Areas of Focus
- Cardiovascular diseases
- Integration of Chinese and Western medicine
Academic Background & Achievements
- Bachelor and Master of Medicine: Tianjin University of Traditional Chinese Medicine
- PhD in Molecular Hematology: Imperial College London
- Postdoctoral Researcher: Yale University School of Medicine
- National Outstanding Youth Fund recipient
- Lead on national key research and development projects
Publications
- Brazilin-Ce nanoparticles attenuate inflammation by de/anti-phosphorylation of IKKβ, Li S, Wang K, Jiang K, Xing D, Deng R, Xu Y, Ding Y, Guan H, Chen LL, Wang D, Chen Y, Bu W, Xiang Y, 2024
- A transient wave of Bhlhe41+ resident macrophages enables remodeling of the developing infarcted myocardium, Xu Y, Jiang K, Su F, Deng R, Cheng Z, Wang D, Yu Y, Xiang Y, 2023
- Structural repurposing of SGLT2 inhibitor empagliflozin for strengthening anti-heart failure activity with lower glycosuria, Xu Y, Zhang C, Jiang K, Yang X, Chen F, Cheng Z, Zhao J, Cheng J, Li X, Chen X, Zhou L, Duan H, Huang Y, Xiang Y, Li J, 2023
- Anti-inflammatory effect of Danhong injection through inhibition of GSDMD-mediated pyroptosis, Li Y, Tu Z, Chen F, Yang X, Deng R, Su F, Cheng Z, Li S, Ong SB, Wang D, Chen Y, Xiang Y, 2023
- Bone marrow-derived naïve B lymphocytes improve heart function after myocardial infarction: a novel cardioprotective mechanism for empagliflozin, Xu Y, Jiang K, Chen F, Qian J, Wang D, Wu Y, Zhou C, Yu Y, Chen K, Hwa J, Yang B, Wang H, Xiang Y, 2022
- Gasdermin D inhibition confers antineutrophil-mediated cardioprotection in acute myocardial infarction, Jiang K, Tu Z, Chen K, Xu Y, Chen F, Xu S, Shi T, Qian J, Shen L, Hwa J, Wang D, Xiang Y, 2022
- Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosis, Jiang K, Xu Y, Wang D, Chen F, Tu Z, Qian J, Xu S, Xu Y, Hwa J, Li J, Shang H, Xiang Y, 2022
- The prokaryotic Argonaute proteins enhance homology sequence-directed recombination in bacteria, Fu L, Xie C, Jin Z, Tu Z, Han L, Jin M, Xiang Y, Zhang A, 2019
- Diabetes Exacerbates Myocardial Ischemia/Reperfusion Injury by Down-Regulation of MicroRNA and Up-Regulation of O-GlcNAcylation, Wang D, Hu X, Lee SH, Chen F, Jiang K, Tu Z, Liu Z, Du J, Wang L, Yin C, Liao Y, Shang H, Martin KA, Herzog RI, Young LH, Qian L, Hwa J, Xiang Y, 2018
- Hyperglycemia repression of miR-24 coordinately upregulates endothelial cell expression and secretion of von Willebrand factor, Xiang Y, Cheng J, Wang D, Hu X, Xie Y, Stitham J, Atteya G, Du J, Tang WH, Lee SH, Leslie K, Spollett G, Liu Z, Herzog E, Herzog RI, Lu J, Martin KA, Hwa J, 2015
- Mechanism of von Willebrand factor scissile bond cleavage by a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13 (ADAMTS13), Xiang Y, de Groot R, Crawley JT, Lane DA, 2011
- Platelet activation, and antiplatelet targets and agents: current and novel strategies, Xiang YZ, Xia Y, Gao XM, Shang HC, Kang LY, Zhang BL, 2008
Awards
- ISTH Young Investigators Award
- NSTH Science Prize
- Imperial Rector’s Award
