Professor | Xinglou Yang | Asia Growth Partners

Name	Xinglou Yang
Contact Information	yangxinglou@mail.kiz.ac.cn
Language ability	Chinese, English
Province	Yunnan

Name

Xinglou Yang

Contact Information

yangxinglou@mail.kiz.ac.cn

Language ability

Chinese, English

Province

Yunnan

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2017-09--2018-09 Visiting Scholar: Duke-NUS Medical School 2008-09--2014-01 PhD: University of Chinese Academy of Sciences
Work Experience	2016-09~Present - Chinese Academy of Sciences Wuhan Institute of Virology - Associate Researcher 2014-01~2016-09 - Chinese Academy of Sciences Wuhan Institute of Virology - Assistant Researcher
Awards	2018: Research on Important Viruses Carried by Chinese Bats, Second Prize, National Level 2017: Research on Important Viruses Carried by Chinese Bats, First Prize, Provincial Level 2014: Excellent Academic Paper in Natural Science of Hubei Province, Special Prize, Provincial Level

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2017-09--2018-09 Visiting Scholar: Duke-NUS Medical School
2008-09--2014-01 PhD: University of Chinese Academy of Sciences

Work Experience

2016-09~Present - Chinese Academy of Sciences Wuhan Institute of Virology - Associate Researcher
2014-01~2016-09 - Chinese Academy of Sciences Wuhan Institute of Virology - Assistant Researcher

Awards

2018: Research on Important Viruses Carried by Chinese Bats, Second Prize, National Level
2017: Research on Important Viruses Carried by Chinese Bats, First Prize, Provincial Level
2014: Excellent Academic Paper in Natural Science of Hubei Province, Special Prize, Provincial Level

