Areas of Focus
- Mechanisms of Flavivirus and Alphavirus Replication and Packaging
- Development of Novel Vaccines
- Antiviral Drug Research
Work Experience
- 2009-09~Present - Wuhan Institute of Virology, Chinese Academy of Sciences - Researcher, Group Leader
- 2008-10~2009-08 - Wadsworth Center, New York State Department of Health, USA - Research Scientist I
- 2006-01~2008-10 - Wadsworth Center, New York State Department of Health, USA - Postdoctoral Fellow
- 2001-07~2002-06 - Beijing Genomics Institute - Researcher
Academic Background & Achievements
- 2002-06--2005-11 PhD: University of Lübeck
- 1998-09--2001-06 Master's: Shandong University
- 1994-09--1998-06 Bachelor's: Shandong University
Publications
- An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, HongQing Zhang, YaNan Zhang, ZheRui Zhang, XiaoLing Chen, YanYan Hu, YuJia Shi, Jing Wang, Chenglin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2023
- A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, Na Li, ChengLin Deng, Qi Li, XiaoLing Chen, Bo Zhang, HanQing Ye, 2023
- Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters, YaNan Zhang, ZheRui Zhang, HongQing Zhang, Na Li, QiuYan Zhang, XiaoDan Li, ChengLin Deng, Fei Deng, Shuo Shen, Bing Zhu, Bo Zhang, 2022
- ACE2-Targeting antibody suppresses SARS-CoV-2 Omicron and Delta variants, Jianxia Ou, Yanan Zhang, Yongmei Wang, Zherui Zhang, Hongping Wei, Junping Yu, Qi Wang, Guifeng Wang, Bo Zhang, Chunhe Wang, 2022
- A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, Na Li, XiaoLing Chen, Qi Li, ZheRui Zhang, ChengLin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2022
- Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, Zhang, QiuYan, Liu, SiQing, Li, XiaoDan, Li, JiaQi, Zhang, YaNan, Deng, ChengLin, Zhang, HongLei, Li, XuFang, Fang, ChunXiao, Yang, FengXia, Zhang, Bo, Xu, Yi, Ye, HanQing, 2022
- Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection, Zhang, Shihai, Pei, Rongjuan, Li, Meixia, Su, Haixia, Sun, Hao, Ding, Yaqi, Su, Minbo, Huang, Chunfan, Chen, Xia, Du, Zhenyun, Jin, Can, Zang, Yi, Li, Jia, Xu, Yechun, Chen, Xinwen, Zhang, Bo, Ding, Kan, 2022
- Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement, Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, JIawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui, 2022
- Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses, Yang, Jieyu, Jing, Xuping, Yi, Wenfu, Li, XiaoDan, Yao, Chen, Zhang, Bo, Zheng, Zhenhua, Wang, Hanzhong, Gong, Peng, 2021
- Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2, Zhang, YaNan, Zhang, ZheRui, Zhang, HongQing, Li, XiaoDan, Li, JiaQi, Zhang, QiuYan, Liu, Jing, Li, Qi, Deng, ChengLin, Shi, ZhengLi, Yuan, ZhiMing, Ye, HanQing, Zhang, Bo, 2021
Awards
- Outstanding Graduate Advisor Award (2019): Wuhan Education Base, Chinese Academy of Sciences
- Military Science and Technology Progress Award, First Prize (2018): Other
