2013-09 to 2018-10 Ph.D. in Pharmacology: Rutgers University, New Jersey, USA
2010-09 to 2012-12 Master's in Clinical Medicine: Shandong University School of Medicine
2004-09 to 2010-06 Bachelor's in Medicine: Shandong University School of Medicine
2019-04 to Present - Chinese Academy of Sciences Kunming Institute of Botany - Researcher
2018-10 to 2019-03 - Rutgers University New Jersey Cancer Institute - Postdoctoral Researcher
2011-12 to 2013-09 - University of Medicine and Dentistry of New Jersey - Visiting Scholar
National Outstanding Self-Financed International Student Scholarship (2017): National Level
NIH F99 Award (2017): Institutional Level
Aaron Shatkin Scholarship (2016): First Prize, Rutgers University
National Scholarship (2007): National Level
Shandong University Outstanding Student Scholarship (2007): First Prize, Institutional Level
Research
Mechanism of Gain-of-Function of Tumor-Related Mutant p53 Screening and Pharmacological Study of Small Molecule Compounds Targeting Mutant p53 Signaling Pathway
Eudesmane-guaiane sesquiterpenoid dimers from Aucklandia costus trigger paraptosis-like cell death via ROS accumulation and MAPK hyperactivation., Xiaolong Gao, Yuhan Zhao, et al., 2024
Isowalsuranolide targets TrxR1/2 and triggers lysosomal biogenesis and autophagy via the p53-TFEB/TFE3 axis., Xu Yang, Yuhan Zhao, et al., 2024
Iridoid glycosides from Morinda officinalis induce lysosomal biogenesis and promote autophagic flux to attenuate oxidative stress., Yinyuan Wang, Yuhan Zhao, et al., 2023
Acetylcholinesterase inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta., Jinliang Li, Yuhan Zhao, et al., 2023
Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress., Zhenpeng Niu, Yuhan Zhao, et al., 2023
Antifeedant Mechanism of Dodonaea viscosa Saponin A Isolated from the Seeds of Dodonaea viscosa., Hang Yu, Yuhan Zhao, et al., 2022
Nematicidal activity of tirotundin and parthenolide isolated from Tithonia diversifolia and Chrysanthemum parthenium., Mingxian Lan, Yuhan Zhao, et al., 2022
Identification of limonoids from Walsura yunnanensis and evaluation of their cytotoxicity against cancer cell lines., Yueqin Zhao, Yuhan Zhao, et al., 2022
Tumor suppressor p53 regulates intestinal type 2 immunity., ChunYuan Chang, Yuhan Zhao, et al., 2021
Tagitinin C induces ferroptosis through PERK-Nrf2-HO-1 signaling pathway in colorectal cancer cells., Ruiran Wei, Yuhan Zhao, et al., 2021
Tagitinin F诱导MDA-MB-231细胞凋亡作用机制研究., 娟 Wang, 赵逾涵, et al., 2021
LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome., Huaying Wang, Yuhan Zhao, et al., 2020
Inhibitory activities of flavonoids from Eupatorium adenophorum against acetylcholinesterase., Mengyue Li, Yuhan Zhao, et al., 2020
LIF is essential for ISC function and protects against radiation-induced gastrointestinal syndrome., Huaying Wang, Yuhan Zhao, et al., 2020
A polymorphism in the tumor suppressor p53 affects aging and longevity in mouse models., Yuhan Zhao, et al., 2018
Identification, validation, and targeting of the mutant p53-PARP-MCM chromatin axis in triple negative breast cancer., WeiGang Qiu, Yuhan Zhao, et al., 2017
MicroRNA Control of p53., Juan Liu, Yuhan Zhao, et al., 2017
Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression., Juan Liu, Yuhan Zhao, et al., 2017
Mutant p53 in Cancer: Accumulation, Gain-of-Function, and Therapy., Xuetian Yue, Yuhan Zhao, et al., 2017
Leukemia inhibitory factor promotes EMT through STAT3-dependent miR-21 induction., Xuetian Yue, Yuhan Zhao, et al., 2016
A novel mutant p53 binding partner BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis., Xuetian Yue, Yuhan Zhao, et al., 2016
Cullin3-KLHL25 ubiquitin ligase targets ACLY for degradation to inhibit lipid synthesis and tumor progression., Cen Zhang, Yuhan Zhao, et al., 2016
A novel mutant p53 binding partener BAG5 stabilizes mutant p53 and promotes mutant p53 GOFs in tumorigenesis., Yuhan Zhao, 2016
microRNA-1827 represses MDM2 to positively regulate tumor suppressor p53 and suppress tumorigenesis., Cen Zhang, Yuhan Zhao, et al., 2016
Pontin, a novel interactor of mutant p53 that promotes mutant p53 gain of function., Yuhan Zhao, et al., 2015
BAG2 promotes tumorigenesis through enhancing mutant p53 protein levels and function., Xuetian Yue, Yuhan Zhao, et al., 2015
HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells., Lihua Wu, Yuhan Zhao, et al., 2015
Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53., Yuhan Zhao, et al., 2015
Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma., Juan Liu, Yuhan Zhao, et al., 2014
LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway., Xiaoyan Li, Yuhan Zhao, et al., 2014
LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers., Haiyang Yu, Yuhan Zhao, et al., 2014
The regulation of MDM2 oncogene and its impact on human cancers., Yuhan Zhao, et al., 2014
Spliced MDM2 isoforms promote mutant p53 accumulation and gain-of-function in tumorigenesis., Tongsen Zheng, Yuhan Zhao, et al., 2013
Inhibition of metadherin sensitizes breast cancer cells to AZD6244., Xiaoli Kong, Yuhan Zhao, et al., 2012
53BP1 functions as a tumor suppressor in breast cancer via the inhibition of NF-kappa B through miR-146a., Xiaoyan Li, Yuhan Zhao, et al., 2012
Metadherin Mediates Lipopolysaccharide-Induced Migration and Invasion of Breast Cancer Cells., Yuhan Zhao, et al., 2011
