haigis, M., Shi, Y., 2020 CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila, Gu, L., Wang, L., Chen, H., Hong, J., Shen, Z., Dhall, A., Lao, T., Wu, H., Shi, Y., 2020 METTL5, an 18S rRNA-specific m6A methyltransferase, modulates expression of stress response genes, Chen, H., Liu, Q., Yu, D., Natchiar, K., Zhou, C., Hsu, C.-h., Hsu, P.-H., Zhang, X., Klaholz, B., Gregory, R., Shi, Y., 2020 TET2stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer, Chen, H., Yu, D., Fang, R., Rabidou, K., Wu, D., Hu, D., Shi, Y. G., 2019 Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer, Wu, D., Hu, D., Chen, H., Shi, G., Fetahu, I. S., Wu, F., Shi, Y. G., 2018 PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression, Sendinc, E., Valle-Garcia, D., Dhall, A., Chen, H., Henriques, T., Navarrete-Perea, J., Sheng, W., Gygi, S., Adelman, K., Shi, Y., 2019 N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation, Ma, H., Wang, X., Cai, J., Dai, Q., Natchiar, S. K., Lv, R., Chen, H., He, C., 2019 Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway, Lee, Y., Chen, M., Lee, J., Zhang, J., Lin, S., Fu, T., Chen, H., Ishikawa, T., Chiang, S., Katon, J., Wei W., Pandolfi P., 2019

Areas of Focus

Epigenetic mechanisms of disease occurrence
Identification and functional study of novel epigenetic modifications

Publications

The 18S rRNA m6A methyltransferase regulates mouse embryonic stem cell differentiation, Xing, M., Liu, Q., Mao, C., Zeng, H., Zhang, X., Zhao, S., Chen, L., Liu, M., Shen, B., Guo, X., Ma, H., Chen, H., Zhang, J., 2020
METTL4 is an m6Am methyltransferase that regulates RNA splicing, Chen, H., Gu, L., Orellana, E., Wang, Y., Guo, J., Liu, Q., Gregory, R., Xing, Y., Shi, Y., 2020
The human mitochondrial 12S rRNA m4C methyltransferase METTL15 is required for proper mitochondrial function, Chen, H., Shi, Guo, J., Chang, K., Chen, Q., Yao, C., Haigis, M., Shi, Y., 2020
CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila, Gu, L., Wang, L., Chen, H., Hong, J., Shen, Z., Dhall, A., Lao, T., Wu, H., Shi, Y., 2020
METTL5, an 18S rRNA-specific m6A methyltransferase, modulates expression of stress response genes, Chen, H., Liu, Q., Yu, D., Natchiar, K., Zhou, C., Hsu, C.-h., Hsu, P.-H., Zhang, X., Klaholz, B., Gregory, R., Shi, Y., 2020
TET2stabilization by 14-3-3 binding to the phosphorylated Serine 99 is deregulated by mutations in cancer, Chen, H., Yu, D., Fang, R., Rabidou, K., Wu, D., Hu, D., Shi, Y. G., 2019
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer, Wu, D., Hu, D., Chen, H., Shi, G., Fetahu, I. S., Wu, F., Shi, Y. G., 2018
PCIF1 catalyzes m6Am mRNA methylation to regulate gene expression, Sendinc, E., Valle-Garcia, D., Dhall, A., Chen, H., Henriques, T., Navarrete-Perea, J., Sheng, W., Gygi, S., Adelman, K., Shi, Y., 2019
N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation, Ma, H., Wang, X., Cai, J., Dai, Q., Natchiar, S. K., Lv, R., Chen, H., He, C., 2019
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway, Lee, Y., Chen, M., Lee, J., Zhang, J., Lin, S., Fu, T., Chen, H., Ishikawa, T., Chiang, S., Katon, J., Wei W., Pandolfi P., 2019

Epigenetics Disease Mechanisms Identification Modifications Functional Study Cancer Metabolic Diseases Diabetes Hypertension

Jun Che - Southern University of Science and Technology

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