Professor | Jiangyu Zhao | Asia Growth Partners

Name	Jiangyu Zhao
Contact Information	zhaojy@ms.xjb.ac.cn
Language ability	Chinese, English
Province	Xinjiang

Name

Jiangyu Zhao

Contact Information

zhaojy@ms.xjb.ac.cn

Language ability

Chinese, English

Province

Xinjiang

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Medical School
Academic Background & Achievements	2008-09--2011-12 PhD: Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences 2004-09--2007-07 Master's: Nankai University 2000-09--2004-07 Bachelor's: Xinzhou Teachers University
Work Experience	2014-10~Present - Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences - Associate Researcher 2012-03~2014-09 - Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences - Assistant Researcher 2007-09~2008-07 - Xinjiang Science and Technology School - Teacher
Awards	First Prize, 13th Xinjiang Excellent Academic Papers in Natural Science (2014) Second Prize, 12th Xinjiang Excellent Academic Papers in Natural Science (2012)

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Medical School

Academic Background & Achievements

2008-09--2011-12 PhD: Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences
2004-09--2007-07 Master's: Nankai University
2000-09--2004-07 Bachelor's: Xinzhou Teachers University

Work Experience

2014-10~Present - Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences - Associate Researcher
2012-03~2014-09 - Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences - Assistant Researcher
2007-09~2008-07 - Xinjiang Science and Technology School - Teacher

Awards

First Prize, 13th Xinjiang Excellent Academic Papers in Natural Science (2014)
Second Prize, 12th Xinjiang Excellent Academic Papers in Natural Science (2012)

