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Honglei Chen
Medical School
Wuhan University
Hubei
Language: Chinese, English
Tumor
Energy
Metabolism
Immune
Regulation
Microenvironment
Cancer
Lung
Mechanism
Autophagy
Areas of Focus
- Tumor energy metabolism and immune regulation
- Role of tumor microenvironment in cancer, especially lung cancer
Work Experience
- 2018.6-2019.9 Visiting Associate Professor, Translational Molecular Pathology, MD Anderson Cancer Center, USA
- 2017.12-present Deputy Chief Physician, Department of Pathology, Zhongnan Hospital of Wuhan University
- 2015.9-2015.12 Visiting Scholar, Department of Pathology, Fukushima Medical University, Japan
- 2014.9-2015.4 Advanced Studies, Department of Pathology, Obstetrics and Gynecology Hospital of Fudan University
- 2010.11-present Associate Professor, Department of Pathology, Basic Medical College of Wuhan University
- 2002.7-2010.10 Assistant, Lecturer, Department of Pathology, Basic Medical College of Wuhan University
Academic Background & Achievements
- 2012.5-2013.8 Postdoctoral Fellow, Department of Biochemistry, Rush University Medical Center, USA
- 2005.9-2010.6 PhD in Internal Medicine, Renmin Hospital of Wuhan University
- 1999.9-2002.7 Master in Pathology and Pathophysiology, Basic Medical College of Wuhan University
- 1994.9-1999.7 Bachelor in Clinical Medicine, Xian'ning Medical College
Publications
- Identification of a DNA-methylome-based signature for prognosis prediction in driver gene-negative lung adenocarcinoma, Shu M, Huang L, Chen Y, Wang C, Xie Z, Li S, Zhou J, Wei L, Fu T, Liu B, Chen H*, Tang K*, Ke Z*, 2024
- Targeting inhibition of prognosis-related lipid metabolism genes including CYP19A1 enhances immunotherapeutic response in colon cancer, Liu L, Mo M, Chen X, Chao D, Zhang Y, Chen X, Wang Y, Zhang N, He N, Yuan Y, Chen H*, Yang J*, 2023
- GOLM1 and FAM49B: potential biomarkers in HNSCC based on bioinformatics and immunohistochemical analysis, Xi Y, Zhang T, Sun W, Liang R, Ganesh S, Chen H*, 2022
- Different clinical significance of novel B7 family checkpoints, VISTA and HHLA2, in human lung adenocarcinoma, Long L, Zhang L, Yang Y, Zhou Y, Chen H*, 2022
- Recent Advancements in the mechanisms underlying resistance to PD-1/PD-L1 blockade immunotherapy, Yuan Y, Adam A, Zhao C, Chen H*, 2021
- High expression of PKM2 synergizes with PD-L1 in tumor cells and immune cells to predict worse survival in human lung adenocarcinoma, Long L, Chen M, Yuan Y, Ming AL, Guo W, Wu K*, Chen H*, 2020
- Clinicopathological and prognostic significance of caveolin-1 and ATG4C expression in the epithelial ovarian cancer, Zeng Y, Chen M, Ganesh S, Hu S*, Chen H*, 2020
- Targeting Immune Checkpoints in Lung Cancer: Current Landscape and Future Prospects, Long L, Zhao C, Ozarina M, Zhao X, Yang J, Chen H*, 2019
- High expression of synthesis of cytochrome c oxidase 2 and TP53-induced glycolysis and apoptosis regulator can predict poor prognosis in human lung adenocarcinoma, Liu J, Lu F, Gong Y, Zhao C, Pan Q, Ballantyne S, Zhao X, Tian S, Chen H*, 2018
- Role of glioma-associated GLI1 oncogene in carcinogenesis and cancer targeted therapy, Wu J, Di D, Zhao C, Liu Y, Chen H, Gong Y, Zhao X, Chen H*, 2018
Awards
- 2022 Hubei Province Teaching Achievement Third Prize (Fifth)
- 2021 Excellent Mentor Award in the 'Challenge Cup' College Students' Entrepreneurship Competition at Wuhan University
- 2019 Hubei Province Science and Technology Progress Second Prize (Second)
- 2015 Hubei Province Science and Technology Progress Third Prize (Third)
- 2005 Zhejiang Province Science and Technology Progress Third Prize (Fourth)
