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Zhiwei Wu
Medical School
Nanjing University
Jiangsu
Language: English, Chinese
Contact
Virus Immunity Vaccine Antiviral Extracellular Vesicles Pathology Rna Virus Host Interaction Nanobody Immunodiagnostic
Areas of Focus
  • Virus Infection and Immunity
  • Vaccine and Antiviral Drug Development
  • Extracellular Vesicles and Virus Pathology
  • RNA Virus and Host Cell Interaction
  • Nanobody Development for Virus Inhibition
  • Rapid Immunodiagnostic Reagents
Work Experience
  • 1990-1997 - Postdoctoral Training: New York University
  • 1997-2006 - Assistant Professor and Senior Researcher: Rockefeller University and University of Pennsylvania
  • 2006-Present - Professor and Director: Public Health Medicine Center, Nanjing University
Academic Background & Achievements
  • 1982 - Bachelor's Degree: Nanjing University
  • 1991 - Ph.D.: University of Edinburgh
  • 2006 - Established Public Health Medicine Center at Nanjing University
Publications
  • Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection, Yuxuan Fu, Li Zhang, Fang Zhang, Ting Tang, Chunhong Feng, Yu Jin, Zhiwei Wu, 2017
  • Deficient humoral response and disrupted B cell immunity are associated with fatal SFTSV infection, Peixin Song, Nan Zheng, Yong Liu, Chen Tian, Xilin Wu, Xiaohua Ma, Deyan Chen, Xue Zou, Guiyang Wang, Huanru Wang, Yongyang Zhang, Sufang Lu, Chao Wu, Zhiwei Wu, 2018
  • Development of a potent neutralizing nanobody as therapeutics against SFTSV infection, Xilin Wu, Yanlei Li, Xiaohua Ma, Linjing Zhu, Bilian Huang, Nan Zheng, Shijie Xu, Waqas Nawaz, Zhiwei Wu, 2020
  • Extracellular vesicles containing host restriction factor IFITM3 inhibited Zika virus infection of fetuses in pregnant mice through trans-placenta delivery, Xue Zou, Meng Yuan, Yutong Zhang, Nan Zheng, Zhiwei Wu, 2021
  • NanoTech and Immunoengineering: How nanotech can boost CAR-T therapy, Waqas Nawaz, Shijie Xu, Yanlei Li, Bilian Huang, Xilin Wu, Zhiwei Wu, 2020
  • The power of imaging to understand EV biology in vivo, Frederik J. Verweij, Leonora Balaj, Chantal Boulanger, David RF Carter, Ewaldus B Compeer, Gisela D’Angelo G, Samir El Andaloussi, Jacky G. Goetz, Julia Groß, Vincent Hyenne, Eva-Maria Krämer-Albers A, Charles Lai, Xavier Loyer, Alex Marki, Stefan Momma, Esther Nolte ‘t Hoen, Michiel D Pegtel, Hector Peinado, Graça Raposo, Kirsi Rilla, Hidetoshi Tahara, Clotilde Théry, Martin Van Royen, Roosmarijn Vandenbroecke, Ann Wehman, Kenneth Witwer, Zhiwei Wu, Richard Wubbolts, Guillaume van Niel, 2021
  • AAV-mediated in vivo CAR gene therapy for targeting human T-cell leukemia, Waqas Nawaz, Bilian Huang, Shijie Xu, Yanlei Li, Linjing Zhu, Hu Yiqiao, Zhiwei Wu, Xilin Wu, 2021
  • Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome, Shijie Xu, Na Jiang, Waqas Nawaz, Bingxin Liu, Fang Zhang, Ye Liu, Xilin Wu, Zhiwei Wu, 2021
  • Nonstructural protein NSs hampers cellular antiviral response through LSm14A during Severe Fever with Thrombocytopenia Syndrome Virus Infection, Li Zhang, Yuxuan Fu, Rui Zhang, Yajie Guan, Na Jiang, Nan Zheng, Zhiwei Wu, 2021
  • Potent bispecific nanobody provides in vivo protection against SARS-CoV-2 via intranasal administration, Xilin Wu, Lin Cheng, Ming Fu, Bilian Huang, Yalan Liu, Linjing Zhu, Shijie Xu, Haixia Shi, Doudou Zhang, Huanyun Yuan, Waqas Nawaz, Ping Yang, Qinxue Hu, Zhiwei Wu, 2021
Awards
  • Jiangsu Province Science and Technology Progress Award (Year Not Mentioned): Basic and Clinical Research on Severe Hand, Foot, and Mouth Disease Caused by EV71 Infection
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