2004-08 to 2006-06 Master's: University of Colorado School of Medicine
2000-09 to 2004-06 Bachelor's: Peking University
2018-10 to Present - Wuhan Institute of Virology, CAS - Director
2015-12 to 2018-10 - Wuhan Institute of Virology, CAS - Deputy Director
2014-12 to 2015-12 - Wuhan Institute of Virology, CAS - Assistant Director
2014-07 to 2015-06 - Wuchang District Health and Family Planning Commission - Deputy Director
2012-03 to Present - Wuhan Institute of Virology, CAS - Researcher
2010-11 to 2012-02 - Wuhan University School of Life Sciences - Associate Professor
2006-08 to 2010-10 - Wuhan University School of Life Sciences - Lecturer
16th China Young Female Scientist Award (2020): National Level
National Ten Thousand Talents Program for Young and Middle-aged Leading Talents in Scientific and Technological Innovation (2019): National Level
12th Outstanding Youth of the Chinese Academy of Sciences (2017): Institute Level
Expert Enjoying Special Government Allowance (2016): National Level
Ministry of Education Natural Science Award, First Prize (2015): Ministerial Level
National Natural Science Award, Second Prize (2015): National Level
National Hundred, Thousand, and Ten Thousand Talent Project 'Outstanding Contribution Young and Middle-aged Expert' (2015): National Level
Hubei Youth May Fourth Medal (2015): Provincial Level
National Outstanding Youth Science Fund (2014): National Level
First Batch of Young Top Talents in the Central Organization Department's Ten Thousand Talents Program (2013): Ministerial Level
Outstanding Scientific and Technological Worker of Wuhan (2013): Municipal Level
Wuhan Youth Science and Technology Award (2012): Municipal Level
Luojia Young Scholar of Wuhan University (2012): Institutional Level
Chinese Immunology Youth Scholar Award (2010): Other
Second Prize in Wuhan University Young Teacher Teaching Competition (2010): Institutional Level
Advanced Individual in Student Work of Wuhan University (2008): Institutional Level
Research
Virus-host interaction mechanisms Antiviral immune response and viral immune evasion
LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus, Yan Yi Wang, 2024
African Swine Fever Virus Cysteine Protease pS273R Inhibits Type I Interferon Signaling by Mediating STAT2 Degradation, Yan Yi Wang, 2023
Transcription-independent regulation of STING activation and innate immune responses by IRF8 in monocytes, Yan Yi Wang, 2022
African swine fever virus I267L acts as an important virulence factor by inhibiting RNA polymerase III-RIG-I-mediated innate immunity, Yan Yi Wang, 2022
Herpes simplex virus protein UL56 inhibits cGAS-Mediated DNA sensing to evade antiviral immunity, Yan Yi Wang, 2022
SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5, Yan Yi Wang, 2021
FAM177A1 Inhibits IL-1β–Induced Signaling by Impairing TRAF6–Ubc13 Association, Yan Yi Wang, 2021
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response, Yan Yi Wang, 2021
Capillary electrophoresis based on nucleic acid analysis for diagnosing inherited diseases, Yan Yi Wang, 2021
Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes, Yan Yi Wang, 2020
Infection with novel coronavirus(SARS-CoV-2)causes pneumonia in Rhesus macaques, Yan Yi Wang, 2020
SRP54NegativelyRegulatesIFN-BetaProductionandAntiviralResponsebyTargetingRIG-IandMDA5, Yan Yi Wang, 2020
Human Cytomegalovirus Protein UL94 Targets MITA to Evade Antiviral Immune Response., Yan Yi Wang, 2020
Histone deacetylase 4 inhibits NF-kappa B activation by facilitating I kappa B alpha sumoylation, Yan Yi Wang, 2020
RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization, Yan Yi Wang, 2020
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response, Yan Yi Wang, 2020
Human Cytomegalovirus Protein UL94 Targets MITA to Evade the Antiviral Immune Response, Yan Yi Wang, 2020
USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA, Yan Yi Wang, 2020
Temporal profiling of plasma cytokines, chemokines and growth factors from mild, severe and fatal COVID-19 patients, Yan Yi Wang, 2020
Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response, Yan Yi Wang, 2020
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication, Yan Yi Wang, 2020
YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking, Yan Yi Wang, 2019
Host HDAC4 regulates the antiviral response by inhibiting the phosphorylation of IRF3, Yan Yi Wang, 2019
FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis, Yan Yi Wang, 2019
RNF152 positively regulatesTLR/IL signaling by enhancing signaling MyD88 oligomerizationo, Yan Yi Wang, 2019
Human cytomegalovirus protein UL42 antagonizes cGAS/MITA-mediated innate antiviral response., Yan Yi Wang, 2019
Human Cytomegalovirus DNA Polymerase 1 Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3- and NF-kB-mediated transcription., Yan Yi Wang, 2019
Human Cytomegalovirus DNA Polymerase Subunit UL44 Antagonizes Antiviral Immune Responses by Suppressing IRF3-and NF-kappa B-Mediated Transcription, Yan Yi Wang, 2019
Human Cytomegalovirus Protein UL31 Inhiibits DNA Sensing of cGAS to Mediate Immune Evasion, Yan Yi Wang, 2018
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis, Yan Yi Wang, 2018
The Regulation of cGAS, Yan Yi Wang, 2018
PLA1A Participates in the Antiviral Innate Immune Response by Facilitating the Recruitment of TANK-Binding Kinase 1 to Mitochondria, Yan Yi Wang, 2018
WDR5 Facilitates Human Cytomegalovirus Replication by Promoting Capsid Nuclear Egress, Yan Yi Wang, 2018
Human Cytomegalovirus Protein UL31 Inhibits DNA Sensing of cGAS to Mediate Imm