Areas of Focus
- Paternal epigenetic inheritance
- RNA modifications and epigenetic regulation
Work Experience
- 2018-2021 - Second Affiliated Hospital of Army Medical University, PLA, China: Researcher
- 2021-present - Tongji University, School of Life Sciences and Technology: Professor under the 'Young 100 Talents Plan'
Academic Background & Achievements
- 2011 - Bachelor's Degree: Yanbian University
- 2014 - Master's Degree: Anhui University (Joint training with the Institute of Zoology, Chinese Academy of Sciences)
- 2018 - Doctorate Degree: University of Chinese Academy of Sciences, Institute of Zoology
- Received national scholarship for joint training at the University of Nevada, Reno School of Medicine
Publications
- Hypoxia induces alterations in tRNA modifications involved in translational control, Huanping Guo, Lin Xia, Wei Wang, Wei Xu, Xipeng Shen, Xiao Wu, Tong He, Xuelin Jiang, Yinying Xu, Pan Zhao, Dongmei Tan, Xi Zhang, Yunfang Zhang, 2023
- Human circulating small non-coding RNA signature as a non-invasive biomarker in clinical diagnosis of acute myeloid leukaemia, Lin Xia, Huanping Guo, Xiao Wu, Yinying Xu, Pan Zhao, Bingbing Yan, Yunjing Zeng, Yundi He, Dan Chen, Robert Peter Gale, Yunfang Zhang, Xi Zhang, 2023
- Alteration of RNA modification signature in human sperm correlates with sperm motility, Huanping Guo, Xipeng Shen, Hua Hu, Peng Zhou, Tong He, Lin Xia, Dongmei Tan, Xi Zhang, Yunfang Zhang, 2022
- Alterations of RNA Modification in Mouse Germ Cell-2 Spermatids Under Hypoxic Stress, Tong He, Huanping Guo, Lin Xia, Xipeng Shen, Yun Huang, Xiao Wu, Xuelin Jiang, Yinying Xu, Yi Tan, Yunfang Zhang, Dongmei Tan, 2022
- Paternal High-Fat Diet Altered Sperm 5‘tsRNA-Gly-GCC Is Associated with Enhanced Gluconeogenesis in the Offspring, Bin Wang, Lin Xia, Dan Zhu, Hongtao Zeng, Bin Wei, Likui Lu, Weisheng Li, Yajun Shi, Jingliu Liu, Yunfang Zhang, Mao Sun, 2022
- PANDORA-Seq expands the repertoire of regulatory small RNAs by overcoming RNA modifications, Junchao Shi, Yunfang Zhang, Dongmei Tan, Xudong Zhang, Menghong Yan, Ying Zhang, Marta Shahbazi, Kirsty Mackinlay, Reuben Franklin, Shichao Liu, Bemhard Kuhle, Emma R, James, Liwen Zhang, Yongcun Qu, Qiwei Zhai, Wenxin Zhao, Linlin Zhao, Changcheng Zhou, Weifeng Gu, Jernej Murn, Jingtao Guo, Douglas T. Carrell, Yingsheng Wang, Xuemei Chen, Bradley R. Cairms, Xianglei Yang, Paul Schimmel, Magdalena Zemicka-Goetz, Sihem Cheloufi, Ying Zhang, Tong Zhou, Qi Chen, 2021
- Hypoxia-induced alteration of RNA modifications in the mouse testis and sperm, Tong He, Huanping Guo, Xipeng Shen, Xiao Wu, Lin Xia, Xuelin Jiang, Yinying Xu, Dan Chen, Yunfang Zhang, Dongmei Tan, Yi Tan, 2021
- Sperm RNA code programmes the metabolic health of offspring, Yunfang Zhang, Junchao Shi, Minoo Rassoulzadegan, Francesca Tuorto, Qi Chen, 2019
- tsRNAs: The Swiss Army Knife for Translational Regulation, Jun Chao Shi, Yunfang Zhang, Tong Zhou, Qi Chen, 2019
- Dnmt2 mediates intergenerational transmission of paternally acquired metabolic disorders through sperm small non-coding RNAs, Yunfang Zhang, Xudong Zhang, Junchao Shi, Francesca Tuorto, Xin Li, Yusheng Liu, Reinhard Liebers, Tong Zhou, Wei Yan, Frank Lyko, Ying Zhang, Qi Zhou, Enkui Duan, Qi Chen, 2018
- tsRNAs: new players in mammalian retrotransposon control, Yunfang Zhang, Junchao Shi, Qi Chen, 2017
- Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder, Qi Chen, Menghong Yan, Zhonghong Cao, Xin Li, Yunfang Zhang, Junchao Shi, Gui-hai Feng, Hongying Peng, Xudong Zhang, Ying Zhang, Jingjing Qian, Enkui Duan, Qiwei Zhai, Qi Zhou, 2016
- Molecular carriers of acquired inheritance: absence of evidence is not evidence of absence, Junchao Shi, Yunfang Zhang, Qi Chen, 2016
- Identification and characterization of an ancient class of small RNAs enriched in serum associating with active infection, Yunfang Zhang, Ying Zhang, Junchao Shi, He Zhang, Zhonghong Cao, Xuan Gao, Wanhua Ren, Yunna Ning, Lina Ning, Yujing Cao, Yongchang Chen, Weizhi Ji, Zi-jiang Chen, Qi Chen, Enkui Duan, 2014
Awards
- 2016 - Included in 'China's Top Ten Scientific Progress' and 'Top Ten Progress in Life Sciences in China'
- 2019 - First Prize in Natural Science at the National Maternal and Child Health Science and Technology Award
