Professor | Bo Zhang | Asia Growth Partners

Name	Bo Zhang
Contact Information	zhangbo@wh.iov.cn
Language ability	Chinese, German, English
Province	Hubei

Name

Bo Zhang

Contact Information

zhangbo@wh.iov.cn

Language ability

Chinese, German, English

Province

Hubei

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2002-06--2005-11 PhD: University of Lübeck 1998-09--2001-06 Master's: Shandong University 1994-09--1998-06 Bachelor's: Shandong University
Work Experience	2009-09~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher, Group Leader 2008-10~2009-08 - Wadsworth Center, New York State Department of Health, USA - Research Scientist I 2006-01~2008-10 - Wadsworth Center, New York State Department of Health, USA - Postdoctoral Fellow 2001-07~2002-06 - Beijing Genomics Institute - Researcher
Awards	Outstanding Graduate Advisor Award (2019): Wuhan Education Base, Chinese Academy of Sciences Military Science and Technology Progress Award, First Prize (2018): Other

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2002-06--2005-11 PhD: University of Lübeck
1998-09--2001-06 Master's: Shandong University
1994-09--1998-06 Bachelor's: Shandong University

Work Experience

2009-09~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher, Group Leader
2008-10~2009-08 - Wadsworth Center, New York State Department of Health, USA - Research Scientist I
2006-01~2008-10 - Wadsworth Center, New York State Department of Health, USA - Postdoctoral Fellow
2001-07~2002-06 - Beijing Genomics Institute - Researcher

Awards

Outstanding Graduate Advisor Award (2019): Wuhan Education Base, Chinese Academy of Sciences
Military Science and Technology Progress Award, First Prize (2018): Other

Areas of Focus	Mechanisms of Flavivirus and Alphavirus Replication and Packaging Development of Novel Vaccines Antiviral Drug Research
Publications	An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, HongQing Zhang, YaNan Zhang, ZheRui Zhang, XiaoLing Chen, YanYan Hu, YuJia Shi, Jing Wang, Chenglin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2023 A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, Na Li, ChengLin Deng, Qi Li, XiaoLing Chen, Bo Zhang, HanQing Ye, 2023 Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters, YaNan Zhang, ZheRui Zhang, HongQing Zhang, Na Li, QiuYan Zhang, XiaoDan Li, ChengLin Deng, Fei Deng, Shuo Shen, Bing Zhu, Bo Zhang, 2022 ACE2-Targeting antibody suppresses SARS-CoV-2 Omicron and Delta variants, Jianxia Ou, Yanan Zhang, Yongmei Wang, Zherui Zhang, Hongping Wei, Junping Yu, Qi Wang, Guifeng Wang, Bo Zhang, Chunhe Wang, 2022 A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, Na Li, XiaoLing Chen, Qi Li, ZheRui Zhang, ChengLin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2022 Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, Zhang, QiuYan, Liu, SiQing, Li, XiaoDan, Li, JiaQi, Zhang, YaNan, Deng, ChengLin, Zhang, HongLei, Li, XuFang, Fang, ChunXiao, Yang, FengXia, Zhang, Bo, Xu, Yi, Ye, HanQing, 2022 Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection, Zhang, Shihai, Pei, Rongjuan, Li, Meixia, Su, Haixia, Sun, Hao, Ding, Yaqi, Su, Minbo, Huang, Chunfan, Chen, Xia, Du, Zhenyun, Jin, Can, Zang, Yi, Li, Jia, Xu, Yechun, Chen, Xinwen, Zhang, Bo, Ding, Kan, 2022 Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement, Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, JIawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui, 2022 Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses, Yang, Jieyu, Jing, Xuping, Yi, Wenfu, Li, XiaoDan, Yao, Chen, Zhang, Bo, Zheng, Zhenhua, Wang, Hanzhong, Gong, Peng, 2021 Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2, Zhang, YaNan, Zhang, ZheRui, Zhang, HongQing, Li, XiaoDan, Li, JiaQi, Zhang, QiuYan, Liu, Jing, Li, Qi, Deng, ChengLin, Shi, ZhengLi, Yuan, ZhiMing, Ye, HanQing, Zhang, Bo, 2021

Areas of Focus

Mechanisms of Flavivirus and Alphavirus Replication and Packaging
Development of Novel Vaccines
Antiviral Drug Research

Publications

An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, HongQing Zhang, YaNan Zhang, ZheRui Zhang, XiaoLing Chen, YanYan Hu, YuJia Shi, Jing Wang, Chenglin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2023
A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, Na Li, ChengLin Deng, Qi Li, XiaoLing Chen, Bo Zhang, HanQing Ye, 2023
Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters, YaNan Zhang, ZheRui Zhang, HongQing Zhang, Na Li, QiuYan Zhang, XiaoDan Li, ChengLin Deng, Fei Deng, Shuo Shen, Bing Zhu, Bo Zhang, 2022
ACE2-Targeting antibody suppresses SARS-CoV-2 Omicron and Delta variants, Jianxia Ou, Yanan Zhang, Yongmei Wang, Zherui Zhang, Hongping Wei, Junping Yu, Qi Wang, Guifeng Wang, Bo Zhang, Chunhe Wang, 2022
A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, Na Li, XiaoLing Chen, Qi Li, ZheRui Zhang, ChengLin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2022
Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, Zhang, QiuYan, Liu, SiQing, Li, XiaoDan, Li, JiaQi, Zhang, YaNan, Deng, ChengLin, Zhang, HongLei, Li, XuFang, Fang, ChunXiao, Yang, FengXia, Zhang, Bo, Xu, Yi, Ye, HanQing, 2022
Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection, Zhang, Shihai, Pei, Rongjuan, Li, Meixia, Su, Haixia, Sun, Hao, Ding, Yaqi, Su, Minbo, Huang, Chunfan, Chen, Xia, Du, Zhenyun, Jin, Can, Zang, Yi, Li, Jia, Xu, Yechun, Chen, Xinwen, Zhang, Bo, Ding, Kan, 2022
Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement, Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, JIawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui, 2022
Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses, Yang, Jieyu, Jing, Xuping, Yi, Wenfu, Li, XiaoDan, Yao, Chen, Zhang, Bo, Zheng, Zhenhua, Wang, Hanzhong, Gong, Peng, 2021
Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2, Zhang, YaNan, Zhang, ZheRui, Zhang, HongQing, Li, XiaoDan, Li, JiaQi, Zhang, QiuYan, Liu, Jing, Li, Qi, Deng, ChengLin, Shi, ZhengLi, Yuan, ZhiMing, Ye, HanQing, Zhang, Bo, 2021

Flavivirus Alphavirus Replication Packaging Vaccine Novel Antiviral Drug Mechanism Research

Lian Huan - Wuhan University

Jijun Chen - University of Chinese Academy of Sciences

Lei Sun - University of Chinese Academy of Sciences

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