Areas of Focus	Pathogeny and Molecular Epidemiology of Emerging Animal Viruses
Publications	Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages, Harold Marcotte, Yunlong Cao, Fanglei Zuo, Luca Simonelli, Jos Camilla Sammartino, Mattia Pedotti, Rui Sun, Irene Cassaniti, Marie Hagbom, Antonio Piralla, Jinxuan Yang, Likun Du, Elena Percivalle, Federico Bertoglio, Maren Schubert, Hassan Abolhassani, Natalia Sherina, Concetta Guerra, Stephan Borte, Nima Rezaei, Makiko KumagaiBraesch, Yintong Xue, Chen Su, Qihong Yan, Ping He, Caroline Grnwall, Lars Klareskog, Luigi Calzolai, Andrea Cavalli, Qiao Wang, Davide F Robbiani, Michael Hust, Zhengli Shi, Liqiang Feng, Lennart Svensson, Ling Chen, Linlin Bao, Fausto Baldanti, Junyu Xiao, Chuan Qin, Lennart Hammarstrm, Xinglou Yang, Luca Varani, Xiaoliang Sunney Xie, Qiang PanHammarstrm, 2024 Substantial viral diversity in bats and rodents from East Africa: insights into evolution, recombination, and cocirculation, 杨兴娄, 2024 Pangolin HKU4-related coronaviruses found in greater bamboo bats from southern China, Min Guo, Kai Zhao, Xingwen Peng, Xiangyang He, Jin Deng, Bo Wang, Xinglou Yang, Libiao Zhang, 2023 A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry, Jing Chen, Xinglou Yang, Haorui Si, Qianchun Gong, Tengcheng Que, Jing Li, Yang Li, Chunguang Wu, Wei Zhang, Ying Chen, Yun Luo, Yan Zhu, Bei Li, Dongsheng Luo, Ben Hu, Haofeng Lin, Rendi Jiang, Tingting Jiang, Qian Li, Meiqin Liu, Shizhe Xie, Jia Su, Xiaoshuang Zheng, Ang Li, Yulin Yao, Yong Yang, Panyu Chen, Aiqiong Wu, Meihong He, Xinhua Lin, Yigang Tong, Yanling Hu, ZhengLi Shi, Peng Zhou, 2023 Direct infection of SARS-CoV-2 in human iPSC-derived 3D cardiac organoids recapitulates COVID-19 myocarditis, Weijie Wang, Jinxuan Yang, Pinfang Kang, Jinsong Bai, Xiaoli Feng, Liuqi Huang, Yiming Zhang, Yuechun Wu, Bi Tang, Hongju Wang, JianJie Jiang, Minghua Li, Bing Zhao, Xinglou Yang, 2023 Multiplication of defective Ebola virus in a complementary permissive cell line, Tong, XianKun, Li, Heng, Yang, Li, Xie, ShiZhe, Xie, Sha, Gong, Ying, Peng, Cheng, Gao, XiaoXiao, Shi, ZhengLi, Yang, XingLou, Zuo, JianPing, 2023 A SARS-CoV-2-Related Virus from Malayan Pangolin Causes Lung Infection without Severe Disease in Human ACE2-Transgenic Mice, Liu, MeiQin, Lin, HaoFeng, Li, Jing, Chen, Ying, Luo, Yun, Zhang, Wei, Hu, Ben, Tian, FengJuan, Hu, YunJia, Liu, YuJie, Jiang, RenDi, Gong, QianChun, Li, Ang, Guo, ZiShuo, Li, Bei, Yang, XingLou, Tong, YiGang, Shi, ZhengLi, 2023 Pteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptor, Tan, Chee Wah, Gamage, Akshamal M, Yap, Wee Chee, Tang, Leon Jia Wei, Sun, Yuan, Yang, XingLou, Pyke, Alyssa, Chua, Kaw Bing, Wang, LinFa, 2023 Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses, Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Mei Liu, XingLou Yang, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, ZhengLi Shi, Jinghe Huang, 2022 Chirohepevirus from Bats: Insights into Hepatitis E Virus Diversity and Evolution, Bo Wang, XingLou Yang, 2022 ACE2-independent infection of T lymphocytes by SARS-CoV-2, XuRui Shen, Rong Geng, Qian Li, Ying Chen, ShuFen Li, Qi Wang, Juan Min, Yong Yang, Bei Li, RenDi Jiang, Xi Wang, XiaoShuang Zheng, Yan Zhu, JingKun Jia, XingLou Yang, MeiQin Liu, QianChun Gong, YuLan Zhang, ZhenQiong Guan, HuiLing Li, ZhenHua Zheng, ZhengLi Shi, HuiLan Zhang, Ke Peng, Peng Zhou, 2022 Inactivated SARS-CoV-2 Vaccine Shows Cross-Protection against Bat SARS-Related Coronaviruses in Human ACE2 Transgenic