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Jun Tian
Medical School
Southern University of Science and Technology
Guangdong
Language: English, Chinese
Cancer
Targeted Therapy
Immunotherapy
Drug Resistance
Mechanisms
Tumor
Organoid Models
Drug Testing
Oncology
Therapeutic Strategies
Areas of Focus
- Cancer targeted and immunotherapy
- Drug resistance mechanisms
- Development of tumor organoid models and drug testing
Work Experience
- 2023.08-present Southern University of Science and Technology, Medical School, Assistant Professor
- 2019-2023 Harvard Medical School, Massachusetts General Hospital, Postdoctoral Researcher
- 2018-2019 McGill University Health Centre, Postdoctoral Researcher
Academic Background & Achievements
- 2009-2013 Bachelor: Nankai University
- 2013-2018 PhD: McGill University, Canada
- Received Outstanding PhD Graduate Award from McGill University
Publications
- Combined PD-1, BRAF and MEK inhibition in BRAFV600E colorectal cancer: a phase 2 trial, Jun Tian et al., 2023
- Targeting TBK1 to overcome resistance to cancer immunotherapy, Jun Tian et al., 2023
- Identification of MFGE8 and KLK5/7 as mediators of breast tumorigenesis and resistance to COX-2 inhibition, Jun Tian et al., 2021
- Prolactin receptor-driven combined luminal and epithelial differentiation in breast cancer restricts plasticity, stemness, tumorigenesis and metastasis, Jun Tian et al., 2021
- Dasatinib sensitises triple negative breast cancer cells to chemotherapy by targeting breast cancer stem cells, Jun Tian et al., 2018
- KiSS1 gene as a novel mediator of TGFβ-mediated cell invasion in triple negative breast cancer, Jun Tian et al., 2018
- Cyclooxygenase-2 regulates TGFβ-induced cancer stemness in triple-negative breast cancer, Jun Tian et al., 2017
- Critical Role of Myeloid-Derived Suppressor Cells in Tumor-Induced Liver Immune Suppression through Inhibition of NKT Cell Function, Jun Tian et al., 2017
- The leukemia inhibitory factor (LIF) and p21 mediate the TGFβ tumor suppressive effects in human cutaneous melanoma, Jun Tian et al., 2015
- Breast cancer anti-estrogen resistance 3 inhibits transforming growth factor β/Smad signaling and associates with favorable breast cancer disease outcomes, Jun Tian et al., 2014
Awards
- 2018: Outstanding PhD Graduate Award, McGill University
- 2017: Excellent Productivity Award, McGill University Medical School
