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Han Xiaodong
hanxd@nju.edu.cn
Chinese, English
Jiangsu
Nanjing University
Medical School
  • 1984 - Bachelor's Degree: Nanjing University, Department of Biology
  • 1987 - Master's Degree: Nanjing University, Department of Biology
  • 2004 - Ph.D.: Nanjing University, School of Life Sciences
  • 2001 - Senior Visiting Scholar: Harvard Medical School, Beth Israel Deaconess Medical Center
  • Published over 210 papers in domestic and international academic journals
  • Co-authored textbooks 'Histology and Embryology' and 'Reproductive Pathology'
  • Lectured 'Histology and Embryology', recognized as a provincial first-class undergraduate course
  • 2021: Nanjing University 'Zhao Shiliang Lecture Professor'
  • 2018: Nanjing University 'Excellent Undergraduate Practical Teaching Instructor'
  • 2017: 'Baosteel Excellent Teacher Award'
  • 2010: Nanjing University 'My Favorite Teacher'
Reproduction and Development
Environmental Pollution and Disease Occurrence
Stem Cells and Tissue Regeneration
  • Chronic exposure to MC-LR increases the risks of microcytic anemia: Evidence from human and mice, Pan Chun, Yan Minghao, Jin Haibo, Guo Hongqian, Han Xiaodong, 2021
  • MC-LR-induced interaction between M2 macrophage and biliary epithelial cell promotes biliary epithelial cell proliferation and migration through regulating STAT3, Minghao Yan, Shen Gu, Chun Pan, Yabing Chen, Han Xiaodong, 2021
  • Chronic MC-LR exposure promoted Aβ and p-tau accumulation via regulating Akt/GSK-3β signal pathway, Ma Yuhan, Wang Jing, Xu Dihui, Chen Yabing, Han Xiaodong, 2021
  • NLRP3 inflammasome activation in alveolar epithelial cells promotes myofibroblast differentiation of lung-resident mesenchymal stem cells during pulmonary fibrogenesis, Ji Jie, Hou Jiwei, Xia Yunhui, Xiang Zou, Han Xiaodong, 2021
  • Silencing of METTL3 effectively hinders invasion and metastasis of prostate cancer cells, Chen Yabing, Pan Chun, Wang Xiaotong, Xu Dihui, Ma Yuhan, Hu Jianhang, Chen Peilin, Xiang Zou, Rao Qiu, Han Xiaodong, 2021
  • Systematic toxicity evaluation of polystyrene nanoplastics on mice and molecular mechanism investigation about their internalization into Caco-2 cells, Xu Dihui, Ma Yuhan, Han Xiaodong, Chen Yabing, 2021
  • Co-delivery of siPTPN13 and siNOX4 via (myo)fibroblast -targeting polymeric micelles for idiopathic pulmonary fibrosis therapy, Hou Jiwei, Ji Qijian, Ji Jie, Ju Shenghong, Xu Chun, Yong Xueqing, Xu Xiaoxuan, Muddassir Mohd, Chen Xiang, Xie Jinbing, Han Xiaodong, 2021
  • Polystyrene microplastics induced male reproductive toxicity in mice, Jin Haibo, Ma Tan, Sha Xiaoxuan, Liu Zhengyu, Zhou Yuan, Meng Xiannan, Chen Yabing, Han Xiaodong, Die Jie, 2021
  • m6A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells, Chen Yabing, Wang Jing, Xu Dihui, Xiang Zou, Ding Jie, Yang Xiaoyu, Li Dongmei, Han Xiaodong, 2021
  • Microcystin-leucine-arginine induces apical ectoplasmic specialization disassembly, Xu Dihui, Wang Jing, Ma Yuhan, Ding Jie, Han Xiaodong, Chen Yabing, 2021
  • Chronic exposure to microcystin-LR increases the risk of prostate cancer and induces malignant transformation of human prostate epithelial cells, Pan Chun, Zhang Ling, Meng Xiannan, Qin Haixiang, Xiang Zou, Gong Wenyue, Luo Wenxin, Li Dongmei, Han Xiaodong, 2021
  • The mechanisms in the altered ontogenetic development and lung-related pathology in microcystin-leucine arginine (MC-LR)- paternal-exposed offspring mice, Meng Xiannan, Zhang Ling, Hou Jiwei, Ma Tan, Pan Chun, Zhou Yuan, Han Ruitong, Ding Yuanzhen, Peng Haoran, Zou Xiang, Li Dongmei, Han Xiaodong, 2020
  • Microcystin-leucine-arginine induced neurotoxicity by initiating mitochondrial fission in hippocampal neurons, Zhang Changliang, Wang Jing, Zhu Jinling, Chen Yabing, Han Xiaodong, 2020
  • Blood-brain barrier disruption and inflammation reaction in mice after chronic exposure to Microcystin-LR, Wang Jing, Zhang Changliang, Zhu Jinling, Ding Jie, Chen Yabing, Han Xiaodong, 2019
  • Learning and memory deficits and alzheimer's disease-like changes in mice after chronic exposure to microcystin-LR, Wang Jing, Chen Yabing, Zhang Changliang, Xiang Zou, Ding Jie, Han Xiaodong, 2019
  • A transcriptomic regulatory network among miRNAs, piRNAs, circRNAs, lncRNAs and mRNAs regulates microcystin-leucine arginine (MC-LR)-induced male reproductive toxicity, Meng Xiannan, Peng Haoran, Ding Yuanzhen, Zhang Ling, Yang Jingping, Han Xiaodong, 2019
  • M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis, Hou Jiwei, Shi Jingyan, Chen Ling, Lv Zhongyang, Chen Xiang, Cao Honghui, Xiang Zou, Han Xiaodong, 2018
  • Chronic exposure to microcystin-leucine-arginine promoted proliferation of prostate epithelial cells resulting in benign prostatic hyperplasia, Pan Chun, Chen Yabing, Xu Tianchi, Wang Jing, Li Dongmei, Han Xiaodong, 2018
  • Microcystin-LR reduces the synthesis of gonadotropin-releasing hormone by activating multiple signaling pathways resulting in decrease of testosterone in mice, Ding Jie, Wang Jing, Jin Haibo, Xia Tianjiao, Chen Yi, Wu Jiang, Han Xiaodong, 2018
  • The hedgehog and Wnt/β-catenin system machinery mediate myofibroblast differentiation of LR-MSCs in pulmonary fibrogenesis, Chen Xiang, Shi Chaowen, Cao Honghui, Chen Ling, Hou Jiwei, Xiang Zou, Hu Kebin, Han Xiaodong, 2018
  • Microcystin-leucine arginine causes blood-testis barrier disruption and degradation of occludin mediated by matrix metalloproteinase-8, Chen Yabing, Wang Jing, Han Xiaodong, 2018
  • Intracellular SERS probes based on -conjugated AuNSs for distinguishing between the differentiation of lung resident mesenchymal stem cells, Chaowen Shi, Xiang Chen, Zhaorui Sun, Zou xiang, Weiping Qian, Han Xiaodong, 2015
  • Regulation of Microcystin-LR-Induced Toxicity in Mouse Spermatogonia by miR-96, Yuan Zhou, Zou Xiang, Dongmei Li, Han Xiaodong, 2014
Reproduction Development Environmental Pollution Disease Stem Cells Tissue Regeneration Microcystin Pulmonary Fibrosis Testosterone Signal Pathways

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