Mice, MeiQin Liu, RenDi Jiang, Jing Guo, Ying Chen, DongSheng Yang, Xi Wang, HaoFeng Lin, Ang Li, Bei Li, Ben Hu, ZeJun Wang, XingLou Yang, ZhengLi Shi, Tom Gallagher, 2022 Fish ACE2 is not susceptible to SARS-CoV-2, ShiZhe Xie, MeiQin Liu, RenDi Jiang, HaoFeng Lin, Wei Zhang, Bei Li, Jia Su, Fei Ke, QiYa Zhang, ZhengLi Shi, XingLou Yang, 2022 Bat virome research: the past, the present and the future, Tan, Chee Wah, Yang, Xinglou, Anderson, Danielle E, Wang, LinFa, 2021 Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates, Yao, YanFeng, Wang, ZeJun, Jiang, RenDi, Hu, Xue, Zhang, HuaJun, Zhou, YiWu, Gao, Ge, Chen, Ying, Peng, Yun, Liu, MeiQin, Zhang, YaNan, Min, Juan, Lu, Jia, Gao, XiaoXiao, Guo, Jing, Peng, Cheng, Shen, XuRui, Li, Qian, Zhao, Kai, Yang, Lian, Wan, Xin, Zhang, Bo, Wang, WenHui, Wu, Jia, Zhou, Peng, Yang, XingLou, Shen, Shuo, Shan, Chao, Yuan, ZhiMing, Shi, ZhengLi, 2021 Stability of SARS-CoV-2 on the Surfaces of Three Meats in the Setting That Simulates the Cold Chain Transportation, Feng, XiaoLi, Li, Bei, Lin, HaoFeng, Zheng, HongYi, Tian, RenRong, Luo, RongHua, Liu, MeiQin, Jiang, RenDi, Zheng, YongTang, Shi, ZhengLi, Bi, YuHai, Yang, XingLou, 2021 Antibody-Dependent Enhancement of SARS-CoV-2 Infection of Human Immune Cells: In Vitro Assessment Provides Insight in COVID-19 Pathogenesis, Shen, XuRui, Li, Qian, Li, HuiLing, Wang, Xi, Wang, Qi, Zheng, XiaoShuang, Geng, Rong, Zhang, YuLan, Li, Bei, Jiang, RenDi, Liu, MeiQin, Zhu, Yan, Zhang, Wei, Yang, XingLou, Peng, Ke, Zhou, Peng, 2021 Identification of ZDHHC17 as a Potential Drug Target for Swine Acute Diarrhea Syndrome Coronavirus Infection, Yun Luo, Chee Wah Tan, ShiZhe Xie, Ying Chen, YuLin Yao, Kai Zhao, Yan Zhu, Qi Wang, MeiQin Liu, XingLou Yang, LinFa Wang, ZhengLi Shi, Peter Palese, 2021 The SARS-CoV-2 subgenome landscape and its novel regulatory features, Wang, Dehe, Jiang, Ao, Feng, Jiangpeng, Li, Guangnan, Guo, Dong, Sajid, Muhammad, Wu, Kai, Zhang, Qiuhan, Ponty, Yann, Will, Sebastian, Liu, Feiyan, Yu, Xinghai, Li, Shaopeng, Liu, Qianyun, Yang, XingLou, Guo, Ming, Li, Xingqiao, Chen, Mingzhou, Shi, ZhengLi, Lan, Ke, Chen, Yu, Zhou, Yu, 2021 Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells, Chen, Ying, Liu, MeiQin, Luo, Yun, Jiang, RenDi, Si, HaoRui, Zhu, Yan, Li, Bei, Shen, XuRui, Lin, HaoFeng, Zhao, Kai, Hu, Ben, Shi, ZhengLi, Yang, XingLou, 2021 2020 taxonomic update for phylumNegarnaviricota(Riboviria:Orthornavirae), including the large ordersBunyaviralesandMononegavirales, Kuhn, Jens H, Adkins, Scott, Alioto, Daniela, Alkhovsky, Sergey V, Amarasinghe, Gaya K, Anthony, Simon J, AvsicZupanc, Tatjana, Ayllon, Maria A, Bahl, Justin, BalkemaBuschmann, Anne, Ballinger, Matthew J, Bartonicka, Tomas, Basler, Christopher, Bavari, Sina, Beer, Martin, Bente, Dennis A, Bergeron, Eric, Bird, Brian H, Blair, Carol, Blasdell, Kim R, Bradfute, Steven B, Breyta, Rachel, Briese, Thomas, Brown, Paul A, Buchholz, Ursula J, Buchmeier, Michael J, Bukreyev, Alexander, Burt, Felicity, Buzkan, Nihal, Calisher, Charles H, Cao, Mengji, Casas, Inmaculada, Chamberlain, John, Chandran, Kartik, Charrel, Remi N, Chen, Biao, Chiumenti, Michela, Choi, IlRyong, Clegg, J Christopher S, Crozier, Ian, da Graca, John V, Dal Bo, Elena, Davila, Alberto M R, de la Torre, Juan Carlos, de Lamballerie, Xavier, de Swart, Rik L, Di Bello, Patrick L, Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G, Digiaro, Michele, Dolja, Valerian V, Dolnik, Olga, Drebot, Michael A, Drexler, Jan Felix, Duer

