Areas of Focus
- Cardiovascular diseases and cancer occurrence: 3D genomics and epigenetic regulation
Work Experience
- 2022.11-Present Associate Professor, Department of Pharmacology, Southern University of Science and Technology
- 2017.03-2019.07 Postdoctoral Researcher, Department of Genomic Sciences, The Jackson Laboratory, USA
- 2014.10-2016.06 Postdoctoral Researcher, Department of Molecular Biology, Radboud University, Netherlands
- 2010.01-2014.02 Postdoctoral Researcher, Department of Pathology, University of Cincinnati, USA
Academic Background & Achievements
- 2019.10-2022.11 PhD in Molecular and Cellular Medicine, University of Oxford
- 2008.09-2014.06 PhD in Pharmacology, Southern Medical University
- 2003.09-2008.06 Bachelor of Medicine in Preventive Medicine, Sun Yat-sen University
Publications
- Contribution of leukocyte telomere length to major cardiovascular diseases onset: phenotypic and genetic insights from a large-scale genome-wide cross-trait analysis, Jun Qiao, Qian Wang, Yuhui Zhao, Minjing Chang, Liuyang Cai, Feng Liu, Kaixin Yao, Leilei Zheng, Ning Tan, Pengcheng He, Anil G. Jegga, Siim Pauklin, Lei Jiang, Yining Yang, Yuliang Feng, 2024
- Targeted modulation of intestinal epithelial regeneration and immune response in ulcerative colitis using dual-targeting bilirubin nanoparticles, Zhuo Z, Guo K, Luo Y, Yang Q, Wu H, Zeng R, Jiang R, Li J, Wei R, Lian Q, Sha W, Feng Y, Chen H, 2024
- BRD9-SMAD2/3 orchestrates stemness and tumorigenesis in pancreatic ductal adenocarcinoma, Feng Y, Cai L, Pook M, Liu F, Chang CH, Mouti MA, Nibhani R, Militi S, Dunford J, Philpott M, Fan Y, Fan GC, Liu Q, Qi J, Wang C, Hong W, Morgan H, Wang M, Sadayappan S, Jegga AG, Oppermann U, Wang Y, Huang W, Jiang L, Pauklin S, 2023
- Shared Genetic Architecture Contributes to Risk of Major Cardiovascular Diseases, Jun Qiao, Liuyang Cai, Minjing Chang, Can Wang, Rong Zhao, Shan Song, Ning Tan, Pengcheng He, Siim Pauklin, Lei Jiang, Yuliang Feng, 2023
- Genetic risk, adherence to healthy lifestyle and acute cardiovascular and thromboembolic complications following SARS-COV-2 infection, Xie J, Feng Y, Newby D, Zheng B, Feng Q, Prats-Uribe A, Li C, Wareham NJ, Paredes R, Prieto-Alhambra D, 2023
- Associations of habitual glucosamine use with SARS-CoV-2 infection and hospital admission and death with COVID-19: Evidence from a large population based cohort study, Meng M, Wu Y, Sha W, Zeng R, Luo D, Jiang R, Wu H, Zhuo Z, Yang Q, Li J, Leung FW, Duan C, Feng Y, Chen H, 2023
- Epigenetic and transcriptional regulations prime cell fate before division during human pluripotent stem cell differentiation, Madrigal P, Deng S, Feng Y, Militi S, Goh KJ, Nibhani R, Grandy R, Osnato A, Ortmann D, Brown S, Pauklin S, 2023
- Rewiring of 3D Chromatin Topology Orchestrates Transcriptional Reprogramming and the Development of Human Dilated Cardiomyopathy, Feng Y, Cai L, Hong W, Zhang C, Tan N, Wang M, Wang C, Liu F, Wang X, Ma J, Gao C, Kumar N, Mo Y, Geng Q, Luo C, Lin Y, Chen H, Wang S, Watson M, Jegga A, Pedersen R, Fu J, Wang Z, Fan G, Sadayappan S, Wang Y, Pauklin S, Huang F, Huang W, Jiang L, 2022
- 3D-Epigenomic Regulation of Gene Transcription in Hepatocellular Carcinoma Cells, Feng Y, Wang P, Cai L, Zhan M, He F, Wang J, Li Y, Gega E, Li S, Zhang W, Zhao W, Xin Y, He X, Chen X, Ruan Y, Lu L, 2022
