Professor | Zhisheng Xu | Asia Growth Partners

Name	Zhisheng Xu
Contact Information	zsxu@wh.iov.cn
Language ability	Chinese, English
Province	Hubei

Name

Zhisheng Xu

Contact Information

zsxu@wh.iov.cn

Language ability

Chinese, English

Province

Hubei

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2012-09--2015-06 PhD: Wuhan University 2006-09--2009-06 Master's: Wuhan University 2002-09--2006-06 Bachelor's: Wuhan University
Work Experience	2021-03~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher 2020-09~2021-02 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher 2015-07~2020-08 - Guangzhou Women and Children's Medical Center/Wuhan Institute of Virology, Chinese Academy of Sciences - Postdoctoral Researcher 2012-09~2015-06 - Wuhan University - PhD 2009-07~2011-06 - School of Life Sciences, Wuhan University - Research Assistant 2006-09~2009-06 - Wuhan University - Master's 2002-09~2006-06 - Wuhan University - Bachelor's

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2012-09--2015-06 PhD: Wuhan University
2006-09--2009-06 Master's: Wuhan University
2002-09--2006-06 Bachelor's: Wuhan University

Work Experience

2021-03~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Associate Researcher
2020-09~2021-02 - Wuhan Institute of Virology, Chinese Academy of Sciences - Assistant Researcher
2015-07~2020-08 - Guangzhou Women and Children's Medical Center/Wuhan Institute of Virology, Chinese Academy of Sciences - Postdoctoral Researcher
2012-09~2015-06 - Wuhan University - PhD
2009-07~2011-06 - School of Life Sciences, Wuhan University - Research Assistant
2006-09~2009-06 - Wuhan University - Master's
2002-09~2006-06 - Wuhan University - Bachelor's

Areas of Focus	Inflammatory Response Host-Virus Interaction
Publications	LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus, First Author, 2024 SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5, Fifth Author, 2021 FAM177A1 Inhibits IL-1β-Induced Signaling by Impairing TRAF6-Ubc13 Association, Eleventh Author, 2021 SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response, Sixth Author, 2021 SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication, Third Author, 2021 RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization, Second Author, 2020 Temporal profiling of plasma cytokines, chemokines and growth factors from mild, severe and fatal COVID-19 patients, First Author, 2020 USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA, Third Author, 2020 Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response, Eleventh Author, 2020 YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking, Third Author, 2019 FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis, First Author, 2019 TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis, Second Author, 2018 March3 attenuates il-1 beta-triggered inflammation by mediating k48-linked polyubiquitination and degradation of il-1ri, Eleventh Author, 2018 PASD1 promotes STAT3 activity and tumor growth by inhibiting TC45-mediated dephosphorylation of STAT3 in the nucleus, First Author, 2016 Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-beta signaling pathway, Third Author, 2016 MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes, Third Author, 2016 High-level Expression of Silkworm Antimicrobial Peptide and Its Anti-infection to BmNPV, Sixth Author, 2006

Areas of Focus

Inflammatory Response
Host-Virus Interaction

Publications

LDLR is an entry receptor for Crimean-Congo hemorrhagic fever virus, First Author, 2024
SRP54 Negatively Regulates IFN-Beta Production and Antiviral Response by Targeting RIG-I and MDA5, Fifth Author, 2021
FAM177A1 Inhibits IL-1β-Induced Signaling by Impairing TRAF6-Ubc13 Association, Eleventh Author, 2021
SARS-CoV-2 membrane glycoprotein M antagonizes the MAVS-mediated innate antiviral response, Sixth Author, 2021
SARS-CoV-2 nucleocapsid protein impairs stress granule formation to promote viral replication, Third Author, 2021
RNF152 positively regulates TLR/IL-1R signaling by enhancing MyD88 oligomerization, Second Author, 2020
Temporal profiling of plasma cytokines, chemokines and growth factors from mild, severe and fatal COVID-19 patients, First Author, 2020
USP44 positively regulates innate immune response to DNA viruses through deubiquitinating MITA, Third Author, 2020
Ubiquitination of TLR3 by TRIM3 signals its ESCRT-mediated trafficking to the endolysosomes for innate antiviral response, Eleventh Author, 2020
YIPF5 Is Essential for Innate Immunity to DNA Virus and Facilitates COPII-Dependent STING Trafficking, Third Author, 2019
FAM64A positively regulates STAT3 activity to promote Th17 differentiation and colitis-associated carcinogenesis, First Author, 2019
TRIM27 mediates STAT3 activation at retromer-positive structures to promote colitis and colitis-associated carcinogenesis, Second Author, 2018
March3 attenuates il-1 beta-triggered inflammation by mediating k48-linked polyubiquitination and degradation of il-1ri, Eleventh Author, 2018
PASD1 promotes STAT3 activity and tumor growth by inhibiting TC45-mediated dephosphorylation of STAT3 in the nucleus, First Author, 2016
Foot-and-mouth disease virus non-structural protein 3A inhibits the interferon-beta signaling pathway, Third Author, 2016
MSX1 Modulates RLR-Mediated Innate Antiviral Signaling by Facilitating Assembly of TBK1-Associated Complexes, Third Author, 2016
High-level Expression of Silkworm Antimicrobial Peptide and Its Anti-infection to BmNPV, Sixth Author, 2006

Inflammation Immune Response Cytokines Chemokines Viral Infection Host-Pathogen Interaction Immune Signaling Pathogenesis Molecular Mechanisms Immune Regulation

Fengliang Liu - University of Chinese Academy of Sciences

Ju Qiu - University of Chinese Academy of Sciences

Qian Youcun - University of Chinese Academy of Sciences

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us