Areas of Focus

Pathogeny and Molecular Epidemiology of Emerging Animal Viruses

Publications

Conversion of monoclonal IgG to dimeric and secretory IgA restores neutralizing ability and prevents infection of Omicron lineages, Harold Marcotte, Yunlong Cao, Fanglei Zuo, Luca Simonelli, Jos Camilla Sammartino, Mattia Pedotti, Rui Sun, Irene Cassaniti, Marie Hagbom, Antonio Piralla, Jinxuan Yang, Likun Du, Elena Percivalle, Federico Bertoglio, Maren Schubert, Hassan Abolhassani, Natalia Sherina, Concetta Guerra, Stephan Borte, Nima Rezaei, Makiko KumagaiBraesch, Yintong Xue, Chen Su, Qihong Yan, Ping He, Caroline Grnwall, Lars Klareskog, Luigi Calzolai, Andrea Cavalli, Qiao Wang, Davide F Robbiani, Michael Hust, Zhengli Shi, Liqiang Feng, Lennart Svensson, Ling Chen, Linlin Bao, Fausto Baldanti, Junyu Xiao, Chuan Qin, Lennart Hammarstrm, Xinglou Yang, Luca Varani, Xiaoliang Sunney Xie, Qiang PanHammarstrm, 2024
Substantial viral diversity in bats and rodents from East Africa: insights into evolution, recombination, and cocirculation, 杨兴娄, 2024
Pangolin HKU4-related coronaviruses found in greater bamboo bats from southern China, Min Guo, Kai Zhao, Xingwen Peng, Xiangyang He, Jin Deng, Bo Wang, Xinglou Yang, Libiao Zhang, 2023
A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry, Jing Chen, Xinglou Yang, Haorui Si, Qianchun Gong, Tengcheng Que, Jing Li, Yang Li, Chunguang Wu, Wei Zhang, Ying Chen, Yun Luo, Yan Zhu, Bei Li, Dongsheng Luo, Ben Hu, Haofeng Lin, Rendi Jiang, Tingting Jiang, Qian Li, Meiqin Liu, Shizhe Xie, Jia Su, Xiaoshuang Zheng, Ang Li, Yulin Yao, Yong Yang, Panyu Chen, Aiqiong Wu, Meihong He, Xinhua Lin, Yigang Tong, Yanling Hu, ZhengLi Shi, Peng Zhou, 2023
Direct infection of SARS-CoV-2 in human iPSC-derived 3D cardiac organoids recapitulates COVID-19 myocarditis, Weijie Wang, Jinxuan Yang, Pinfang Kang, Jinsong Bai, Xiaoli Feng, Liuqi Huang, Yiming Zhang, Yuechun Wu, Bi Tang, Hongju Wang, JianJie Jiang, Minghua Li, Bing Zhao, Xinglou Yang, 2023
Multiplication of defective Ebola virus in a complementary permissive cell line, Tong, XianKun, Li, Heng, Yang, Li, Xie, ShiZhe, Xie, Sha, Gong, Ying, Peng, Cheng, Gao, XiaoXiao, Shi, ZhengLi, Yang, XingLou, Zuo, JianPing, 2023
A SARS-CoV-2-Related Virus from Malayan Pangolin Causes Lung Infection without Severe Disease in Human ACE2-Transgenic Mice, Liu, MeiQin, Lin, HaoFeng, Li, Jing, Chen, Ying, Luo, Yun, Zhang, Wei, Hu, Ben, Tian, FengJuan, Hu, YunJia, Liu, YuJie, Jiang, RenDi, Gong, QianChun, Li, Ang, Guo, ZiShuo, Li, Bei, Yang, XingLou, Tong, YiGang, Shi, ZhengLi, 2023
