Professor | Wang Jie | Asia Growth Partners

Name	Wang Jie
Contact Information	wang_jie01@gibh.ac.cn
Language ability	Chinese, English
Province	Guangdong

Name

Wang Jie

Contact Information

wang_jie01@gibh.ac.cn

Language ability

Chinese, English

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2009-09 to 2014-07: Ph.D. in Bioinformatics, Shanghai Institute of Life Sciences, Chinese Academy of Sciences 2005-09 to 2009-07: Bachelor's degree, Chongqing University
Work Experience	2020-12 to Present: Researcher, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences 2014-12 to 2020-11: Postdoctoral Fellow, Johns Hopkins University
Awards	Wilmer Distinguished Postdoctoral Award, First Prize, 2018

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2009-09 to 2014-07: Ph.D. in Bioinformatics, Shanghai Institute of Life Sciences, Chinese Academy of Sciences
2005-09 to 2009-07: Bachelor's degree, Chongqing University

Work Experience

2020-12 to Present: Researcher, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences
2014-12 to 2020-11: Postdoctoral Fellow, Johns Hopkins University

Awards

Wilmer Distinguished Postdoctoral Award, First Prize, 2018

Areas of Focus	Epigenomics and Bioinformatics of Organ Regeneration
Publications	DNA hypermethylation modification promotes the development of hepatocellular carcinoma by depressing the tumor suppressor gene ZNF334, Corresponding Author, 2022 IReNA: Integrated regulatory network analysis of single-cell transcriptomes and chromatin accessibility profiles, Corresponding Author, 2022 LRLoop: a method to predict feedback loops in cell-cell communication, 5th Author, 2022 Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1, 6th Author, 2021 Gene regulatory networks controlling vertebrate retinal regeneration, 2nd Author, 2020 Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways, 5th Author, 2020 Investigating cone photoreceptor development using patient-derived NRL null retinal organoids, 3rd Author, 2020 Comparative transcriptomic and epigenomic analysis identifies regulators of neurogenic competence in retinal Muller glia, 3rd Author, 2018 Muller cell transcriptional unit to regulate stress induced LIF expression, 4th Author, 2018 Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina, 5th Author, 2018 Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes, 4th Author, 2018 ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration, 1st Author, 2018 Heterozygous IDH1 R132H created by 'single base editing' inhibits human astroglial cell growth by downregulating YAP, 2nd Author, 2018 The Prediction of Clinical Outcome in Hepatocellular Carcinoma Based on a Six-Gene Metastasis Signature, Corresponding Author, 2017 ScaPD: a database for human scaffold proteins, 3rd Author, 2017 Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes, 1st Author, 2016 Long Noncoding RNA DANCR Increases Stemness Features of Hepatocellular Carcinoma by Derepression of CTNNB1, 2nd Author, 2016 Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and IncRNA expression profiles, 2nd Author, 2015 Antisense long non-coding RNA PCNA-AS1 promotes tumor growth by regulating proliferating cell nuclear antigen in hepatocellular carcinoma, 3rd Author, 2014 Synchronization of cytoplasm and transferred mitochondrial ribosomal protein gene expression in land plants is linked to telo-box motif enrichment, 1st Author, 2011

Areas of Focus

Epigenomics and Bioinformatics of Organ Regeneration

Publications

DNA hypermethylation modification promotes the development of hepatocellular carcinoma by depressing the tumor suppressor gene ZNF334, Corresponding Author, 2022
IReNA: Integrated regulatory network analysis of single-cell transcriptomes and chromatin accessibility profiles, Corresponding Author, 2022
LRLoop: a method to predict feedback loops in cell-cell communication, 5th Author, 2022
Mutant IDH1 promotes phagocytic function of microglia/macrophages in gliomas by downregulating ICAM1, 6th Author, 2021
Gene regulatory networks controlling vertebrate retinal regeneration, 2nd Author, 2020
Retinal pigment epithelium transcriptome analysis in chronic smoking reveals a suppressed innate immune response and activation of differentiation pathways, 5th Author, 2020
Investigating cone photoreceptor development using patient-derived NRL null retinal organoids, 3rd Author, 2020
Comparative transcriptomic and epigenomic analysis identifies regulators of neurogenic competence in retinal Muller glia, 3rd Author, 2018
Muller cell transcriptional unit to regulate stress induced LIF expression, 4th Author, 2018
Transcriptomics analysis of Muller glia in response to different damage paradigms in the adult zebrafish retina, 5th Author, 2018
Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes, 4th Author, 2018
ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration, 1st Author, 2018
Heterozygous IDH1 R132H created by 'single base editing' inhibits human astroglial cell growth by downregulating YAP, 2nd Author, 2018
The Prediction of Clinical Outcome in Hepatocellular Carcinoma Based on a Six-Gene Metastasis Signature, Corresponding Author, 2017
ScaPD: a database for human scaffold proteins, 3rd Author, 2017
Single-Cell Co-expression Analysis Reveals Distinct Functional Modules, Co-regulation Mechanisms and Clinical Outcomes, 1st Author, 2016
Long Noncoding RNA DANCR Increases Stemness Features of Hepatocellular Carcinoma by Derepression of CTNNB1, 2nd Author, 2016
Berberine ameliorates nonalcoholic fatty liver disease by a global modulation of hepatic mRNA and IncRNA expression profiles, 2nd Author, 2015
Antisense long non-coding RNA PCNA-AS1 promotes tumor growth by regulating proliferating cell nuclear antigen in hepatocellular carcinoma, 3rd Author, 2014
Synchronization of cytoplasm and transferred mitochondrial ribosomal protein gene expression in land plants is linked to telo-box motif enrichment, 1st Author, 2011

Epigenomics Bioinformatics Organ Regeneration Single-Cell Sequencing High-Throughput Technologies Statistical Modeling Machine Learning Network Reconstruction Epigenetic Regulation Mathematical Modeling

Huang Jie - Southern University of Science and Technology

Shenying Fang - Southern University of Science and Technology

Jingtao Guo - University of Chinese Academy of Sciences

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