Areas of Focus	Structure-activity relationship of natural compounds Organic chemistry
Publications	Pharmacokinetic study and metabolite identification of CAM106 in rats by validated UHPLC-MS/MS, Ruqi Xi, Rahima Abdulla, Jiangyu Zhao, Haji Akber Aisa, Yongqiang Liu, 2023 Furo2,3-dpyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study, Song, Buer, Nie, Lifei, Bozorov, Khurshed, Niu, Chao, Kuryazov, Rustamkhon, Akber Aisa, Haji, Zhao, Jiangyu, 2023 2,5-二氨基噻吩-3，4-二羧酸二乙酯衍生物的合成及抗肿瘤活性研究, 张维舒, 聂礼飞, Khurshed Bozorov, 阿吉艾克拜尔·艾萨, 赵江瑜, 2023 1，2，3-三氮唑并4，5-d嘧啶酮三环类衍生物的合成及抗肿瘤活性研究, 刘奇, 聂礼飞, BOZOROV, Khurshed, 赵江瑜, 2021 Diterpenoid alkaloids from Aconitum barbatum var. puberulum Ledeb, Ablajan, Nurfida, Zhao, Bo, Zhao, JiangYu, Wang, BianLin, Sagdullaev, Sh Sh, Aisa, H A, 2021 Two new C-19-diterpenoid alkaloids from Aconitum smirnovii, Zhao, Bo, Ablajan, Nurfida, Zhao, JiangYu, Kodirova, D R, Sagdullaev, Sh Sh, Aisa, H A, 2020 Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L, Yuan, WenJuan, Gao, WenFen, Zhao, JiangYu, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang, 2020 Novel amides modified rupestonic acid derivatives as anti-influenza virus reagents, Li, Gen, Obul, Mamateli, Zhao, Jiangyu, Liu, Geyu, Lu, Wei, Aisa, Haji Akber, 2019 Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang, Xue, WenJuan, Zhao, Bo, Zhao, JiangYu, Sagdullaev, Sh Sh, Aisa, Haji Akber, 2019 1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview, Bozorov, Khurshed, Zhao, Jiangyu, Aisa, Haji A, 2019 Structural modification on rupestonic acid leads to highly potent inhibitors against influenza virus, Obul, Mamateli, Wang, Xincheng, Zhao, Jiangyu, Li, Gen, Aisa, Haji Akber, Huang, Guozheng, 2019 Synthesis, characterization, and antimicrobial activity of novel hydrazone-bearing tricyclic quinazolines, Nasrullaev, Azizbek, Bozorov, Khurshed, Bobakulov, Khayrulla, Zhao, Jiangyu, Nie, Li Fei, Turgunov, Kambarali K, Elmuradov, Burkhon, Aisa, Haji A, 2019 Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation their influence on melanin synthesis in murine B16 cells, 黄国正, 2018 Design, synthesis, and toward a side-ring optimization of tricyclic thieno2,3-dpyrimidin-4(3H)-ones and their effect on melanin synthesis in murine B16 cells, Nie, Li Fei, Bozorov, Khurshed, Huang, Guozheng, Zhao, Jiangyu, Niu, Chao, Aisa, Haji Akber, 2018 Diversity-oriented synthesis of amide derivatives of tricyclic thieno2,3-d pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells (vol 24, pg 43, 2018), Nie, Li Fei, Huang, Guozheng, Bozorov, Khurshed, Zhao, Jiangyu, Niu, Chao, Sagdullaev, Shamansur S, Aisa, Haji A, 2018 Total synthesis of rupestine G and its epimers, Yusuf, Abdullah, Zhao, Jiangyu, Wang, Bianlin, Aibibula, Paruke, Aisa, Haji Akber, Huang, Guozheng, 2018 DITERPENE ALKALOIDS FROM Aconitum smirnovii, Zhao, B, Zhao, J Y, Sagdullaev, Sh Sh, Aisa, H A, 2018 Diterpenoid Alkaloids from Delphinium aemulans, Ablajan, Nurfida, Zhao, Bo, Xue, Wenjuan, Ruzi, Zukela, Zhao, Jiangyu, Aisa, Haji Akber, 2018 Norditerpenoid alkaloids from Delphinium pseudoaemulans C. Y. Yang et B. Wang, Xue, WenJuan, Zhao, Bo, Ruzi, Zukela, Zhao, JiangYu, Aisa, Haji Akber, 2018 Structure-activity relationship studies of 1-(1 '-hydroxyalkyl)rupestonic acid methyl esters against influenza viruses, Li, Gen, Zhao, JiangYu, Niu, Chao, Nie, LiFei, Dong, ChangZhi, Aisa, Haji Akber, 2017 Structure–activity relationship studies of 1-(10-hydroxyalkyl) rupestonic acid methyl esters against influenza viruses, Zhao Jiangyu, 2017 Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and antiinfluenza virus agents. Part, Bozorov, Khurshed, Zhao, Jiang Yu, Nie, Li Fei, Ma, HaiRong, Bobakulov, Khayrulla, Hu, Rui, Rustamova, Nigora, Huang, Guozheng, Efferth, Thomas, Aisa, Haji A, 2017 2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry, Bozorov, Khurshed, Nie, Li Fei, Zhao, Jiangyu, Aisa, Haji A, 2017 Synthesis of Rupestonic Acid Derivatives with Antiviral Activity, Zhao, Jiangyu, Niu, Chao, Li, Gen, Aisa, Haji Akber, 2017 Recent advances in ipso-nitration reactions, Khurshed Bozorov, JiangYu Zhao, Haji A Aisa, 2016 Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo, Niu, Chao, Yin, Li, Nie, Li Fei, Dou, Jun, Zhao, Jiang Yu, Li, Gen, Aisa, Haji Aker, 2016 Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response, Ma, LinLin, Wang, HuiQiang, Wu, Ping, Hu, Jin, Yin, JinQiu, Wu, Shuo, Ge, Miao, Sun, WenFang, Zhao, JiangYu, Aisa, Haji Akber, Li, YuHuan, Jiang, JianDoug, 2016 Recent developments regarding the use of thieno2,3-dpyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties, Bozorov, Khurshed, Zhao, JiangYu, Elmuradov, Burkhon, Pataer, Apar, Aisa, Haji A, 2015 Identification of metabolites of rupestonic acid in rat urine by liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Gu, Dongyu, Yang, Yi, Chen, Qibin, Habasi, Madina, Zhao, Jiangyu, Aisa, Haji Akber, 2015 Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: Synthesis and in vitro biological evaluation. Part 1, Bozorov, Khurshed, Ma, HaiRong, Zhao, JiangYu, Zhao, HaiQing, Chen, Hua, Bobakulov, Khayrulla, Xin, XueLei, Elmuradov, Burkhon, Shakhidoyatov, Khusnutdin, Aisa, Haji A, 2014 1,2,3-Triazole-containing derivatives of rupestonic acid: Click-chemical synthesis and antiviral activities against influenza viruses, He, YaoWu, Dong, ChangZhi, Zhao, JiangYu, Ma, LinLin, Li, YuHuan, Aisa, Haji Akber, 2014 新型一枝蒿酮酸异噁唑衍生物的合成及其抗A，B型流感病毒活性研究