Pteropine orthoreoviruses use cell surface heparan sulphate as an attachment receptor, Tan, Chee Wah, Gamage, Akshamal M, Yap, Wee Chee, Tang, Leon Jia Wei, Sun, Yuan, Yang, XingLou, Pyke, Alyssa, Chua, Kaw Bing, Wang, LinFa, 2023
Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses, Yingdan Wang, Meiqin Liu, Yaping Shen, Yunping Ma, Xiang Li, Yuanyuan Zhang, Mei Liu, XingLou Yang, Jun Chen, Renhong Yan, Die Luan, Yanqun Wang, Ying Chen, Qimin Wang, Haofeng Lin, Yaning Li, Kaiyue Wu, Tongyu Zhu, Jincun Zhao, Hongzhou Lu, Yumei Wen, Shibo Jiang, Fan Wu, Qiang Zhou, ZhengLi Shi, Jinghe Huang, 2022
Chirohepevirus from Bats: Insights into Hepatitis E Virus Diversity and Evolution, Bo Wang, XingLou Yang, 2022
ACE2-independent infection of T lymphocytes by SARS-CoV-2, XuRui Shen, Rong Geng, Qian Li, Ying Chen, ShuFen Li, Qi Wang, Juan Min, Yong Yang, Bei Li, RenDi Jiang, Xi Wang, XiaoShuang Zheng, Yan Zhu, JingKun Jia, XingLou Yang, MeiQin Liu, QianChun Gong, YuLan Zhang, ZhenQiong Guan, HuiLing Li, ZhenHua Zheng, ZhengLi Shi, HuiLan Zhang, Ke Peng, Peng Zhou, 2022
Inactivated SARS-CoV-2 Vaccine Shows Cross-Protection against Bat SARS-Related Coronaviruses in Human ACE2 Transgenic Mice, MeiQin Liu, RenDi Jiang, Jing Guo, Ying Chen, DongSheng Yang, Xi Wang, HaoFeng Lin, Ang Li, Bei Li, Ben Hu, ZeJun Wang, XingLou Yang, ZhengLi Shi, Tom Gallagher, 2022
Fish ACE2 is not susceptible to SARS-CoV-2, ShiZhe Xie, MeiQin Liu, RenDi Jiang, HaoFeng Lin, Wei Zhang, Bei Li, Jia Su, Fei Ke, QiYa Zhang, ZhengLi Shi, XingLou Yang, 2022
Bat virome research: the past, the present and the future, Tan, Chee Wah, Yang, Xinglou, Anderson, Danielle E, Wang, LinFa, 2021
Protective Efficacy of Inactivated Vaccine against SARS-CoV-2 Infection in Mice and Non-Human Primates, Yao, YanFeng, Wang, ZeJun, Jiang, RenDi, Hu, Xue, Zhang, HuaJun, Zhou, YiWu, Gao, Ge, Chen, Ying, Peng, Yun, Liu, MeiQin, Zhang, YaNan, Min, Juan, Lu, Jia, Gao, XiaoXiao, Guo, Jing, Peng, Cheng, Shen, XuRui, Li, Qian, Zhao, Kai, Yang, Lian, Wan, Xin, Zhang, Bo, Wang, WenHui, Wu, Jia, Zhou, Peng, Yang, XingLou, Shen, Shuo, Shan, Chao, Yuan, ZhiMing, Shi, ZhengLi, 2021
Stability of SARS-CoV-2 on the Surfaces of Three Meats in the Setting That Simulates the Cold Chain Transportation, Feng, XiaoLi, Li, Bei, Lin, HaoFeng, Zheng, HongYi, Tian, RenRong, Luo, RongHua, Liu, MeiQin, Jiang, RenDi, Zheng, YongTang, Shi, ZhengLi, Bi, YuHai, Yang, XingLou, 2021