- 3D chromatin architecture and transcription regulation in cancer, Deng S, Feng Y, Pauklin S, 2022
- EZH2 and JARID2 shift their binding profiles on RNAs and DNAs between hepatocellular carcinoma and normal liver cells, Wen Z, He K, Zhan M, Li Y, Liu F, He X, Wei Y, Zhao W, Zhang Y, Xue Y, Xia Y, Lian Y, Xia Z, Xin Y, Wu Y, Duan X, Xiao J, Shen F, Feng Y, Xiang G, Lu L, 2022
- Mitochondrial nucleoid in cardiac homeostasis: bidirectional signaling of mitochondria and nucleus in cardiac diseases, Feng Y, Huang W, Paul C, Liu X, Sadayappan S, Wang Y, Pauklin S, 2021
- Targeting Epigenetic Mechanisms in Vascular Aging, Lin Z, Ding Q, Li X, Feng Y, He H, Huang C, Zhu Y, 2022
- Integrative epigenomic profiling reveal AP-1 is a key regulator in intrahepatic cholangiocarcinoma, He K, Feng Y, An S, Liu F, Xiang G, 2021
- In Situ Chromatin Interaction Analysis Using Paired‐End Tag Sequencing, Wang P, Feng Y, Zhu K, Chai H, Chang YT, Liu X, Shen C, Gega E, Li B, Kim M, Ruan X, Ruan Y, 2021
- Subcellular Localization of miRNAs and Implications in Cellular Homeostasis, Jie M, Feng T, Huang W, Zhang M, Feng Y, Jiang H, Wen Z, 2021
- Phosphodiesterase-5 inhibitors in Men with Stable Coronary Artery Disease, Wen Z, Feng Y, Jiang L, 2021
- PAF1 regulates the stemness of pancreatic cancer stem cells, Feng Y, Mouti M, Pauklin S, 2021
- Similar risk of hepatocellular carcinoma during long-term entecavir or tenofovir therapy in Caucasian patients with chronic hepatitis B, Wen Z, Feng Y, Yan X, 2021
- 3D chromatin architecture and epigenetic regulation in cancer stem cells, Feng Y, Liu X, Pauklin S, 2021
- ChIA-PIPE: A fully automated pipeline for comprehensive ChIA-PET data analysis and visualization, Lee B, Wang J, Cai L, Kim M, Namburi S, Tjong H, Feng Y, Wang P, Tang Z, Abbas A, Wei CL, Ruan Y, Li S, 2020
- Targeting TGFbeta Signalling in Cancer: Toward Context-Specific Strategies, French R, Feng Y, Pauklin S, 2020
- Two Sides of the Same Coin: The Roles of Transforming Growth Factor-beta in Colorectal Carcinogenesis, Feng Y, Pauklin S, 2020
- Demystifying Cancer Etiology via 3D Genome Mapping, Feng Y, Pauklin S, 2020
- Revisiting 3D chromatin architecture in cancer development and progression, Feng Y, Pauklin S, 2020
- Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential, Huang W, Liang J, Feng Y, Jia Z, Jiang L, Cai W, Paul C, Gu JG, Stambrook PJ, Millard RW, Zhu XL, Zhu P, Wang Y, 2018
- Loss of microRNA-128 promotes cardiomyocyte proliferation and heart regeneration, Huang W, Feng Y, Liang J, Yu H, Wang C, Wang B, Wang M, Jiang L, Meng W, Cai W, Medvedovic M, Chen J, Paul C, Davidson WS, Sadayappan S, Stamb
Awards
- National Talent Title
- Guangdong Outstanding Youth
- Shenzhen Talent Title
- Gordon Research Conference Invited Speaker (2023)
- ISHR Richard J Bing Young Investigator Award Finalist (2022)
- University of Oxford Botnar Research Centre Best Poster Award (2021)
- University of Oxford Clarendon Fund (Clarendon Scholar) (2019-2022)
- Winkler Oxford Award in Medicine or Psychology (2019)
- ISHR Global Conference Travel Award (2010 Japan, 2013 USA, 2016 Argentina)
- ISHR China Chapter Young Excellent Paper First Prize (2012, 2014)