Areas of Focus

Structure-activity relationship of natural compounds
Organic chemistry

Publications

Pharmacokinetic study and metabolite identification of CAM106 in rats by validated UHPLC-MS/MS, Ruqi Xi, Rahima Abdulla, Jiangyu Zhao, Haji Akber Aisa, Yongqiang Liu, 2023
Furo2,3-dpyrimidines as Mackinazolinone/Isaindigotone Analogs: Synthesis, Modification, Antitumor Activity, and Molecular Docking Study, Song, Buer, Nie, Lifei, Bozorov, Khurshed, Niu, Chao, Kuryazov, Rustamkhon, Akber Aisa, Haji, Zhao, Jiangyu, 2023
2,5-二氨基噻吩-3，4-二羧酸二乙酯衍生物的合成及抗肿瘤活性研究, 张维舒, 聂礼飞, Khurshed Bozorov, 阿吉艾克拜尔·艾萨, 赵江瑜, 2023
1，2，3-三氮唑并4，5-d嘧啶酮三环类衍生物的合成及抗肿瘤活性研究, 刘奇, 聂礼飞, BOZOROV, Khurshed, 赵江瑜, 2021
Diterpenoid alkaloids from Aconitum barbatum var. puberulum Ledeb, Ablajan, Nurfida, Zhao, Bo, Zhao, JiangYu, Wang, BianLin, Sagdullaev, Sh Sh, Aisa, H A, 2021
Two new C-19-diterpenoid alkaloids from Aconitum smirnovii, Zhao, Bo, Ablajan, Nurfida, Zhao, JiangYu, Kodirova, D R, Sagdullaev, Sh Sh, Aisa, H A, 2020
Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L, Yuan, WenJuan, Gao, WenFen, Zhao, JiangYu, Zhang, Yu, Chen, DuoZhi, Li, ShunLin, Di, YingTong, Hao, XiaoJiang, 2020
Novel amides modified rupestonic acid derivatives as anti-influenza virus reagents, Li, Gen, Obul, Mamateli, Zhao, Jiangyu, Liu, Geyu, Lu, Wei, Aisa, Haji Akber, 2019
Three new diterpenoid alkaloids from Delphinium naviculare var. lasiocarpum W. T. Wang, Xue, WenJuan, Zhao, Bo, Zhao, JiangYu, Sagdullaev, Sh Sh, Aisa, Haji Akber, 2019
1,2,3-Triazole-containing hybrids as leads in medicinal chemistry: A recent overview, Bozorov, Khurshed, Zhao, Jiangyu, Aisa, Haji A, 2019
Structural modification on rupestonic acid leads to highly potent inhibitors against influenza virus, Obul, Mamateli, Wang, Xincheng, Zhao, Jiangyu, Li, Gen, Aisa, Haji Akber, Huang, Guozheng, 2019
Synthesis, characterization, and antimicrobial activity of novel hydrazone-bearing tricyclic quinazolines, Nasrullaev, Azizbek, Bozorov, Khurshed, Bobakulov, Khayrulla, Zhao, Jiangyu, Nie, Li Fei, Turgunov, Kambarali K, Elmuradov, Burkhon, Aisa, Haji A, 2019
Diversity-oriented synthesis of amide derivatives of tricyclic thieno[2,3-d]pyrimidin-4(3H)-ones and evaluation their influence on melanin synthesis in murine B16 cells, 黄国正, 2018
Design, synthesis, and toward a side-ring optimization of tricyclic thieno2,3-dpyrimidin-4(3H)-ones and their effect on melanin synthesis in murine B16 cells, Nie, Li Fei, Bozorov, Khurshed, Huang, Guozheng, Zhao, Jiangyu, Niu, Chao, Aisa, Haji Akber, 2018
Diversity-oriented synthesis of amide derivatives of tricyclic thieno2,3-d pyrimidin-4(3H)-ones and evaluation of their influence on melanin synthesis in murine B16 cells (vol 24, pg 43, 2018), Nie, Li Fei, Huang, Guozheng, Bozorov, Khurshed, Zhao, Jiangyu, Niu, Chao, Sagdullaev, Shamansur S, Aisa, Haji A, 2018
Total synthesis of rupestine G and its epimers, Yusuf, Abdullah, Zhao, Jiangyu, Wang, Bianlin, Aibibula, Paruke, Aisa, Haji Akber, Huang, Guozheng, 2018
DITERPENE ALKALOIDS FROM Aconitum smirnovii, Zhao, B, Zhao, J Y, Sagdullaev, Sh Sh, Aisa, H A, 2018
Diterpenoid Alkaloids from Delphinium aemulans, Ablajan, Nurfida, Zhao, Bo, Xue, Wenjuan, Ruzi, Zukela, Zhao, Jiangyu, Aisa, Haji Akber, 2018