Antibody-Dependent Enhancement of SARS-CoV-2 Infection of Human Immune Cells: In Vitro Assessment Provides Insight in COVID-19 Pathogenesis, Shen, XuRui, Li, Qian, Li, HuiLing, Wang, Xi, Wang, Qi, Zheng, XiaoShuang, Geng, Rong, Zhang, YuLan, Li, Bei, Jiang, RenDi, Liu, MeiQin, Zhu, Yan, Zhang, Wei, Yang, XingLou, Peng, Ke, Zhou, Peng, 2021
Identification of ZDHHC17 as a Potential Drug Target for Swine Acute Diarrhea Syndrome Coronavirus Infection, Yun Luo, Chee Wah Tan, ShiZhe Xie, Ying Chen, YuLin Yao, Kai Zhao, Yan Zhu, Qi Wang, MeiQin Liu, XingLou Yang, LinFa Wang, ZhengLi Shi, Peter Palese, 2021
The SARS-CoV-2 subgenome landscape and its novel regulatory features, Wang, Dehe, Jiang, Ao, Feng, Jiangpeng, Li, Guangnan, Guo, Dong, Sajid, Muhammad, Wu, Kai, Zhang, Qiuhan, Ponty, Yann, Will, Sebastian, Liu, Feiyan, Yu, Xinghai, Li, Shaopeng, Liu, Qianyun, Yang, XingLou, Guo, Ming, Li, Xingqiao, Chen, Mingzhou, Shi, ZhengLi, Lan, Ke, Chen, Yu, Zhou, Yu, 2021
Genetic Mutation of SARS-CoV-2 during Consecutive Passages in Permissive Cells, Chen, Ying, Liu, MeiQin, Luo, Yun, Jiang, RenDi, Si, HaoRui, Zhu, Yan, Li, Bei, Shen, XuRui, Lin, HaoFeng, Zhao, Kai, Hu, Ben, Shi, ZhengLi, Yang, XingLou, 2021
2020 taxonomic update for phylumNegarnaviricota(Riboviria:Orthornavirae), including the large ordersBunyaviralesandMononegavirales, Kuhn, Jens H, Adkins, Scott, Alioto, Daniela, Alkhovsky, Sergey V, Amarasinghe, Gaya K, Anthony, Simon J, AvsicZupanc, Tatjana, Ayllon, Maria A, Bahl, Justin, BalkemaBuschmann, Anne, Ballinger, Matthew J, Bartonicka, Tomas, Basler, Christopher, Bavari, Sina, Beer, Martin, Bente, Dennis A, Bergeron, Eric, Bird, Brian H, Blair, Carol, Blasdell, Kim R, Bradfute, Steven B, Breyta, Rachel, Briese, Thomas, Brown, Paul A, Buchholz, Ursula J, Buchmeier, Michael J, Bukreyev, Alexander, Burt, Felicity, Buzkan, Nihal, Calisher, Charles H, Cao, Mengji, Casas, Inmaculada, Chamberlain, John, Chandran, Kartik, Charrel, Remi N, Chen, Biao, Chiumenti, Michela, Choi, IlRyong, Clegg, J Christopher S, Crozier, Ian, da Graca, John V, Dal Bo, Elena, Davila, Alberto M R, de la Torre, Juan Carlos, de Lamballerie, Xavier, de Swart, Rik L, Di Bello, Patrick L, Di Paola, Nicholas, Di Serio, Francesco, Dietzgen, Ralf G, Digiaro, Michele, Dolja, Valerian V, Dolnik, Olga, Drebot, Michael A, Drexler, Jan Felix, Duer

Pathogeny Molecular Epidemiology Emerging Viruses Animal Viruses Bats Rodents Virus Evolution Virus Recombination Virus Circulation Zoonotic Viruses

Zhengli Shi - University of Chinese Academy of Sciences

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