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Minsheng Zhu
Medical School
Nanjing University
Jiangsu
Language: Chinese, English
Intestinal Microbiota
Smooth Muscle
Physiology
Gastrointestinal Motility
Asthma
Hypertension
Obesity
Disease Mechanisms
Translational Research
Mouse Genetics
Areas of Focus
- Intestinal Microbiota and Smooth Muscle Physiology
Work Experience
- 1999-2001 - University of Texas Southwestern Medical Center - Postdoctoral Researcher
- 2004-present - Nanjing University - Professor
Academic Background & Achievements
- 1995 PhD: Shanghai Institute of Biochemistry, Chinese Academy of Sciences
- Achievement: Published research in top journals like Gastroenterology, J Clin Invest, PNAS, etc.
- Achievement: 2016 National Science and Technology Progress Award (Second Place)
Publications
- Tas2R activation relaxes airway smooth muscle by release of Gαt targeting on AChR signaling, Zhou YW, Sun J, Wang Y, Chen CP, Tao T, Ma M, Chen X, Zhang XN, Yang LY, Zhang ZL, Li YQ, Jiang ZH, Qiu TT, Wang H, Pan Y, Zhang J, Chen HQ, Wang P, Zhu MS, 2022
- A Shigella sp. variant is causally linked to intractable functional constipation, Chen X, Qiu TT, Wang Y, Xu LY, Sun J, Jiang ZH, Zhao W, Tao T, Zhou YW, Wei L, Li Y, Zheng Y, Zhou GH, Chen H, Zhang J, Feng XB, Wang F, Li N, Zhang XN, Jiang J, Zhu MS, 2022
- The thymus regulates skeletal muscle regeneration by directly promoting satellite cell expansion, Zheng YY, Wang Y, Chen X, Wei LS, Wang H, Tao T, Zhou YW, Jiang ZH, Qiu TT, Sun ZY, Sun J, Wang P, Zhao W, Li YQ, Chen HQ, Zhu MS, Zhang XN, 2022
- LIMK2 is required for membrane cytoskeleton reorganization of contracting airway smooth muscle, Li Y, Zhou Y, Wang P, Tao T, Wei L, Wang Y, Wang W, Zheng Y, Jiang Z, Qiu T, Zhao W, Sun J, Chen X, Zhang XN, Zhu MS, 2021
- GGPP depletion initiates metaflammation through disequilibrating CYB5R3-dependent eicosanoid metabolism, Li-sha Wei, Yan-Yan Zheng, Jie Sun, Pei Wang, Tao Tao, Yeqiong Li, Xin Chen, Yongjuan Sang, Danyang Chong, Wei Zhao, Yuwei Zhou, Ye Wang, Zhihui Jiang, Tiantian Qiu, Chao-Jun Li, Min-Sheng Zhu, Xuena Zhang, 2020
- Intragenic MIR199A1 in the DNM2 gene contributes to the pathology of X-linked centronuclear myopathy, Chen X, Yun-Qian Gao, Yan-Yan Zheng, Wei Wang, Pei Wang, Juan Liang, Wei Zhao, Tao Tao, Jie Sun, Li-Sha Wei, Ye-Qiong Li, Yu-Wei Zhou, Zhen-Ji Gan, Xue-Na Zhang, Hua-Qun Chen, Min-Sheng Zhu, 2020
- CPI-17-mediated contraction of vascular smooth muscle is essential for the development of hypertension in obese mice, Sun J, Tao T, Zhao W, Wei LS, She F, Wang P, Li Y, Zheng Y, Chen X, Wang W, Qiao YN, Zhang XN, Zhu MS, 2019
- Golgi-resident TRIO regulates membrane trafficking during neurite outgrowth, Tao T, Sun J, Peng YJ, Li Y, Wang P, Chen X, Zhao W, Zheng YY, Wei LS, Wang W, Zhou YW, Liu J, Shi YS, Zhu MS, 2019
- Inflammatory Mediators Mediate Airway Smooth Muscle Contraction through a GPCR-TMEM16A-VDCC Axis and Contribute to Bronchial Hyperresponsiveness in Asthma, Pei Wang, Wei Zhao, Jie Sun, Tao Tao, Xin Chen, Yan-Yan Zheng, Cheng-Hai Zhang, Zhong Chen, Yun-Qian Gao, Fan She, Ye-Qiong Li, Li-Sha Wei, Ping Lu, Cai-Ping Chen, Ji Zhou, Da-Quan Wang, Liang Chen, Xiao-Hao Shi, Linhong Deng, Ronghua ZhuGe, Hua-Qun Chen, Min-Sheng Zhu, 2018
- An alternative novel tool for DNA editing without target sequence limitation: the structure-guided nuclease, Xu S, Cao S, Zou B, Yue Y, Gu C, Chen X, Wang P, Dong X, Xiang Z, Li K, Zhu MS, Zhao QS, Zhou GH, 2016
- The molecular basis underlying the genesis of basal tone in internal anal sphincter, Zhang CH, Wang P, Chen CP, Zhao W, Chen X, Chen C, He WQ, Qiao YN, Tao T, Sun J, Peng YJ, Craige SM, Lifshitz LM, Jr KJF, Fogarty KE, ZhuGe R, Zhu MS, 2016
- Regulation of DLK1 by the maternally expressed miR-379-544 cluster may underlie Callipyge polar overdominance inheritance, Gao YQ, Chen X, Wang P, Lu L, Zhao W, Chen C, Chen CP, Tao T, Sun J, Zheng YY, Du Jie, Li CJ, Gan ZJ, Gao X, Chen HQ, Zhu MS, 2015
- Roles in vivo for Myosin Phosphatase Targeting Subunit-1 T694 and T852 Phosphorylation sites in Bladder Smooth Muscle, Chen, C.P., Chen, X., Qiao, Y.N., Wang, P., He, W. Q., Zhang, C.H., Zhao, W., Gao, Y.Q., Chen, C., Tao, T., Sun, J., Wang, Y., Gao, N., Kamm, K.E., Stull, J.T., and Zhu, M.S, 2015
Awards
- 2016 National Science and Technology Progress Award (Second Place): Development and application of genetically engineered mouse models for related diseases