Norditerpenoid alkaloids from Delphinium pseudoaemulans C. Y. Yang et B. Wang, Xue, WenJuan, Zhao, Bo, Ruzi, Zukela, Zhao, JiangYu, Aisa, Haji Akber, 2018
Structure-activity relationship studies of 1-(1 '-hydroxyalkyl)rupestonic acid methyl esters against influenza viruses, Li, Gen, Zhao, JiangYu, Niu, Chao, Nie, LiFei, Dong, ChangZhi, Aisa, Haji Akber, 2017
Structure–activity relationship studies of 1-(10-hydroxyalkyl) rupestonic acid methyl esters against influenza viruses, Zhao Jiangyu, 2017
Synthesis and in vitro biological evaluation of novel diaminothiophene scaffolds as antitumor and antiinfluenza virus agents. Part, Bozorov, Khurshed, Zhao, Jiang Yu, Nie, Li Fei, Ma, HaiRong, Bobakulov, Khayrulla, Hu, Rui, Rustamova, Nigora, Huang, Guozheng, Efferth, Thomas, Aisa, Haji A, 2017
2-Aminothiophene scaffolds: Diverse biological and pharmacological attributes in medicinal chemistry, Bozorov, Khurshed, Nie, Li Fei, Zhao, Jiangyu, Aisa, Haji A, 2017
Synthesis of Rupestonic Acid Derivatives with Antiviral Activity, Zhao, Jiangyu, Niu, Chao, Li, Gen, Aisa, Haji Akber, 2017
Recent advances in ipso-nitration reactions, Khurshed Bozorov, JiangYu Zhao, Haji A Aisa, 2016
Synthesis and bioactivity of novel isoxazole chalcone derivatives on tyrosinase and melanin synthesis in murine B16 cells for the treatment of vitiligo, Niu, Chao, Yin, Li, Nie, Li Fei, Dou, Jun, Zhao, Jiang Yu, Li, Gen, Aisa, Haji Aker, 2016
Rupestonic acid derivative YZH-106 suppresses influenza virus replication by activation of heme oxygenase-1-mediated interferon response, Ma, LinLin, Wang, HuiQiang, Wu, Ping, Hu, Jin, Yin, JinQiu, Wu, Shuo, Ge, Miao, Sun, WenFang, Zhao, JiangYu, Aisa, Haji Akber, Li, YuHuan, Jiang, JianDoug, 2016
Recent developments regarding the use of thieno2,3-dpyrimidin-4-one derivatives in medicinal chemistry, with a focus on their synthesis and anticancer properties, Bozorov, Khurshed, Zhao, JiangYu, Elmuradov, Burkhon, Pataer, Apar, Aisa, Haji A, 2015
Identification of metabolites of rupestonic acid in rat urine by liquid chromatography combined with electrospray ionization quadrupole time-of-flight tandem mass spectrometry, Gu, Dongyu, Yang, Yi, Chen, Qibin, Habasi, Madina, Zhao, Jiangyu, Aisa, Haji Akber, 2015
Discovery of diethyl 2,5-diaminothiophene-3,4-dicarboxylate derivatives as potent anticancer and antimicrobial agents and screening of anti-diabetic activity: Synthesis and in vitro biological evaluation. Part 1, Bozorov, Khurshed, Ma, HaiRong, Zhao, JiangYu, Zhao, HaiQing, Chen, Hua, Bobakulov, Khayrulla, Xin, XueLei, Elmuradov, Burkhon, Shakhidoyatov, Khusnutdin, Aisa, Haji A, 2014
1,2,3-Triazole-containing derivatives of rupestonic acid: Click-chemical synthesis and antiviral activities against influenza viruses, He, YaoWu, Dong, ChangZhi, Zhao, JiangYu, Ma, LinLin, Li, YuHuan, Aisa, Haji Akber, 2014
新型一枝蒿酮酸异噁唑衍生物的合成及其抗A，B型流感病毒活性研究

Natural Compounds Structure-Activity Relationship Organic Chemistry Antiviral Activity Synthesis Modification Pharmacokinetics Metabolite Identification Bioactivity Drug Development

Hongwei Liu - University of Chinese Academy of Sciences

Xiao Ding - University of Chinese Academy of Sciences

Jun Li - University of Chinese Academy of Sciences

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