Areas of Focus
- 黄病毒和甲病毒属病毒复制包装机制
- 新型疫苗的研发
- 抗病毒药物研究
Work Experience
- 2009-09~现在 - 中国科学院武汉病毒研究所 - 研究员、学科组长
- 2008-10~2009-08 - 美国纽约州州立卫生署Wadsworth Center - 研究科学家I
- 2006-01~2008-10 - 美国纽约州州立卫生署Wadsworth Center - 博士后
- 2001-07~2002-06 - 北京华大基因研究中心 - 研究人员
Academic Background & Achievements
- 2002-06--2005-11 博士: 德国吕贝克大学
- 1998-09--2001-06 硕士: 山东大学
- 1994-09--1998-06 学士: 山东大学
Publications
- An alphavirus replicon particle delivering prefusion-stabilized spike protein provides potent immunoprotection against SARS-CoV-2 Omicron variant, HongQing Zhang, YaNan Zhang, ZheRui Zhang, XiaoLing Chen, YanYan Hu, YuJia Shi, Jing Wang, Chenglin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2023
- A safe replication-defective Zika virus vaccine protects mice from viral infection and vertical transmission, Na Li, ChengLin Deng, Qi Li, XiaoLing Chen, Bo Zhang, HanQing Ye, 2023
- Different pathogenesis of SARS-CoV-2 Omicron variant in wild-type laboratory mice and hamsters, YaNan Zhang, ZheRui Zhang, HongQing Zhang, Na Li, QiuYan Zhang, XiaoDan Li, ChengLin Deng, Fei Deng, Shuo Shen, Bing Zhu, Bo Zhang, 2022
- ACE2-Targeting antibody suppresses SARS-CoV-2 Omicron and Delta variants, Jianxia Ou, Yanan Zhang, Yongmei Wang, Zherui Zhang, Hongping Wei, Junping Yu, Qi Wang, Guifeng Wang, Bo Zhang, Chunhe Wang, 2022
- A new screening system for entry inhibitors based on cell-to-cell transmitted syncytia formation mediated by self-propagating hybrid VEEV-SARS-CoV-2 replicon, Na Li, XiaoLing Chen, Qi Li, ZheRui Zhang, ChengLin Deng, Bo Zhang, XiaoDan Li, HanQing Ye, 2022
- Sequence duplication in 3 ' UTR modulates virus replication and virulence of Japanese encephalitis virus, Zhang, QiuYan, Liu, SiQing, Li, XiaoDan, Li, JiaQi, Zhang, YaNan, Deng, ChengLin, Zhang, HongLei, Li, XuFang, Fang, ChunXiao, Yang, FengXia, Zhang, Bo, Xu, Yi, Ye, HanQing, 2022
- Cocktail polysaccharides isolated from Ecklonia kurome against the SARS-CoV-2 infection, Zhang, Shihai, Pei, Rongjuan, Li, Meixia, Su, Haixia, Sun, Hao, Ding, Yaqi, Su, Minbo, Huang, Chunfan, Chen, Xia, Du, Zhenyun, Jin, Can, Zang, Yi, Li, Jia, Xu, Yechun, Chen, Xinwen, Zhang, Bo, Ding, Kan, 2022
- Self-Assembling Nanovaccine Confers Complete Protection Against Zika Virus Without Causing Antibody-Dependent Enhancement, Heng Rong, Mi Qi, Jingdi Pan, Yuhan Sun, JIawang Gao, Xiaowei Zhang, Wei Li, Bo Zhang, Xian-En Zhang, Zongqiang Cui, 2022
- Crystal structure of a tick-borne flavivirus RNA-dependent RNA polymerase suggests a host adaptation hotspot in RNA viruses, Yang, Jieyu, Jing, Xuping, Yi, Wenfu, Li, XiaoDan, Yao, Chen, Zhang, Bo, Zheng, Zhenhua, Wang, Hanzhong, Gong, Peng, 2021
- Increased morbidity of obese mice infected with mouse-adapted SARS-CoV-2, Zhang, YaNan, Zhang, ZheRui, Zhang, HongQing, Li, XiaoDan, Li, JiaQi, Zhang, QiuYan, Liu, Jing, Li, Qi, Deng, ChengLin, Shi, ZhengLi, Yuan, ZhiMing, Ye, HanQing, Zhang, Bo, 2021
Awards
- 优秀研究生指导教师奖 (2019): 中国科学院武汉教育基地
- 军队科技进步奖, 一等奖 (2018): 其他
